Role of Outer Membrane Vesicles in Bacterial Physiology and Host Cell Interactions
Infectious Microbes & Diseases, 2020 . Outer membrane vesicles (OMVs) are spherical particles shed from the outer membrane of Gram-negative bacteria, which contain the typical components present in the outer membrane, although enrichment of specific molecules may occur, and furthermore a ...
Lingyu Gao +2 more
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A Bilayer-Couple Model of Bacterial Outer Membrane Vesicle Biogenesis
mBio, 2012 Gram-negative bacteria naturally produce outer membrane vesicles (OMVs) that arise through bulging and pinching off of the outer membrane. OMVs have several biological functions for bacteria, most notably as trafficking vehicles for toxins ...
Jeffrey W. Schertzer, Marvin Whiteley
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Subdominant antigens in bacterial vaccines: AM779 is subdominant in the Anaplasma marginale outer membrane vaccine but does not associate with protective immunity. [PDF]
PLoS ONE, 2012 Identification of specific antigens responsible for the ability of complex immunogens to induce protection is a major goal in development of bacterial vaccines.
Saleh M Albarrak +8 more
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The bacterial outer membrane is an evolving antibiotic barrier [PDF]
Proceedings of the National Academy of Sciences, 2018 The outer membrane (OM) of the diderm “gram-negative” class of bacteria is an essential organelle and a robust permeability barrier that prevents many antibiotics from reaching their intracellular targets (1). The OM is a unique asymmetrical lipid bilayer (Fig.
Kerrie L. May, Marcin Grabowicz
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Bacterial Outer Membrane Vesicles Induce Plant Immune Responses
Molecular Plant-Microbe Interactions, 2016 Gram-negative bacteria continuously pinch off portions of their outer membrane, releasing membrane vesicles. These outer membrane vesicles (OMVs) are involved in multiple processes including cell-to-cell communication, biofilm formation, stress tolerance,
Ofir Bahar +7 more
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Commensal bacterial outer membrane protein A induces interleukin-22 production. [PDF]
Cell RepSummary: Interleukin (IL)-22 promotes host-microbiota homeostasis. We sought to identify microbiota metabolite(s) that drive intestinal IL-22 production.
Wang Y, Ngo VL, Zou J, Gewirtz AT.
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Engineered Bacterial Outer Membrane Vesicles as Multifunctional Delivery Platforms
Frontiers in Materials, 2020 Outer membrane vesicles (OMVs) are valued for their unique, convenient, and amendable functions. They are flexible, controllable nanoparticles, which can be modified in different ways, for use in a wide array of applications like adjuvants, vaccines ...
Ruizhen Li, Qiong Liu, Qiong Liu
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The structure of bacterial outer membrane proteins
Biochimica et Biophysica Acta (BBA) - Biomembranes, 2002 Integral membrane proteins come in two types, alpha-helical and beta-barrel proteins. In both types, all hydrogen bonding donors and acceptors of the polypeptide backbone are completely compensated and buried while nonpolar side chains point to the membrane. The alpha-helical type is more abundant and occurs in cytoplasmic (or inner) membranes, whereas
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Surface Polysaccharide Extraction and Quantification
Bio-Protocol, 2013 Gram-negative bacterial cells possess two membranes - the inner cytoplasmic membrane and the outer membrane. The two membranes are distinct in their composition; the inner membrane is composed of a phospholipid bilayer, whereas the outer membrane (OM) is
Cedric Brimacombe, John Beatty
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Dual recognition of multiple signals in bacterial outer membrane proteins enhances assembly and maintains membrane integrity. [PDF]
ElifeOuter membrane proteins (OMPs) are essential components of the outer membrane of Gram-negative bacteria. In terms of protein targeting and assembly, the current dogma holds that a ‘β-signal’ imprinted in the final β-strand of the OMP engages the β-barrel
Germany EM +15 more
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