Results 51 to 60 of about 220,925 (331)

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

FEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman, Anna E. Lester, Brian D. Zoltowski   +2 more
wiley   +1 more source

Perceived Direction of Self-Motion from Orthogonally Directed Visual and Vestibular Stimulation in Passive and Active Observation

i-Perception, 2011
Perceiving the direction of self-motion is typically a multisensory process. The most effective cue to detect the observer's heading direction is the visual optic-flow pattern.
Kenzo Sakurai, Toshio Kubodera, Philip M Grove, Shuichi Sakamoto, Yôiti Suzuki   +4 more
doaj   +1 more source

Toeplitz kernels and the backward shift [PDF]

Journal of Mathematical Analysis and Applications, 2020
In this paper we study the kernels of Toeplitz operators on both the scalar and the vector-valued Hardy space for $ 1 < p < \infty $. We show existence of a minimal kernel of any element of the vector-valued Hardy space and we determine a symbol for the corresponding Toeplitz operator.
openaire   +3 more sources

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Backward scattering of low-energy antiprotons by highly charged and neutral uranium: Coulomb glory

, 2007
Collisions of antiprotons with He-, Ne-, Ni-like, bare, and neutral uranium are studied theoretically for scattering angles close to 180$^{\circ}$ and antiproton energies with the interval 100 eV -- 10 keV.
A. V. Maiorova, D. A. Telnov, F. Calogero, G. F. Drukarev, G. Plunien, H. F. Beyer, I. I. Tupitsyn, L. D. Landau, T. Stöhlker, V. M. Shabaev, V. V. Babikov, V. V. Babikov, Yu. N. Demkov, Yu. N. Demkov   +13 more
core   +1 more source

On pole-swapping algorithms for the eigenvalue problem

, 2020
Pole-swapping algorithms, which are generalizations of the QZ algorithm for the generalized eigenvalue problem, are studied. A new modular (and therefore more flexible) convergence theory that applies to all pole-swapping algorithms is developed.
Camps, Daan, Mach, Thomas, Vandebril, Raf, Watkins, David S.   +3 more
core   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

On Using Lagrangian Drift Simulations to Aid Interpretation of in situ Monitoring Data

Frontiers in Marine Science, 2021
One key challenge of marine monitoring programs is to reasonably combine information from different in situ observations spread in space and time. In that context, we suggest the use of Lagrangian transport simulations extending both forward and backward
Ulrich Callies, Markus Kreus, Wilhelm Petersen, Yoana G. Voynova   +3 more
doaj   +1 more source

Backward shifts on function algebras

Journal of Mathematical Analysis and Applications, 2011
In [Canad. Math. Bull. 31, 85--94 (1988; Zbl 0658.47032)], \textit{J. R. Holub} introduced the concept of backward shifts on Banach spaces. In [J. Math. Anal. Appl. 202, 485--491 (1996; Zbl 0878.47014)], \textit{M. Rajagopalan} and \textit{K. Sundaresan} proved that \(C(X)\), the Banach space of all continuous function on a compact Hausdorff space \(X\)
Takagi, Hiroyuki, Koshimizu, Hironao, Ariizumi, Hiroaki   +2 more
openaire   +2 more sources

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source