Results 191 to 200 of about 172,115 (282)

DR5 Governs Compound Exocytosis in Colonic Goblet Cells via TATA‐Box Binding Protein‐Dependent Bestrophin‐2 Transcriptional Regulation

Advanced Science, EarlyView.
DR5 knockout exhibits a thinner colonic mucus layer, leading to mild dysbiosis, increased susceptibility to Citrobacter rodentium invasion, and exacerbated epithelial injury. Mechanistically, DR5 binds transcription factor TBP, which regulates the expression of gene Best2 via its promoter.
Ying Wang, Xinyun Li, Yong Wang, Chuhe Yang, Xiaopei Gao, Ke Zhu, Yihang Ren, Jingxin Li, Chuanyong Liu, Bing Xue   +9 more
wiley   +1 more source

Primary role of the Tol-Pal complex in bacterial outer membrane lipid homeostasis. [PDF]

Nat Commun
Tan WB, Chng SS.
europepmc   +1 more source

Hydrogel‐Coated Foam Evaporator Achieving Four‐In‐One Benefits for Efficient and Stable Solar‐Driven Water Purification

Advanced Science, EarlyView.
This study introduces a universal strategy for foam‐based solar evaporators, leveraging the unique advantages of hydrogel materials to effectively reduce evaporation enthalpy. At the same time, it addresses challenges such as the need for pore formation in hydrogels, water‐induced swelling, and the detachment of photothermal materials, achieving “four ...
Lele Li, Yanhong Dong, Shu Liu, Xingmin Du, Diandian Yu, Jie Wen, Chenxi Wang, Qian Sun, Bing Liu, Tao Wu, Jiahui Yu   +10 more
wiley   +1 more source

The Mitochondrial Porin, VDAC, Has Retained the Ability to Be Assembled in the Bacterial Outer Membrane [PDF]

, 2009
Dirk Walther, Martine P. Bos, Doron Rapaport, Jan Tommassen   +3 more
openalex   +1 more source

Engineering CRISPR System-Based Bacterial Outer Membrane Vesicle Potentiates T Cell Immunity for Enhanced Cancer Immunotherapy. [PDF]

Adv Mater
Wang H, Zhan H, Pan B, Zeng L, Chen Z, Liu S, Zhang Q, Hong X, Lu J, Lin X, Zhao X, Lai J, Jie K, Li Y, Zhong J, Peng S, Chen S, Chen C, Zhong W, Wu S, Pan Y, Lin T, Chen X.   +22 more
europepmc   +1 more source

Thermally Gated Dual‐Cascade Nanozyme for Enhanced Mild‐Temperature Photothermal Therapy

Advanced Science, EarlyView.
A thermo‐responsive cascade nanozyme (Ru‐GOx‐PNN) synergistically enhances mild photothermal therapy by dual suppression of HSP70 through ROS‐induced lipid peroxidation and ATP depletion. This intelligent system effectively overcomes thermotolerance and amplifies apoptosis, offering a safe and precise strategy for tumor treatment.
Shuyu Wang, Shenghui Wang, Mengyuan Cao, Lulu Wang, Wei Jiang, Xiyun Yan, Ying Liu, Bing Jiang   +7 more
wiley   +1 more source

Model of mouth-to-mouth transfer of bacterial lipoproteins through inner membrane LolC, periplasmic LolA, and outer membrane LolB

, 2009
Suguru Okuda, Hajime Tokuda
openalex   +1 more source

Photothermal–Immunomodulatory Hydrogel Reinforced by Ti3C2/ZnAl‐LDH Nanoplatform for Eradicating MRSA and Promoting Diabetic Wound Healing

Advanced Science, EarlyView.
A NETs‐inspired Ti3C2/LDH hydrogel integrates trapping, ROS boosting, and M2‐immunomodulation for MRSA‐infected wound repair. ABSTRACT MRSA infections give rise to chronic cutaneous and advance into profound tissue invasions, including osteomyelitis and sepsis—conditions for which existing clinical interventions offer only limited efficacy. The utility
Qiang Shi, Renliang Zhao, Jia Wang, Zhenchen Xiong, Xiangtian Deng, Cheng Zheng, Wenzhi Zhang   +6 more
wiley   +1 more source

Chimeric Nanozyme Bacterial Outer Membrane Vesicles Reprograming Tumor Microenvironment for Safe and Efficient Anticancer Therapy. [PDF]

Adv Sci (Weinh)
Zhang F, Li Q, Dai H, Li W, Chen X, Wu H, Lu S, Luo R, Li F, Lu G, Yu J, Mei L.   +11 more
europepmc   +1 more source

Biomimetic Nanomedicine for Senescence‐Modulated Immune Activation Enhances Immunotherapy Efficacy in Hepatocellular Carcinoma

Advanced Science, EarlyView.
A multifunctional mPDZM nanoplatform is developed in this study. mPDZM integrates chemotherapy‐induced senescence, selective senolysis, and STING‐mediated immune activation. mPDZM effectively clears senescent tumor cells, remodels the tumor immune microenvironment, and enhances antitumor T‐cell responses.
Shiji Fang, Liyun Zheng, Bin Lin, Jiale Chen, Dehai Hou, Yiming Ding, Mengzhu Han, Pan Qin, Mengyuan Wang, Xiaoju Guo, Yeyu Zhang, Gaofeng Shu, Fazong Wu, Jianfei Tu, Minjiang Chen, Zhongwei Zhao, Zhuang Liu, Jiansong Ji   +17 more
wiley   +1 more source