Results 11 to 20 of about 55,076 (228)

Inhibitors of Bacterial Extracellular Vesicles [PDF]

Frontiers in Microbiology, 2022
Both Gram-positive and Gram-negative bacteria can secrete extracellular vesicles (EVs), which contain numerous active substances. EVs mediate bacterial interactions with their hosts or other microbes.
Jianwei Chen, Jianwei Chen, Hongfang Zhang, Siqi Wang, Yujie Du, Bin Wei, Qiang Wu, Hong Wang, Hong Wang   +8 more
doaj   +3 more sources

Bacterial extracellular vesicle applications in cancer immunotherapy

Bioactive Materials, 2023
Cancer therapy is undergoing a paradigm shift toward immunotherapy focusing on various approaches to activate the host immune system. As research to identify appropriate immune cells and activate anti-tumor immunity continues to expand, scientists are ...
Kanika Suri, Anisha D'Souza, Di Huang, Aashray Bhavsar, Mansoor Amiji   +4 more
doaj   +3 more sources

Synthetic bacterial vesicles combined with tumour extracellular vesicles as cancer immunotherapy [PDF]

Journal of Extracellular Vesicles, 2021
Bacterial outer membrane vesicles (OMV) have gained attention as a promising new cancer vaccine platform for efficiently provoking immune responses. However, OMV induce severe toxicity by activating the innate immune system.
Kyong‐Su Park, Kristina Svennerholm, Rossella Crescitelli, Cecilia Lässer, Inta Gribonika, Jan Lötvall   +5 more
doaj   +4 more sources

Roles of bacterial extracellular vesicles in systemic diseases

Frontiers in Microbiology, 2023
Accumulating evidence suggests that in various systems, not all bidirectional microbiota–host interactions involve direct cell contact. Bacterial extracellular vesicles (BEVs) may be key participants in this interkingdom crosstalk.
Yanzhen Wang, Xinghong Luo, Xiaozhen Xiang, Chunbo Hao, Dandan Ma   +4 more
doaj   +3 more sources

Nanoplasmonic sensors for extracellular vesicles and bacterial membrane vesicles

Nano Convergence
Extracellular vesicles (EVs) are promising tools for the early diagnosis of diseases, and bacterial membrane vesicles (MVs) are especially important in health and environment monitoring.
Aparna Neettiyath, Kyungwha Chung, Wenpeng Liu, Luke P. Lee   +3 more
doaj   +3 more sources

Influences of bacterial extracellular vesicles on macrophage immune functions

Frontiers in Cellular and Infection Microbiology
Bacterial extracellular vesicles (EVs) are crucial mediators of information transfer between bacteria and host cells. Macrophages, as key effector cells in the innate immune system, have garnered widespread attention for their interactions with bacterial
Bowei Jiang, Junyun Huang
doaj   +3 more sources

Engineered Bacterial Extracellular Vesicles: Developments, Challenges, and Opportunities

Engineering
The abundant microbe-associated molecular patterns (MAMPs) and nanoscale structures of bacterial extracellular vesicles (bEVs) collectively facilitate their versatile biological activities.
Qiqiong Li, Xinyang Chen, Junhua Xie, Shaoping Nie   +3 more
doaj   +2 more sources

Maternal microbiota communicates with the fetus through microbiota-derived extracellular vesicles

Microbiome, 2023
Background Reports regarding the presence of bacteria in the fetal environment remain limited and controversial. Recently, extracellular vesicles secreted by the human gut microbiota have emerged as a novel mechanism for host-microbiota interaction.
Anna Kaisanlahti, Jenni Turunen, Nadiya Byts, Anatoliy Samoylenko, Genevieve Bart, Nikke Virtanen, Mysore V. Tejesvi, Artem Zhyvolozhnyi, Sonia Sarfraz, Sohvi Kumpula, Jenni Hekkala, Sonja Salmi, Olga Will, Johanna Korvala, Niko Paalanne, Pande Putu Erawijantari, Marko Suokas, Tuula Peñate Medina, Seppo Vainio, Oula Peñate Medina, Leo Lahti, Terhi Tapiainen, Justus Reunanen   +22 more
doaj   +1 more source

Systemically circulating bacterial extracellular vesicles: origin, fate, and function

Trends in Microbiology, 2022
Bacteria contribute to human host (patho)physiology through the production of a myriad of biomolecules enclosed in membrane vesicles [bacterial extracellular vesicles (BEVs)]. Recent research revealed that BEVs, as a functional output of bacteria, enter the systemic circulation.
An Hendrix, Olivier De Wever
openaire   +3 more sources

Extracellular Vesicles from Different Pneumococcal Serotypes Are Internalized by Macrophages and Induce Host Immune Responses

Pathogens, 2021
Bacterial extracellular vesicles are membranous ultrastructures released from the cell surface. They play important roles in the interaction between the host and the bacteria.
Alfonso Olaya-Abril, Rafael Prados-Rosales, José A. González-Reyes, Arturo Casadevall, Liise-anne Pirofski, Manuel J. Rodríguez-Ortega   +5 more
doaj   +1 more source