Engineered Bacterial Outer Membrane Vesicles Hitchhiking on Neutrophils for Antibody Drug Delivery to Enhance Postoperative Immune Checkpoint Therapy. [PDF]
Guan M+15 more
europepmc +1 more source
Covalent organic framework (COF)‐reuterin induces trained immunity in tumor‐associated macrophages, promoting the generation of nitric oxide and reactive oxygen species, thereby enhancing the antitumor immune response. Additionally, COF‐Reuterin directly kills tumor cells while simultaneously eradicating pathogenic intratumoural bacteria.
Jian‐Gang Zhang+8 more
wiley +1 more source
Small RNA Regulation of TolC, the Outer Membrane Component of Bacterial Multidrug Transporters [PDF]
Ashley Parker, Susan Gottesman
openalex +1 more source
Genetic Impacts on the Structure and Mechanics of Cellulose Made by Bacteria
A genetic mutation in a protease of a cellulose‐overproducing evolved bacterium significantly affects the proteome, structure, and mechanical properties of bio‐fabricated cellulose pellicles. By overexpressing synthase proteins that build the cellulose‐forming biological machinery of the cell, the evolved bacterium generates dense, stiff, and strong ...
Julie M. Laurent+8 more
wiley +1 more source
Viral Mimetic Bacterial Outer Membrane Vesicles for Targeting Angiotensin-Converting Enzyme 2. [PDF]
Ahn G+6 more
europepmc +1 more source
Gram-Negative Bacterial Outer Membrane Vesicles Inhibit Growth of Multidrug-Resistant Organisms and Induce Wound-Healing Cytokines [PDF]
Sarah M. Baker+2 more
openalex +1 more source
Developing Biomaterial‐Based mRNA Delivery System for Lung Disease Treatment
Schematic illustration of biomaterial delivery mRNA for the treatment of lung diseases. Abstract Lung disease remains a persistent global health challenge. Advances in medical research have led to innovative strategies to combat these conditions, with biomaterials emerging as a promising platform for targeted drug delivery.
Qiancheng Gu+7 more
wiley +1 more source
Bacterial Minicell‐Based Biohybrid Sub‐micron Swimmers for Targeted Cargo Delivery
Bacterial minicells, vesicles derived from engineered E. coli, offer promising sub‐micron scale biohybrid swimmers for targeted cargo delivery. Purified with over 99% efficiency while retaining motility, they are functionalized with MNPs for controlled movement.
Saadet Fatma Baltaci+4 more
wiley +1 more source
Structural basis for alginate secretion across the bacterial outer membrane
John C. Whitney+10 more
openalex +1 more source