Results 91 to 100 of about 199,924 (308)

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Dabigatran effect on bacterial load. [PDF]

, 2019
A significant reduction in the bacterial load were seen in valves (A), myocardium (B) and spleen (C) in dabigatran (10 mg/kg/b.i.d) compared to saline treated group.
Jens Peter Goetze (316975), Christian J. Lerche (5823854), Lars J. Christophersen (6616250), Kim Thomsen (6616256), Christian Enevold (235168), Niels Høiby (117862), Peter Ø. Jensen (679559), Claus Moser (321011), Pia R. Nielsen (6616253), Henning Bundgaard (441832)   +9 more
core   +1 more source

PCR profiling of tumor-associated microorganisms in tissue of primary epithelial malignant tumors of colorectal origin: associations with key clinicopathological characteristics

Frontiers in Cellular and Infection Microbiology
IntroductionColorectal cancer is one of the most common malignancies worldwide, and microbiome research has strong potential to advance understanding of tumor biology and to support biomarker development and microbiome-targeted interventions.
Nikolay K. Shakhpazyan, Liudmila M. Mikhaleva, Nikolay K. Sadykhov, Konstantin Y. Midiber, Konstantin Y. Midiber, Roman V. Afanasev, Zarina V. Gioeva, Alexander I. Mikhalev, Arkady L. Bedzhanyan   +8 more
doaj   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Measuring nasal bacterial load and its association with otitis media [PDF]

, 2006
© 2006 Smith-Vaughan et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution ...
Leach, Amanda Jane, Halpin, Stephen, Byun, Roy, Morris, Peter Stanley, Smith-Vaughan, Heidi, Jacques, Nicholas A, Hunter, Neil, Nadkarni, Mangala   +7 more
core   +1 more source

Interventions to reduce the bacterial load in recycled broiler litter

Poultry Science, 2017
Two experiments were undertaken to evaluate the bacterial load in recycled litter between broiler flocks following addition of quicklime (T1), windrowing (T2), shallow fermentation (T3), and control (no intervention, T4). The first experiment was developed in field conditions in which the broiler houses were accompanied by 6 consecutive flocks and the ...
C S L, Vaz, D, Voss-Rech, V S, de Avila, A, Coldebella, V S, Silva   +4 more
openaire   +2 more sources

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

FEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková, Veronika Hovanová, Jiri Damborsky, Erik Sedlák   +3 more
wiley   +1 more source

Stool bacterial load in preterm infants with necrotising enterocolitis [PDF]

, 2016
Resected gut tissue in necrotising enterocolitis (NEC) has a higher bacterial load than controls. Quantitative PCR was performed on longitudinal NEC and control stool samples (n = 72).
Abdulkadir, Bashir, Skeath, Tom, Perry, J. D. (John), Berrington, Janet, Nelson, Andrew, Stewart, Christopher, Marrs, E. C. L. (Emma), Cummings, Stephen, Marrs, Emma, Perry, John, Skeath, Thomas, Embleton, Nicholas   +11 more
core   +2 more sources

Microbial Contamination of Leafy Vegetables in Porto-Novo, Republic of Benin

Journal of Food Quality and Hazards Control, 2019
Background: The vegetables provide important nutrients to human beings. Nevertheless, contaminated vegetables can cause health problems because of their microbial load.
E.J. Hougbenou Houngla, A. Gbankoto, C.D. Tossougbo Hinson   +2 more
doaj