Results 91 to 100 of about 2,339,393 (260)

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

Bacterial Load Reduction in Guheswori Sewage Treatment Plant, Kathmandu, Nepal

open access: yesJournal of College of Medical Sciences-Nepal, 2019
Background: Water sources such as lakes, ponds, river etc. have been continuously contaminated by the   micro organisms and chemicals. The former can pose a significant threat to human health.
Bikram Gautam   +2 more
doaj   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

open access: yesFEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard   +12 more
wiley   +1 more source

Abordaje de una herida por roce o fricción de categoría III, con presencia de biofilm, tras contención mecánica

open access: yesGerokomos
RESUMEN Objetivo: Reforzar y demostrar lo importante que es identificar, conocer y atender todos los factores relacionados con las biopelículas que nos encontramos en, prácticamente, todas las heridas crónicas.
Juan Ángel Hernández Ortiz   +5 more
doaj  

New techniques for wound management: A systematic review of their role in the management of chronic wounds

open access: yesArchives of Plastic Surgery, 2018
Debridement is a crucial component of wound management. Recent technologies such as hydrosurgery (Versajet), ultrasound therapy (the MIST therapy device), or plasma-mediated bipolar radio-frequency ablation therapy (Coblation) seem to represent ...
Farid Bekara   +9 more
doaj   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

open access: yesFEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana   +5 more
wiley   +1 more source

Exploring the influence of lactoferrin on wound healing and related signaling pathways: a systematic review

open access: yesFEBS Open Bio, EarlyView.
Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo   +4 more
wiley   +1 more source

Immersion of Noni Extract Improves Recovery and Reduces Bacteria in Catfish

open access: yesGrouper
Catfish is one of the superior fisheries sectors in the market, but the obstacle often faced by catfish farmers is disease attacks. One of the diseases that often attack catfish is the Aeromonas hydrophila bacteria. An alternative that can be used in the
Yusdiman W. Danial w. danial   +2 more
doaj   +1 more source

ATZ‐1 promotes DNA replication efficiency to maintain normal meiotic function

open access: yesFEBS Open Bio, EarlyView.
Absence of ATZ‐1 interferes with meiotic DNA replication and cell cycle function via CHK‐1. This causes downstream defects associated with DNA damage and genomic integrity. Taken together, this study suggests that ATZ‐1 influences DNA replication efficiency and cell cycle function to maintain normal meiotic function.
Taylin E. Gourley   +5 more
wiley   +1 more source

Antimicrobial Resistance Profiling of Non-pathogenic Microbial Flora in Curcuma longa

open access: yesJournal of Pure and Applied Microbiology
Due to poor hygiene and negligence of food safety standards, microbes find their way into the food supply chain by contaminating food ingredients and causing food-borne illnesses.
Shayan Mohd   +7 more
doaj   +1 more source

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