Results 31 to 40 of about 80,181 (224)

The Mechanism behind Bacterial Lipoprotein Release: Phenol-Soluble Modulins Mediate Toll-Like Receptor 2 Activation via Extracellular Vesicle Release from Staphylococcus aureus

mBio, 2018
The innate immune system uses Toll-like receptor (TLR) 2 to detect conserved bacterial lipoproteins of invading pathogens. The lipid anchor attaches lipoproteins to the cytoplasmic membrane and prevents their release from the bacterial cell envelope. How
Katja Schlatterer, Christian Beck, Dennis Hanzelmann, Marco Lebtig, Birgit Fehrenbacher, Martin Schaller, Patrick Ebner, Mulugeta Nega, Michael Otto, Dorothee Kretschmer, Andreas Peschel   +10 more
doaj   +1 more source

The Therapeutic Benefit of Bacterial Membrane Vesicles. [PDF]

Int J Mol Sci, 2017
The therapeutic potential of extracellular vesicles from eukaryotes has gained strong interest in recent years. However, research into the therapeutic application of their bacterial counterparts, known as bacterial membrane vesicles, is only just beginning to be appreciated.
Bitto NJ, Kaparakis-Liaskos M.
europepmc   +4 more sources

Bacterial extracellular vesicle applications in cancer immunotherapy

Bioactive Materials, 2023
Cancer therapy is undergoing a paradigm shift toward immunotherapy focusing on various approaches to activate the host immune system. As research to identify appropriate immune cells and activate anti-tumor immunity continues to expand, scientists are ...
Kanika Suri, Anisha D'Souza, Di Huang, Aashray Bhavsar, Mansoor Amiji   +4 more
doaj   +1 more source

Bacterial membrane vesicle and its diversity

Drug Delivery System, 2021
すべての生物において細胞外小胞の存在が確認されている。その細胞外小胞の形成機構とともにその役割や生理的機能が近年ますます注目されてきている。細菌の細胞外小胞の形成には細胞死が関わり、それにより細胞外小胞の多様性が生まれることが明らかになった。
Nobuhiko Nomura, Masanori Toyofuku
openaire   +2 more sources

Microbial production of lipid-protein vesicles using enveloped bacteriophage phi6

Microbial Cell Factories, 2019
Background Cystoviruses have a phospholipid envelope around their nucleocapsid. Such a feature is unique among bacterial viruses (i.e., bacteriophages) and the mechanisms of virion envelopment within a bacterial host are largely unknown.
Outi L. Lyytinen, Daria Starkova, Minna M. Poranen   +2 more
doaj   +1 more source

Roles of bacterial extracellular vesicles in systemic diseases

Frontiers in Microbiology, 2023
Accumulating evidence suggests that in various systems, not all bidirectional microbiota–host interactions involve direct cell contact. Bacterial extracellular vesicles (BEVs) may be key participants in this interkingdom crosstalk.
Yanzhen Wang, Xinghong Luo, Xiaozhen Xiang, Chunbo Hao, Dandan Ma   +4 more
doaj   +1 more source

Solution nuclear magnetic resonance spectroscopy of bacterial outer membrane proteins in natively excreted vesicles using engineered Escherichia coli

MicrobiologyOpen, 2022
Gaining structural information on membrane proteins in their native lipid environment is a long‐standing challenge in molecular biology. Instead, it is common to employ membrane mimetics, which has been shown to affect protein structure, dynamics, and ...
Mohammed Mouhib, Celestine N. Chi
doaj   +1 more source

Contribution of Membrane Vesicle to Reprogramming of Bacterial Membrane Fluidity in Pseudomonas aeruginosa

mSphere, 2022
Pseudomonas aeruginosa is an opportunistic pathogen capable of resisting environmental insults by applying various strategies, including regulating membrane fluidity and producing membrane vesicles (MVs).
Negar Mozaheb, Patrick Van Der Smissen, Tomas Opsomer, Eric Mignolet, Romano Terrasi, Adrien Paquot, Yvan Larondelle, Wim Dehaen, Giulio G. Muccioli, Marie-Paule Mingeot-Leclercq   +9 more
doaj   +1 more source

A bacterial membrane sculpting protein with BAR domain-like activity

eLife, 2021
Bin/Amphiphysin/RVS (BAR) domain proteins belong to a superfamily of coiled-coil proteins influencing membrane curvature in eukaryotes and are associated with vesicle biogenesis, vesicle-mediated protein trafficking, and intracellular signaling. Here, we
Daniel A Phillips, Lori A Zacharoff, Cheri M Hampton, Grace W Chong, Anthony P Malanoski, Lauren Ann Metskas, Shuai Xu, Lina J Bird, Brian J Eddie, Aleksandr E Miklos, Grant J Jensen, Lawrence F Drummy, Mohamed Y El-Naggar, Sarah M Glaven   +13 more
doaj   +1 more source

Proteome profiling of secreted and membrane vesicle associated proteins of an invasive and a commensal Staphylococcus haemolyticus isolate

Data in Brief, 2019
Bacterial membrane vesicles (MVs) mediate bacterial virulence by enabling secretion and long distance delivery of bacterial effector molecules. Staphylococcus haemolyticus has now been demonstrated to produce membrane vesicles (MVs).
Jorunn Pauline Cavanagh, Fatemeh Askarian, Maria Pain, Jack-Ansgar Bruun, Ilona Urbarova, Sun Nyunt Wai, Frank Schmidt, Mona Johannessen   +7 more
doaj   +1 more source