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Bacterial DNA involvement in carcinogenesis [PDF]
The incidence of cancer is high worldwide, and biological factors such as viruses and bacteria play an important role in the occurrence of cancer. Helicobacter pylori, human papillomavirus, hepatitis B viruses and other organisms have been identified as ...
Wang Yangyanqiu +5 more
doaj +4 more sources
Is human DNA enough? - Potential for bacterial DNA [PDF]
Human identification has played an important role in forensic science for the past two decades and it will continue to do so. However, there are certain types of traces, for example, low quality and low quantity of DNA, often associated with violent crimes, which cannot always be satisfactorily exploited by current techniques. So what is next?
Sarah Louise Leake
doaj +3 more sources
Bacterial DNA and osteoarthritis in dogs with patellar luxation and cranial cruciate ligament rupture [PDF]
Background and Aim: The association between bacterial DNA in stifle joints, including those with cranial cruciate ligament rupture (CCLR) and medial patellar luxation (MPL), and osteoarthritis in dogs remains elusive.
Sirun Tuek-Um +5 more
doaj +2 more sources
Plasma Bacterial DNA Load as a Potential Biomarker for the Early Detection of Colorectal Cancer: A Case–Control Study [PDF]
The gut microbiota has gained increasing attention in recent years due to its significant impact on colorectal cancer (CRC) development and progression.
Robertina Giacconi +14 more
doaj +2 more sources
Circulating bacterial DNA in cardiovascular disease. [PDF]
Cardiovascular disease (CVD) remains a global health burden despite advances in prevention and treatment. Conventional biomarkers, while effective for a number of patient groups, fail to provide personalized diagnosis and prognosis, necessitating the exploration of novel markers. Advancements in sequencing technology have unveiled the role of cell-free
Appleby S, Purcell R.
europepmc +4 more sources
Introduction The introduction of pneumococcal conjugate vaccines (PCV) into the national immunization programs (NIPs) has significantly reduced the number of pneumococcal infections.
Weronika Puzia +9 more
doaj +1 more source
DNA ligases join breaks in the phosphodiester backbone of DNA molecules and are used in many essential reactions within the cell. All DNA ligases follow the same reaction mechanism, but they may use either ATP or NAD+ as a cofactor. All Bacteria (eubacteria) contain NAD+‐dependent DNA ligases, and the uniqueness of these enzymes to Bacteria makes them ...
Wilkinson, A, Day, J, Bowater, R
openaire +3 more sources
Ribonucleotides in bacterial DNA [PDF]
In all living cells, DNA is the storage medium for genetic information. Being quite stable, DNA is well-suited for its role in storage and propagation of information, but RNA is also covalently included in DNA through various mechanisms. Recent studies also demonstrate useful aspects of including ribonucleotides in the genome during repair.
Jeremy W, Schroeder +3 more
openaire +2 more sources
Transcriptomic analysis of the genome sequenced Ligilactobacillus salivarius strain IBB3154 grown at two different temperatures (37°C vs 42°C) identified differentially expressed genes involved in metabolic pathways, osmoregulation, and surface protein ...
Patrycja Kobierecka +6 more
doaj +1 more source
Organization of DNA in a bacterial nucleoid [PDF]
It is unclear how DNA is packaged in a bacterial cell in the absence of nucleosomes. To investigate the initial level of DNA condensation in bacterial nucleoid we used in vivo DNA digestion coupled with high-throughput sequencing of the digestion-resistant fragments. To this end, we transformed E.
Tolstorukov, Michael Y. +3 more
openaire +3 more sources

