Results 11 to 20 of about 330,291 (296)

Bacterial outer membrane vesicle nanorobot. [PDF]

Proc Natl Acad Sci U S A
Autonomous nanorobots represent an advanced tool for precision therapy to improve therapeutic efficacy. However, current nanorobotic designs primarily rely on inorganic materials with compromised biocompatibility and limited biological functions. Here, we introduce enzyme-powered bacterial outer membrane vesicle (OMV) nanorobots. The immobilized urease
Tang S, Tang D, Zhou H, Li Y, Zhou D, Peng X, Ren C, Su Y, Zhang S, Zheng H, Wan F, Yoo J, Han H, Ma X, Gao W, Wu S.   +15 more
europepmc   +4 more sources

Bacterial Outer Membrane Vesicles as Antibiotic Delivery Vehicles

Frontiers in Immunology, 2021
Bacterial outer membrane vesicles (OMVs) are nanometer-scale, spherical vehicles released by Gram-negative bacteria into their surroundings throughout growth.
Shannon M. Collins, Angela C. Brown
doaj   +1 more source

Outer membrane vesicles: A bacterial-derived vaccination system

Frontiers in Microbiology, 2022
Outer membrane vesicles (OMVs) are non-living spherical nanostructures that derive from the cell envelope of Gram-negative bacteria. OMVs are important in bacterial pathogenesis, cell-to-cell communication, horizontal gene transfer, quorum sensing, and ...
Linda A. Lieberman
doaj   +1 more source

The outer membrane phospholipase A is essential for membrane integrity and type III secretion in Shigella flexneri [PDF]

Open Biology, 2016
Outer membrane phospholipase A (OMPLA) is an enzyme located in the outer membrane of Gram-negative bacteria. OMPLA exhibits broad substrate specificity, and some of its substrates are located in the cellular envelope.
Xia Wang, Feng Jiang, Jianhua Zheng, Lihong Chen, Jie Dong, Lilian Sun, Yafang Zhu, Bo Liu, Jian Yang, Guowei Yang, Qi Jin   +10 more
doaj   +1 more source

Murepavadin induces envelope stress response and enhances the killing efficacies of β-lactam antibiotics by impairing the outer membrane integrity of Pseudomonas aeruginosa

Microbiology Spectrum, 2023
Pseudomonas aeruginosa is a ubiquitous opportunistic pathogen that can cause a variety of acute and chronic infections. The bacterium is highly resistant to numerous antibiotics.
Xiaoya Wei, Jiacong Gao, Congjuan Xu, Xiaolei Pan, Yongxin Jin, Fang Bai, Zhihui Cheng, Iain L. Lamont, Daniel Pletzer, Weihui Wu   +9 more
doaj   +1 more source

Solute channels of the outer membrane: from bacteria to chloroplasts [PDF]

, 2007
Chloroplasts, unique organelles of plants, originated from endosymbiosis of an ancestor of today's cyanobacteria with a mitochondria-containing host cell. It is assumed that the outer envelope membrane, which delimits the chloroplast from the surrounding
Aljamal J.A., Benz R., Blumenthal A., Drea S.C., Fischer K., Murcha M.W., Pilsl H., Umeda H., Zizi M.   +8 more
core   +1 more source

Bacterial outer membrane constriction [PDF]

Molecular Microbiology, 2018
SummaryThe outer membrane of Gram‐negative bacteria is a crucial permeability barrier allowing the cells to survive a myriad of toxic compounds, including many antibiotics. This innate form of antibiotic resistance is compounded by the evolution of more active mechanisms of resistance such as efflux pumps, reducing the already limited number of ...
openaire   +3 more sources

Lipopolysaccharide Transport to the Bacterial Outer Membrane in Spheroplasts [PDF]

Journal of Biological Chemistry, 2005
The mechanism of lipopolysaccharide (LPS) transport in Gram-negative bacteria from the inner membrane to the outer membrane is largely unknown. Here, we investigated the possibility that LPS transport proceeds via a soluble intermediate associated with a periplasmic chaperone analogous to the Lol-dependent transport mechanism of lipoproteins.
Tefsen, B., Geurtsen, J., Beckers, F., Tommassen, J., Cock, H.   +4 more
openaire   +4 more sources

The porin and the permeating antibiotic: A selective diffusion barrier in gram-negative bacteria [PDF]

, 2008
Gram-negative bacteria are responsible for a large proportion of antibiotic resistant bacterial diseases. These bacteria have a complex cell envelope that comprises an outer membrane and an inner membrane that delimit the periplasm.
A Baslé, A Baslé, A Bryskier, A Davin-Regli, A Davin-Régli, A Doménech-Sánchez, A Doménech-Sánchez, A Loli, A Mena, A Mena, A Prilipov, A Thiolas, A Thiolas, AA Medeiros, AH Delcour, AM Berezhkovskii, AM Giuliodori, AS Low, C Bornet, C Bornet, C Bosi, C Danelon, C Danelon, C Rodrigues, C Sheridan, Chloë E. James, D Jeanteur, D Szabó, DJ Wolter, E Dé, E Elliott, E Sugawara, EM Nestorovich, EM Nestorovich, F Yoshimura, FM Kaczmarek, G Schwarz, GA Jacoby, GE Schulz, H Nikaido, H Nikaido, H Nikaido, H Samartzidou, H Samartzidou, J Bredin, J Chevalier, J Chevalier, J-M Pagès, JC Cai, Jean-Marie Pagès, JM Bower, K Poole, L Kullman, L Martínez-Martínez, LB Rice, LJ Piddock, LP Randall, M Ceccarelli, M Guillier, M Luckey, M Malléa, M Olesky, M Olesky, M Viveiros, MA Kohanski, Mathias Winterhalter, MM Ochs, N El Amin, P Valentin-Hansen, R Dutzler, R Iyer, R Iyer, R Koebnik, RE Hancock, RN Charrel, S Biswas, S Blot, S Hernández-Allés, S Hernández-Allés, S Nekolla, S Vidal, S Vidal, SF Epp, SM Bezrukov, SM Bezrukov, SR Norrby, SW Cowan, T Ferenci, T Mach, UO Hasdemir, V Simonet, V Simonet, WL Veal, WM Shafer, WR Bauer, XZ Li   +95 more
core   +1 more source

Biogenesis of the Gram-Negative Bacterial Outer Membrane [PDF]

Annual Review of Microbiology, 2007
The cell envelope of gram-negative bacteria consists of two membranes, the inner and the outer membrane, that are separated by the periplasm. The outer membrane consists of phospholipids, lipopolysaccharides, integral membrane proteins, and lipoproteins.
Bos, M.P., Robert, V.M.V., Tommassen, J.P.M.   +2 more
openaire   +3 more sources