Results 31 to 40 of about 465,571 (364)

Langmuir Monolayers of Bacterial Outer Membranes [PDF]

Biophysical Journal, 2013
The increase of Gram-negative bacteria super-resistant to antibiotics is a major problem in medicine. These bacteria possess a double membrane system, with the external leaflet of the outer membrane composed of lipopolyssaccharides (LPS) that act as the first barrier to drugs.
Hiroshi Nikaido, Tonya L. Kuhl, Ronnald N. Zuckermann, Thatyane M. Nobre   +3 more
openaire   +2 more sources

Cellular Nanodiscs Made from Bacterial Outer Membrane as a Platform for Antibacterial Vaccination.

ACS Nano, 2022
Vaccination has become an increasingly attractive strategy for protecting against antibiotic-resistant infections. Nanovaccines based on the outer membrane from Gram-negative bacteria are appealing due to their multiantigenic nature and inherent ...
Ilkoo Noh, Zhongyuan Guo, Jiarong Zhou, Weiwei Gao, Ronnie H. Fang, Liangfang Zhang   +5 more
semanticscholar   +1 more source

Bacterial outer membrane vesicles and their functionalization as vehicles for bioimaging, diagnosis and therapy

Materials Advances, 2022
Bacterial outer membrane vesicles (OMVs) are spherical nanostructures spontaneously released from Gram-negative bacteria. Natural OMVs that are abundant with lipopolysaccharides, phospholipids, proteins, and nucleic acids have diverse biological ...
Kai Xue, Lu Wang, Jinyao Liu
semanticscholar   +1 more source

The porin and the permeating antibiotic: A selective diffusion barrier in gram-negative bacteria [PDF]

, 2008
Gram-negative bacteria are responsible for a large proportion of antibiotic resistant bacterial diseases. These bacteria have a complex cell envelope that comprises an outer membrane and an inner membrane that delimit the periplasm.
A Baslé, A Baslé, A Bryskier, A Davin-Regli, A Davin-Régli, A Doménech-Sánchez, A Doménech-Sánchez, A Loli, A Mena, A Mena, A Prilipov, A Thiolas, A Thiolas, AA Medeiros, AH Delcour, AM Berezhkovskii, AM Giuliodori, AS Low, C Bornet, C Bornet, C Bosi, C Danelon, C Danelon, C Rodrigues, C Sheridan, Chloë E. James, D Jeanteur, D Szabó, DJ Wolter, E Dé, E Elliott, E Sugawara, EM Nestorovich, EM Nestorovich, F Yoshimura, FM Kaczmarek, G Schwarz, GA Jacoby, GE Schulz, H Nikaido, H Nikaido, H Nikaido, H Samartzidou, H Samartzidou, J Bredin, J Chevalier, J Chevalier, J-M Pagès, JC Cai, Jean-Marie Pagès, JM Bower, K Poole, L Kullman, L Martínez-Martínez, LB Rice, LJ Piddock, LP Randall, M Ceccarelli, M Guillier, M Luckey, M Malléa, M Olesky, M Olesky, M Viveiros, MA Kohanski, Mathias Winterhalter, MM Ochs, N El Amin, P Valentin-Hansen, R Dutzler, R Iyer, R Iyer, R Koebnik, RE Hancock, RN Charrel, S Biswas, S Blot, S Hernández-Allés, S Hernández-Allés, S Nekolla, S Vidal, S Vidal, SF Epp, SM Bezrukov, SM Bezrukov, SR Norrby, SW Cowan, T Ferenci, T Mach, UO Hasdemir, V Simonet, V Simonet, WL Veal, WM Shafer, WR Bauer, XZ Li   +95 more
core   +1 more source

Bacterial outer membrane constriction [PDF]

Molecular Microbiology, 2018
SummaryThe outer membrane of Gram‐negative bacteria is a crucial permeability barrier allowing the cells to survive a myriad of toxic compounds, including many antibiotics. This innate form of antibiotic resistance is compounded by the evolution of more active mechanisms of resistance such as efflux pumps, reducing the already limited number of ...
openaire   +3 more sources

Lipopolysaccharide Transport to the Bacterial Outer Membrane in Spheroplasts [PDF]

Journal of Biological Chemistry, 2005
The mechanism of lipopolysaccharide (LPS) transport in Gram-negative bacteria from the inner membrane to the outer membrane is largely unknown. Here, we investigated the possibility that LPS transport proceeds via a soluble intermediate associated with a periplasmic chaperone analogous to the Lol-dependent transport mechanism of lipoproteins.
Tefsen, B., Geurtsen, J., Beckers, F., Tommassen, J., Cock, H.   +4 more
openaire   +5 more sources

Solute channels of the outer membrane: from bacteria to chloroplasts [PDF]

, 2007
Chloroplasts, unique organelles of plants, originated from endosymbiosis of an ancestor of today's cyanobacteria with a mitochondria-containing host cell. It is assumed that the outer envelope membrane, which delimits the chloroplast from the surrounding
Aljamal J.A., Benz R., Blumenthal A., Drea S.C., Fischer K., Murcha M.W., Pilsl H., Umeda H., Zizi M.   +8 more
core   +1 more source

Biomimetic Nanoparticles Coated with Bacterial Outer Membrane Vesicles as a New-Generation Platform for Biomedical Applications

Pharmaceutics, 2021
The biomedical field is currently reaping the benefits of research on biomimetic nanoparticles (NPs), which are synthetic nanoparticles fabricated with natural cellular materials for nature-inspired biomedical applications.
Atanu Naskar, Hyejin Cho, Sohee Lee, Kwang-sun Kim   +3 more
semanticscholar   +1 more source

Exploring the biochemistry at the extracellular redox frontier of bacterial mineral Fe(III) respiration [PDF]

, 2012
Many species of the bacterial Shewanella genus are notable for their ability to respire in anoxic environments utilizing insoluble minerals of Fe(III) and Mn(IV) as extracellular electron acceptors.
Andrew J. Gates, Brutinel, Clarke, Coursolle, Coursolle, David J. Richardson, Donald, Fredrickson, Gadsby, Gaye F. White, Goodin, Hartshorne, Hartshorne, Jim Fredrickson, John Zachara, Julea N. Butt, Liang Shi, Marcus J. Edwards, McLean, Nanakow Baiden, Reardon, Robert S. Hartshorne, Ross, Shi, Shi, Shi, Thomas A. Clarke, Wang   +27 more
core   +3 more sources

Outer membrane permeabilization is an essential step in the killing of gram-negative bacteria by the lectin RegIIIβ. [PDF]

PLoS ONE, 2013
The C-type lectin RegIIIβ can kill certain Gram-positive and Gram-negative bacteria. The susceptibility of S. Typhimurium depends on the bacterial growth phase, i.e., bacteria from the logarithmic growth phase do bind RegIIIβ and are subsequently killed.
Tsuyoshi Miki, Wolf-Dietrich Hardt
doaj   +1 more source