Bacterial outer membrane constriction [PDF]
SummaryThe outer membrane of Gram‐negative bacteria is a crucial permeability barrier allowing the cells to survive a myriad of toxic compounds, including many antibiotics. This innate form of antibiotic resistance is compounded by the evolution of more active mechanisms of resistance such as efflux pumps, reducing the already limited number of ...
openaire +3 more sources
Bacterial outer membrane vesicles as a candidate tumor vaccine platform
Cancer represents a serious concern for human life and health. Due to drug resistance and the easy metastasis of tumors, there is urgent need to develop new cancer treatment methods beyond the traditional radiotherapy, chemotherapy, and surgery ...
Shuming Wang +10 more
semanticscholar +1 more source
Solute channels of the outer membrane: from bacteria to chloroplasts [PDF]
Chloroplasts, unique organelles of plants, originated from endosymbiosis of an ancestor of today's cyanobacteria with a mitochondria-containing host cell. It is assumed that the outer envelope membrane, which delimits the chloroplast from the surrounding
Aljamal J.A. +8 more
core +1 more source
Exploring the biochemistry at the extracellular redox frontier of bacterial mineral Fe(III) respiration [PDF]
Many species of the bacterial Shewanella genus are notable for their ability to respire in anoxic environments utilizing insoluble minerals of Fe(III) and Mn(IV) as extracellular electron acceptors.
Andrew J. Gates +27 more
core +3 more sources
Outer membrane permeabilization is an essential step in the killing of gram-negative bacteria by the lectin RegIIIβ. [PDF]
The C-type lectin RegIIIβ can kill certain Gram-positive and Gram-negative bacteria. The susceptibility of S. Typhimurium depends on the bacterial growth phase, i.e., bacteria from the logarithmic growth phase do bind RegIIIβ and are subsequently killed.
Tsuyoshi Miki, Wolf-Dietrich Hardt
doaj +1 more source
Pathogen-host reorganization during Chlamydia invasion revealed by cryo-electron tomography [PDF]
Invasion of host cells is a key early event during bacterial infection, but the underlying pathogen-host interactions are yet to be fully visualised in three-dimensional detail.
Hackstadt T. +6 more
core +1 more source
HELICOBACTER PYLORI OIPA VIRULENCE GENE AS A MOLECULAR MARKER OF SEVERE GASTROPATHIES [PDF]
Background: Helicobacter pylori is an etiologic agent of gastroduodenal diseases. The microorganism, considered a type I carcinogen, affects about 50% of the global population. H.
Diogo Nery MACIEL +4 more
doaj +1 more source
Targeting bacterial outer-membrane remodelling to impact antimicrobial drug resistance.
The cell envelope is essential for survival and adaptation of bacteria. Bacterial membrane proteins include the major porins that mediate the influx of nutrients and several classes of antimicrobial drugs.
Natalia C Rosas, T. Lithgow
semanticscholar +1 more source
In vitro and in vivo screening for novel essential cell-envelope proteins in Pseudomonas aeruginosa [PDF]
The Gram-negative bacterium Pseudomonas aeruginosa represents a prototype of multi-drug resistant opportunistic pathogens for which novel therapeutic options are urgently required.
Bragonzi, Alessandra +5 more
core +1 more source
The cytochrome c import pathway differs markedly from the general route taken by the majority of other imported proteins, which is characterized by the import involvement of namely, surface receptors, the general insertion protein (GIP), contact sites ...
Berkout +68 more
core +1 more source

