Results 291 to 300 of about 328,822 (337)

Advances in understanding bacterial outer-membrane biogenesis

Nature Reviews Microbiology, 2006
The outer membrane of gram-negative bacteria such as Escherichia coli serves as a protective barrier that controls the influx and efflux of solutes. This allows the bacteria to inhabit several different, and often hostile, environments. The assembly of the E.
Natividad, Ruiz, Daniel, Kahne, Thomas J, Silhavy   +2 more
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Transport across the bacterial outer membrane

Journal of Bioenergetics and Biomembranes, 1993
Diffusion of small molecules across the outer membrane of gram-negative bacteria may occur through protein channels and through lipid bilayer domains. Among protein channels, many examples of trimeric porins, which produce water-filled diffusion channels, are known.
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Secretion across the bacterial outer membrane

Trends in Genetics, 1992
Many bacteria secrete extracellular proteins such as hydrolytic enzymes or toxins. In Gram-negative bacteria, secreted proteins must cross the two membranes that constitute the cell envelope. Recent studies have identified several specific secretion systems that can be classified in three distinct pathways, and related systems have been discovered in a
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Monoclonal Antibodies Against Bacterial Outer Membrane Antigens

1985
Monoclonal antibodies have proved to be highly specific tools for defining the antigenic epitopes of Pseudomonas aeruginosa outer membrane macromolecules. In this article we have highlighted the use of monoclonal antibodies in the study of lipopolysaccharide heterogeneity and in particular have demonstrated that single monoclonal antibodies can ...
R E, Hancock, L M, Mutharia
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Bacterial Nanobioreactors–Directing Enzyme Packaging into Bacterial Outer Membrane Vesicles

ACS Applied Materials & Interfaces, 2015
All bacteria shed outer membrane vesicles (OMVs) loaded with a diverse array of small molecules, proteins, and genetic cargo. In this study we sought to hijack the bacterial cell export pathway to simultaneously produce, package, and release an active enzyme, phosphotriesterase (PTE). To accomplish this goal the SpyCatcher/SpyTag (SC/ST) bioconjugation
Nathan J, Alves, Kendrick B, Turner, Michael A, Daniele, Eunkeu, Oh, Igor L, Medintz, Scott A, Walper   +5 more
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Modified bacterial outer membrane vesicles induce autoantibodies for tumor therapy.

Acta Biomaterialia, 2020
Using monoclonal antibodies to block tumor angiogenesis has yielded effective antitumor effects. However, this treatment method has long cycles and is very expensive; therefore, its long-term and extensive application is limited.
Weiwei Huang, Congyan Shu, Liangqun Hua, Yilin Zhao, Hanghang Xie, Jia-long Qi, Fulan Gao, Ruiyu Gao, Yongjun Chen, Qishu Zhang, Weiran Li, Mingcui Yuan, Chao Ye, Yanbing Ma   +13 more
semanticscholar   +1 more source

Porin from Bacterial and Mitochondrial Outer Membrane

Critical Reviews in Biochemistry, 1985
The outer membrane of gram-negative bacteria acts as a molecular filter with defined exclusion limit for hydrophilic substances. The exclusion limit is dependent on the type of bacteria and has for enteric bacteria like Escherichia coli and Salmonella typhimurium a value between 600 and 800 Daltons, whereas molecules with molecular weights up to 6000 ...
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Construction of nanoantennas on the bacterial outer membrane

Chem. Commun., 2014
A simple and highly sensitive detection of pathogenic bacteria is achieved by utilizing gold nanoparticles as an optical antenna.
Hiroshi, Shiigi, Maho, Fukuda, Takatoshi, Tono, Kaori, Takada, Tomoyuki, Okada, Le Quynh, Dung, Yu, Hatsuoka, Takamasa, Kinoshita, Masahiro, Takai, Shiho, Tokonami, Hidenobu, Nakao, Tomoaki, Nishino, Yojiro, Yamamoto, Tsutomu, Nagaoka   +13 more
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Protein oligomerization in the bacterial outer membrane (Review)

Molecular Membrane Biology, 2009
The formation of homo-oligomeric assemblies is a well-established characteristic of many soluble proteins and enzymes. Oligomerization has been shown to increase protein stability, allow allosteric cooperativity, shape reaction compartments and provide multivalent interaction sites in soluble proteins. In comparison, our understanding of the prevalence
Guoyu, Meng, Rémi, Fronzes, Vidya, Chandran, Han, Remaut, Gabriel, Waksman   +4 more
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Proteomics in gram‐negative bacterial outer membrane vesicles

Mass Spectrometry Reviews, 2008
AbstractGram‐negative bacteria constitutively secrete outer membrane vesicles (OMVs) into the extracellular milieu. Recent research in this area has revealed that OMVs may act as intercellular communicasomes in polyspecies communities by enhancing bacterial survival and pathogenesis in hosts.
Lee, EY, Choi, DS, Kim, KP, Gho, YS
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