Results 11 to 20 of about 158,347 (278)

Contribution of bacterial outer membrane vesicles to innate bacterial defense [PDF]

open access: yesBMC Microbiology, 2011
Outer membrane vesicles (OMVs) are constitutively produced by Gram-negative bacteria throughout growth and have proposed roles in virulence, inflammation, and the response to envelope stress. Here we investigate outer membrane vesiculation as a bacterial mechanism for immediate short-term protection against outer membrane acting stressors ...
Manning, Andrew J, Kuehn, Meta J
openaire   +5 more sources

Bacterial Outer Membrane Vesicles as Antibiotic Delivery Vehicles [PDF]

open access: yesFrontiers in Immunology, 2021
Bacterial outer membrane vesicles (OMVs) are nanometer-scale, spherical vehicles released by Gram-negative bacteria into their surroundings throughout growth. These OMVs have been demonstrated to play key roles in pathogenesis by delivering certain biomolecules to host cells, including toxins and other virulence factors.
Angela C. Brown, Shannon M. Collins
openaire   +4 more sources

Outer Membrane Vesicles as Mediators of Plant–Bacterial Interactions

open access: yesFrontiers in Microbiology, 2022
Plants have co-evolved with diverse microorganisms that have developed different mechanisms of direct and indirect interactions with their host. Recently, greater attention has been paid to a direct “message” delivery pathway from bacteria to plants, mediated by the outer membrane vesicles (OMVs).
Rudnicka, Małgorzata   +5 more
openaire   +6 more sources

Bacterial outer membrane vesicle-based cancer nanovaccines

open access: yesCancer Biology & Medicine, 2022
Tumor vaccines, a type of personalized tumor immunotherapy, have developed rapidly in recent decades. These vaccines evoke tumor antigen-specific T cells to achieve immune recognition and killing of tumor cells.
Xiaoyu Gao   +3 more
doaj   +1 more source

A Barrier to Entry: Examining the Bacterial Outer Membrane and Antibiotic Resistance

open access: yesApplied Sciences, 2023
Gram-negative bacteria can resist antibiotics by changing the permeability via their outer membrane. These bacteria have a complex cell envelope that incorporates an outer membrane separating the periplasm from the external environment.
Ishan Ghai
doaj   +1 more source

A small molecule that disrupts S. Typhimurium membrane voltage without cell lysis reduces bacterial colonization of mice.

open access: yesPLoS Pathogens, 2022
As pathogenic bacteria become increasingly resistant to antibiotics, antimicrobials with mechanisms of action distinct from current clinical antibiotics are needed.
Jamie L Dombach   +5 more
doaj   +1 more source

Molecular imaging of bacterial outer membrane vesicles based on bacterial surface display. [PDF]

open access: yesSci Rep, 2023
The important roles of bacterial outer membrane vesicles (OMVs) in various diseases and their emergence as a promising platform for vaccine development and targeted drug delivery necessitates the development of imaging techniques suitable for quantifying
Szöllősi D   +24 more
europepmc   +2 more sources

The outer membrane phospholipase A is essential for membrane integrity and type III secretion in Shigella flexneri [PDF]

open access: yesOpen Biology, 2016
Outer membrane phospholipase A (OMPLA) is an enzyme located in the outer membrane of Gram-negative bacteria. OMPLA exhibits broad substrate specificity, and some of its substrates are located in the cellular envelope.
Xia Wang   +10 more
doaj   +1 more source

Outer membrane vesicles: A bacterial-derived vaccination system

open access: yesFrontiers in Microbiology, 2022
Outer membrane vesicles (OMVs) are non-living spherical nanostructures that derive from the cell envelope of Gram-negative bacteria. OMVs are important in bacterial pathogenesis, cell-to-cell communication, horizontal gene transfer, quorum sensing, and ...
Linda A. Lieberman
doaj   +1 more source

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