Results 101 to 110 of about 2,596,942 (309)

Density-based crystal plasticity : from the discrete to the continuum

open access: yes, 2016
Because of the enormous range of time and space scales involved in dislocation dynamics, plastic modeling at macroscale requires a continuous formulation.
Appolaire, B.   +3 more
core   +2 more sources

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

Reduced integral scheme of damaged divided back stress elasto plastic model based on full implicit algorithm

open access: yesNihon Kikai Gakkai ronbunshu, 2015
The purpose of this study is formulating the reduced integration method of damage elasto plastic constitutive model with divided back stress based on full implicit framework.
Shogo SANNOMARU   +2 more
doaj   +1 more source

Back stress in dislocation creep. Part 1: Basic concepts and measuring techniques [PDF]

open access: yes
A theory is proposed whereby the plastic deformation of metal materials is determined by the difference between the applied stress and the back stress which characterizes the resistance of the material to plastic deformation.
Cadek, J.
core   +1 more source

Evaluation of a self-equilibrium cutting strategy for the contour method of residual stress measurement [PDF]

open access: yes, 2018
An assessment of cutting-induced plasticity (CIP) is performed, by finite element (FE) prediction of the plastic strain accumulation along the cut tip when the EDM wire sections the NeT TG4 weld benchmark specimen along two cutting directions.
Hamelin, C. J.   +3 more
core   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

open access: yesMolecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad   +12 more
wiley   +1 more source

Strain range dependent cyclic hardening of 08Ch18N10T stainless steel-experiments and simulations [PDF]

open access: yes, 2019
This paper describes and presents an experimental program of low-cycle fatigue tests of austenitic stainless steel 08Ch18N10T at room temperature. The low-cycle tests include uniaxial and torsional tests for various specimen geometries and for a vast ...
Fumfera, Jaromír   +4 more
core   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

Stress: Putting the Brain Back Into Medicine [PDF]

open access: yes, 2006
Throughout the life course stress plays a major role in health and disease. Although it has long been known that the brain orchestrates the many ways that the body responds to these experiences, a gap exists between health care providers who focus from ...
Judith Estrine, Lisa DeLisle
core  

Stress-Energy Tensor of the Quantized Massive Fields in Friedman-Robertson-Walker Spacetimes

open access: yes, 2013
The approximate stress-energy tensor of the quantized massive scalar, spinor and vector fields in the spatially flat Friedman-Robertson-Walker universe is constructed.
Matyjasek, Jerzy, Sadurski, Paweł
core   +1 more source

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