Results 1 to 10 of about 172,115 (282)

BACTERIAL OUTER MEMBRANE VESICLES AND VACCINE APPLICATIONS [PDF]

Frontiers in Immunology, 2014
Vaccines based on outer membrane vesicles (OMV) were developed more than 20 years ago against Neisseria meningitidis serogroup B. These nano-sized structures exhibit remarkable potential for immunomodulation of immune responses and delivery of self ...
Reinaldo eAcevedo, Sonsire eFernandez, Caridad eZayas, Armando eAcosta, Maria Elena Sarmiento, Valerie A Ferro, Einar eRosenqvist, Concepcion eCampa, Daniel eCardoso, Luis eGarcia, Jose Luis Perez   +10 more
doaj   +5 more sources

Bacterial outer membrane vesicle-based cancer nanovaccines

Cancer Biology & Medicine, 2022
Tumor vaccines, a type of personalized tumor immunotherapy, have developed rapidly in recent decades. These vaccines evoke tumor antigen-specific T cells to achieve immune recognition and killing of tumor cells.
Xiaoyu Gao, Qingqing Feng, Jing Wang, Xiao Zhao   +3 more
doaj   +3 more sources

Contribution of bacterial outer membrane vesicles to innate bacterial defense [PDF]

BMC Microbiology, 2011
Background Outer membrane vesicles (OMVs) are constitutively produced by Gram-negative bacteria throughout growth and have proposed roles in virulence, inflammation, and the response to envelope stress.
Manning Andrew J, Kuehn Meta J
doaj   +3 more sources

Engineering Planar Gram-Negative Outer Membrane Mimics Using Bacterial Outer Membrane Vesicles. [PDF]

Langmuir, 2023
AbstractAntibiotic resistance is a major challenge in modern medicine. The unique double membrane structure of gram-negative bacteria limits the efficacy of many existing antibiotics and adds complexity to antibiotic development by limiting transport of antibiotics to the bacterial cytosol. New methods to mimic this barrier would enable high-throughput
Singh AN, Wu M, Ye TT, Brown AC, Wittenberg NJ.   +4 more
europepmc   +4 more sources

Bacterial outer membrane vesicle nanorobot. [PDF]

Proc Natl Acad Sci U S A
Autonomous nanorobots represent an advanced tool for precision therapy to improve therapeutic efficacy. However, current nanorobotic designs primarily rely on inorganic materials with compromised biocompatibility and limited biological functions. Here, we introduce enzyme-powered bacterial outer membrane vesicle (OMV) nanorobots. The immobilized urease
Tang S, Tang D, Zhou H, Li Y, Zhou D, Peng X, Ren C, Su Y, Zhang S, Zheng H, Wan F, Yoo J, Han H, Ma X, Gao W, Wu S.   +15 more
europepmc   +4 more sources

Outer membrane vesicles: A bacterial-derived vaccination system

Frontiers in Microbiology, 2022
Outer membrane vesicles (OMVs) are non-living spherical nanostructures that derive from the cell envelope of Gram-negative bacteria. OMVs are important in bacterial pathogenesis, cell-to-cell communication, horizontal gene transfer, quorum sensing, and ...
Linda A. Lieberman
doaj   +3 more sources

Bacterial Outer Membrane Vesicles Induce Plant Immune Responses [PDF]

Molecular Plant-Microbe Interactions, 2016
Gram-negative bacteria continuously pinch off portions of their outer membrane, releasing membrane vesicles. These outer membrane vesicles (OMVs) are involved in multiple processes including cell-to-cell communication, biofilm formation, stress tolerance,
Ofir Bahar, Gideon Mordukhovich, Dee Dee Luu, Benjamin Schwessinger, Arsalan Daudi, Anna Kristina Jehle, Georg Felix, Pamela C. Ronald   +7 more
doaj   +4 more sources

Bacterial outer membrane vesicles in the fight against cancer [PDF]

Chinese Medical Journal
. Bacterial outer membrane vesicles (OMVs) are diminutive vesicles naturally released by Gram-negative bacteria. These vesicles possess distinctive characteristics that attract attention for their potential use in drug administration and immunotherapy in
Yiming Meng, Cuicui Kong, Yushu Ma, Jing Sun, Guirong Zhang, Xiangxiang Pan   +5 more
doaj   +2 more sources

Commensal bacterial outer membrane protein A induces interleukin-22 production [PDF]

Cell Reports
Summary: Interleukin (IL)-22 promotes host-microbiota homeostasis. We sought to identify microbiota metabolite(s) that drive intestinal IL-22 production.
Yanling Wang, Vu L. Ngo, Jun Zou, Andrew T. Gewirtz   +3 more
doaj   +2 more sources

A Barrier to Entry: Examining the Bacterial Outer Membrane and Antibiotic Resistance

Applied Sciences, 2023
Gram-negative bacteria can resist antibiotics by changing the permeability via their outer membrane. These bacteria have a complex cell envelope that incorporates an outer membrane separating the periplasm from the external environment.
Ishan Ghai
doaj   +1 more source