Results 131 to 140 of about 1,274,653 (285)

Evolutionary fine-tuning of background-matching camouflage among geographical populations in the sandy beach tiger beetle. [PDF]

Proc Biol Sci, 2020
Yamamoto N, Sota T.
europepmc   +1 more source

Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10

FEBS Open Bio, EarlyView.
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee, Ga Seul Lee, JinHan Kim, Kwang‐Hyun Park, Seong‐Ryung Go, Jeong Hee Moon, Eui‐Jeon Woo   +6 more
wiley   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Maintenance Service Supplier Selection for Complex Equipment in Military–Civilian Collaborative Background Considering Two-Stage Matching Perspective

Discrete Dynamics in Nature and Society
The maintenance of sophisticated equipment is of paramount importance, particularly in the military–civilian integration context. Traditional maintenance practices often rely on historical data and accumulated experience.
Qingwen Lu, Xin Huang, Xiaoyan Qi, Fenfang Cao   +3 more
doaj   +1 more source

BSVOS: Background Interference Suppression Strategy for Satellite Video Multiobject Segmentation

IEEE Journal of Selected Topics in Applied Earth Observations and Remote Sensing
Video satellites provide dynamic real-time monitoring of hotspot areas and objects by continuously imaging objects within a specified sequence, providing dynamic information over large areas.
Longxuan Kou, Shengyang Li, Jian Yang, Yixuan Lv   +3 more
doaj   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

Evaluation of color matching of single-shade resin composites with different background shades: an in vitro study

Scientific Reports
Contemporary single-shade resin composites claim to match all 16 VITA Classical shades using a single universal shade, simplifying clinical procedures and reducing technique sensitivity.
Fikret Yılmaz, Melek Taş Çinkılıç, Mücahit Enes Çinkılıç   +2 more
doaj   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Color matching and translucency of single-shade resin composites: effects of restoration thickness, background shade, and aging

BMC Oral Health
Background Achieving a seamless color match in resin composite restorations remains a significant clinical challenge due to variations in tooth structure and background shades.
Hamideh Sadat Mohammadipour, Soroush Sarafraz Yazdi, Mohammad Javad Moghaddas Mashhad, Saber Babazadeh, Arsalan Shahri   +4 more
doaj   +1 more source