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Phage Therapy for Antibiotic-Resistant Bacterial Infections.
Antibiotic resistance in bacterial pathogens presents a substantial threat to the control of infectious diseases. Development of new classes of antibiotics has slowed in recent years due to pressures of cost and market profitability, and there is a ...
G. Hatfull, R. Dedrick, R. Schooley
semanticscholar +1 more source
Background Salmonella infections remain an important public health issue worldwide. Some serovars of non-typhoidal Salmonella (NTS) have been associated with bloodstream infections and gastroenteritis, especially in children in Sub-Saharan Africa with ...
Kabiru Olusegun Akinyemi+6 more
doaj +1 more source
Vimentin in Bacterial Infections [PDF]
Despite well-studied bacterial strategies to target actin to subvert the host cell cytoskeleton, thus promoting bacterial survival, replication, and dissemination, relatively little is known about the bacterial interaction with other components of the host cell cytoskeleton, including intermediate filaments (IFs). IFs have not only roles in maintaining
Tim Mak, Holger Brüggemann
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BackgroundSince the appearance of COVID-19 in January 2020, invasive bacterial infections have decreased significantly worldwide. However, alterations in age and sex distributions, clinical forms, phenotypes, and genotypes of isolates have not been ...
Ala-Eddine Deghmane, Muhamed-Kheir Taha
doaj +1 more source
Non-opportunistic bacterial infections are an important cause of morbidity and mortality for HIV-infected adults and children. Factors associated with increased risk of these include altered B- and T-cell function; altered phagocytic cell function; skin and mucous membrane defects; and use of indwelling vascular catheters, antibiotics, or cytotoxic ...
A, Kovacs, H L, Leaf, M S, Simberkoff
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Bacterial Infections in Cirrhosis [PDF]
Hospitalized patients with cirrhosis are at increased risk of developing bacterial infections, the most common being spontaneous bacterial peritonitis (SBP) and urinary tract infections. Independent predictors of the development of bacterial infections in hospitalized cirrhotic patients are poor liver synthetic function and admission for ...
Juan Rodés, Miguel Navasa
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Prevalence of and risk factors associated with latent tuberculosis infection in a Latin American region [PDF]
Tuberculosis (TB) represents a health problem in Colombia, and its control is focused on the search for contacts and treatment of TB cases underscoring the role of latent tuberculosis infection (LTBI) as a reservoir of Mycobacterium tuberculosis.
Javier Andrés Bustamante-Rengifo+6 more
doaj +2 more sources
Cefiderocol: A Review in Serious Gram-Negative Bacterial Infections
Intravenous cefiderocol (Fetroja®; Fetcroja®) is the first siderophore cephalosporin approved for the treatment of adults with serious Gram-negative bacterial infections.
Yahiya Y Syed
semanticscholar +1 more source
Haemophilus influenzae type b (Hib) seroprevalence in France: impact of vaccination schedules
Background Haemophilus influenzae serotype b (Hib) conjugate vaccine was introduced in France in 1992 as a 3 + 1 scheme at 2, 3, and 4 months (primary vaccination) with a booster at the age of 16–18 months. The vaccination was simplified in 2013 to a 2 +
Eva Hong+6 more
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Recent Evolution of Susceptibility to Beta-Lactams in Neisseria meningitidis
Beta-lactams are the main antibiotics for the treatment of invasive meningococcal disease. However, reduced susceptibility to penicillin G is increasingly reported in Neisseria meningitidis and reduced susceptibility to third-generation cephalosporines ...
Ala-Eddine Deghmane+2 more
doaj +1 more source