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Biogenesis of the Gram-negative bacterial outer membrane [PDF]
Current Opinion in Microbiology, 2004 Gram-negative bacteria are bounded by two membranes. The outer membrane consists of phospholipids, lipopolysaccharides, lipoproteins and integral outer membrane proteins, all of which are synthesized in the cytoplasm. Recently, much progress has been made in the elucidation of the mechanisms of transport of these molecules over the inner membrane ...
Martine P. Bos, Jan Tommassen
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Bacterial outer membrane vesicle nanorobot. [PDF]
Proc Natl Acad Sci U S AAutonomous nanorobots represent an advanced tool for precision therapy to improve therapeutic efficacy. However, current nanorobotic designs primarily rely on inorganic materials with compromised biocompatibility and limited biological functions. Here, we introduce enzyme-powered bacterial outer membrane vesicle (OMV) nanorobots. The immobilized urease
Tang S +15 more
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Reply to: Antibiotics and hexagonal order in the bacterial outer membrane. [PDF]
Nat Commun, 2023 ISSN:2041 ...
Manioglu S +9 more
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Protein oligomerization in the bacterial outer membrane (Review) [PDF]
Molecular Membrane Biology, 2009 The formation of homo-oligomeric assemblies is a well-established characteristic of many soluble proteins and enzymes. Oligomerization has been shown to increase protein stability, allow allosteric cooperativity, shape reaction compartments and provide multivalent interaction sites in soluble proteins. In comparison, our understanding of the prevalence
Guoyu Meng +4 more
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Molecular basis of bacterial outer membrane permeability. [PDF]
Microbiological Reviews, 1985 Hiroshi Nikaido, Martti Vaara
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Antibiotics and hexagonal order in the bacterial outer membrane. [PDF]
Nat Commun, 2023 Benn G +3 more
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Entry and exit of bacterial outer membrane proteins [PDF]
Trends in Microbiology, 2015 The sites of new outer membrane protein (OMP) deposition and the fate of pre-existing OMPs are still enigmatic despite numerous concerted efforts. Rassam et al. identified mid-cell regions as the primary entry points for new OMP insertion in clusters, driving the pre-existing OMP clusters towards cell poles for long-term storage.
Rajeev Misra
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Bacterial Outer Membrane Vesicles and Vaccine Applications [PDF]
Frontiers in Immunology, 2014 Vaccines based on outer membrane vesicles (OMV) were developed more than 20 years ago against Neisseria meningitidis serogroup B. These nano-sized structures exhibit remarkable potential for immunomodulation of immune responses and delivery of meningococcal antigens or unrelated antigens incorporated into the vesicle structure.
Acevedo, Reinaldo +10 more
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Langmuir Monolayers of Bacterial Outer Membranes [PDF]
Biophysical Journal, 2013 The increase of Gram-negative bacteria super-resistant to antibiotics is a major problem in medicine. These bacteria possess a double membrane system, with the external leaflet of the outer membrane composed of lipopolyssaccharides (LPS) that act as the first barrier to drugs.
Hiroshi Nikaido +3 more
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Bacterial outer membrane constriction [PDF]
Molecular Microbiology, 2018 SummaryThe outer membrane of Gram‐negative bacteria is a crucial permeability barrier allowing the cells to survive a myriad of toxic compounds, including many antibiotics. This innate form of antibiotic resistance is compounded by the evolution of more active mechanisms of resistance such as efflux pumps, reducing the already limited number of ...
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