Results 141 to 150 of about 362,507 (292)

Maintenance Service Supplier Selection for Complex Equipment in Military–Civilian Collaborative Background Considering Two-Stage Matching Perspective

open access: yesDiscrete Dynamics in Nature and Society
The maintenance of sophisticated equipment is of paramount importance, particularly in the military–civilian integration context. Traditional maintenance practices often rely on historical data and accumulated experience.
Qingwen Lu   +3 more
doaj   +1 more source

BSVOS: Background Interference Suppression Strategy for Satellite Video Multiobject Segmentation

open access: yesIEEE Journal of Selected Topics in Applied Earth Observations and Remote Sensing
Video satellites provide dynamic real-time monitoring of hotspot areas and objects by continuously imaging objects within a specified sequence, providing dynamic information over large areas.
Longxuan Kou   +3 more
doaj   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

Evaluation of color matching of single-shade resin composites with different background shades: an in vitro study

open access: yesScientific Reports
Contemporary single-shade resin composites claim to match all 16 VITA Classical shades using a single universal shade, simplifying clinical procedures and reducing technique sensitivity.
Fikret Yılmaz   +2 more
doaj   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

Color matching and translucency of single-shade resin composites: effects of restoration thickness, background shade, and aging

open access: yesBMC Oral Health
Background Achieving a seamless color match in resin composite restorations remains a significant clinical challenge due to variations in tooth structure and background shades.
Hamideh Sadat Mohammadipour   +4 more
doaj   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

open access: yesAging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang   +3 more
wiley   +1 more source

Building an effective and efficient background knowledge resource to enhance ontology matching

open access: yes, 2018
International audienceOntology matching is critical for data integration and interoperability. Original ontology matching approaches relied solely on the content of the ontologies to align.
Annane, Amina   +7 more
core   +1 more source

Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer

open access: yesAging and Cancer, EarlyView.
Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss   +12 more
wiley   +1 more source

Artificial Intelligence and Mental Well‐Being in Adult Education: Implications for Practice and Professional Responsibility

open access: yesNew Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Mental well‐being is central to adult learner success, yet many adult education institutions lack capacity to provide timely and accessible support. This article examines how artificial intelligence (AI) can strengthen mental health–adjacent supports in adult and continuing higher education, with attention to professional practice and ...
Adam L. McClain, Thomas Wade
wiley   +1 more source

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