Results 11 to 20 of about 465,571 (364)

A Barrier to Entry: Examining the Bacterial Outer Membrane and Antibiotic Resistance

open access: yesApplied Sciences, 2023
Gram-negative bacteria can resist antibiotics by changing the permeability via their outer membrane. These bacteria have a complex cell envelope that incorporates an outer membrane separating the periplasm from the external environment.
Ishan Ghai
doaj   +2 more sources

Biomimetic Lipopolysaccharide‐Free Bacterial Outer Membrane‐Functionalized Nanoparticles for Brain‐Targeted Drug Delivery

open access: yesAdvanced Science, 2022
The blood–brain barrier (BBB) severely blocks the intracranial accumulation of most systemic drugs. Inspired by the contribution of the bacterial outer membrane to Escherichia coli K1 (EC‐K1) binding to and invasion of BBB endothelial cells in bacterial ...
Haiyan Chen   +10 more
doaj   +2 more sources

Engineered Bacterial Outer Membrane Vesicles as Multifunctional Delivery Platforms

open access: yesFrontiers in Materials, 2020
Outer membrane vesicles (OMVs) are valued for their unique, convenient, and amendable functions. They are flexible, controllable nanoparticles, which can be modified in different ways, for use in a wide array of applications like adjuvants, vaccines ...
Ruizhen Li, Qiong Liu, Qiong Liu
doaj   +2 more sources

Molecular Basis of Bacterial Outer Membrane Permeability Revisited [PDF]

open access: greenMicrobiology and Molecular Biology Reviews, 2003
Hiroshi Nikaido
openalex   +2 more sources

Commensal bacterial outer membrane protein A induces interleukin-22 production [PDF]

open access: yesCell Reports
Summary: Interleukin (IL)-22 promotes host-microbiota homeostasis. We sought to identify microbiota metabolite(s) that drive intestinal IL-22 production.
Yanling Wang   +3 more
doaj   +2 more sources

A Bilayer-Couple Model of Bacterial Outer Membrane Vesicle Biogenesis

open access: goldmBio, 2012
Gram-negative bacteria naturally produce outer membrane vesicles (OMVs) that arise through bulging and pinching off of the outer membrane. OMVs have several biological functions for bacteria, most notably as trafficking vehicles for toxins ...
Jeffrey W. Schertzer, Marvin Whiteley
doaj   +2 more sources

Entry and exit of bacterial outer membrane proteins [PDF]

open access: greenTrends in Microbiology, 2015
The sites of new outer membrane protein (OMP) deposition and the fate of pre-existing OMPs are still enigmatic despite numerous concerted efforts. Rassam et al. identified mid-cell regions as the primary entry points for new OMP insertion in clusters, driving the pre-existing OMP clusters towards cell poles for long-term storage.
Rajeev Misra
openalex   +4 more sources

Bacterial outer membrane vesicle-based cancer nanovaccines

open access: yesCancer Biology & Medicine, 2022
Tumor vaccines, a type of personalized tumor immunotherapy, have developed rapidly in recent decades. These vaccines evoke tumor antigen-specific T cells to achieve immune recognition and killing of tumor cells.
Xiaoyu Gao   +3 more
doaj   +1 more source

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