Results 61 to 70 of about 8,740 (203)

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Plantas de cana-de-açúcar cultivadas in vitro com antibióticos Sugar cane plants cultivated in vitro with antibiotics

Ciência e Agrotecnologia, 2005
A contaminação por microrganismos é conhecida como um dos mais sérios problemas da cultura de tecidos de plantas, especialmente, em espécies tropicais. Com o objetivo de eliminar bactérias endofíticas, propágulos das cultivares de cana-de-açúcar Co 997 ...
Virgínia Maria Tenório Sabino Donato, Arnóbio Gonçalves de Andrade, Galba Maria de Campos Takaki, Rosa de Lima Ramos Mariano, Gabriel Alves Maciel   +4 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Gamma radiation treatment applied to microbial decontamination of products derived from eggs collected from the retail market in São Paulo

Arquivo Brasileiro de Medicina Veterinária e Zootecnia
The quality of products derived from eggs depends on the quality of the raw material source and the industrial production. The contamination by fungi and bacteria can occur after exposure of the product in the retail market.
S. Aquino, C.C. Lui, B. Corrêa
doaj   +1 more source

Caracterí­­sticas microbiológicas da carne de caranguejo-uçá (Ucides cordatus) comercializada na cidade de São Luí­­s - MA

Boletim do Instituto de Pesca, 2017
Com o objetivo de caracterizar microbiologicamente a carne de caranguejo-uçá (Ucides Cordatus) comercializada na cidade de São Luí­­s í  MA, foram analisadas 110 amostras da carne, 30 em 3 mercados (10/mercado) e 80 em 8 feiras livres (10/feira), na ...
Míryan Fabianny Nunes PINHEIRO, Lúcia Maria Coelho ALVES, Fernando Douglas Santos SILVA, Maria Cecília de Sousa CUNHA, Emanuelly de Oliveira MENDES, Francisca Neide COSTA   +5 more
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Metais pesados, densidade e atividade microbiana em solo contaminado por rejeitos de indústria de zinco

Revista Brasileira de Ciência do Solo, 1998
As atividades relacionadas com mineração e indústria metalúrgica são responsáveis pela poluição de extensas áreas de solo em todo o mundo, sendo seus efeitos ainda pouco conhecidos nas condições brasileiras.
H. E. Dias-Júnior, F. M. S. Moreira, J. O. Siqueira, R. Silva   +3 more
doaj   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

Establishment of a coculture system for Porphyromonas gingivalis and head and neck squamous cell carcinoma using spheroid culture and LATS inhibition

FEBS Open Bio, EarlyView.
We established a spheroid coculture system enabling viable Porphyromonas gingivalis–HNSCC interactions under normoxic conditions. Inhibition of LATS1/2 maintains tumor cells in an undifferentiated state, which may promote spheroid growth and create a more permissive environment for bacterial persistence.
Yurika Nakajima, Shogo Okazaki, Muneaki Tamura, Shuichi Sato, Kenichi Imai   +4 more
wiley   +1 more source

Dinâmica fermentativa e microbiológica de silagens dos capins tanzânia e marandu acrescidas de polpa cítrica peletizada Microbiological and fermentative dynamics of tanzaniagrass and marandugrass silage using pelleted citrus pulp as an additive

Revista Brasileira de Zootecnia, 2007
O experimento foi conduzido com o objetivo de avaliar a dinâmica fermentativa e microbiológica de silagens de capins tropicais acrescidas de polpa cítrica. Os capins tanzânia (Panicum maximum cv. Tanzânia) e marandu (Brachiaria brizantha (Hochst ex.
Rogério Marchiori Coan, Ricardo Andrade Reis, Gisela Rojas Garcia, Ruben Pablo Schocken- Iturrino, Daniel de Souza Ferreira, Flávio Dutra de Resende, Felipe do Amaral Gurgel   +6 more
doaj   +1 more source