Results 121 to 130 of about 1,583,285 (309)

Exploring the influence of lactoferrin on wound healing and related signaling pathways: a systematic review

FEBS Open Bio, EarlyView.
Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo, Kátia Cristiane Hall, Matheus dos Santos Fernandez, Geovanna Peter Corrêa, Rafael Guerra Lund   +4 more
wiley   +1 more source

Genomic signatures of human and animal disease in the zoonotic pathogen Streptococcus suis. [PDF]

, 2015
Streptococcus suis causes disease in pigs worldwide and is increasingly implicated in zoonotic disease in East and South-East Asia. To understand the genetic basis of disease in S.
Schultsz, C, Langford, P.R., Maglennon, Gareth A, Campbell, J., Wang, J., Chieu, T.T.B., Tran, TBC, Wren, B.W., Hoa, N.T., Tucker, Alexander W, Corander, Jukka, Corander, J., Ngo Thi, H, Schultsz, Constance, Valimaki, N, Wren, BW, Schultsz, C., Farrar, Jeremy, Holden, M T G, Wren, B W, Baker, S., Peters, Sarah E., Wang, Jinhong, Jombart, T., Maskell, DJ, Cuccui, Jon, Vehkala, Minna, Chaudhuri, RR, Chieu, TTB, Campbell, James, Rycroft, Andrew N, Campbell, J, Weinert, Lucy A, Wren, Brendan W, BRaDP1T Consortium, Chaudhuri, R R, Wang, J, Chaudhuri, Roy R, Terra, Vanessa, Chieu, Tran Thi Bich, Baig, Abiyad, Rycroft, A N, Nguyen, VVC, Howell, Kate J, Parkhill, Julian, Maskell, D J, Bentley, S D, Chaudhuri, R.R., Chau, N.V.V., Howell, Kate J., Baker, Stephen, Valimaki, N., Jombart, Thibaut, Baker, S, Ngo Thi Hoa, Tucker, AW, Weinert, LA, Ngo, TH, Baig, A., Peters, S.E., Rycroft, A.N., Tucker, A.W., Holden, Matthew T G, Tucker, Alexander W., Chau, Nguyen Van Vinh, Howell, K.J., Peters, SE, Vehkala, M, Parkhill, J, Matthews, Dominic, Vehkala, M., Peters, S E, Bentley, Stephen D, Harris, D., Langford, PR, Chaudhuri, Roy R., Bentley, Stephen D., Holden, Matthew T. G., Tran Thi Bich Chieu, Nguyen, Van Vinh Chau, Baig, A, Farrar, J, Corander, J, Li, Yanwen, Langford, Paul R, Holden, M.T.G., Weinert, Lucy A., Bosse, Janine T, Jombart, T, Välimäki, Niko, Bentley, S.D., Holden, MTG, Tran, Thi Bich Chieu, Maskell, Duncan J, Hoa, NT, Rycroft, Andrew N., Rycroft, AN, Tucker, A W, Maskell, Duncan J., Langford, Paul R., Bentley, SD, Peters, Sarah E, Holden, Matthew TG, Howell, K J, Farrar, J., Parkhill, J., Wren, Brendan W., Weinert, L.A., Nguyen Van Vinh Chau, Maskell, D.J., BRaDP1T Consortium,, Hoa, Ngo Thi, Van Vinh Chau, Nguyen, Weinert, L A, Howell, KJ, Nguyen Van Vinh, C, Harris, D, Langford, P R, Van Vinh Chau, N, Harris, David, Tran Thi Bich, C, Vaelimaeki, N   +121 more
core   +6 more sources

Novel induction of broad-spectrum antibiotics by the human pathogen Legionella

mSphere
The majority of antibiotics are natural products, with microorganism-generated molecules and their derivatives being the most prevalent source of drugs to treat infections.
Carson J. Shin, Tamara J. O'Connor
doaj   +1 more source

Isoprenoid biosynthesis in bacterial pathogens

Microbiology, 2012
Isoprenoid biosynthesis is essential for cell survival. Over 35 000 isoprenoid molecules have been identified to date in the three domains of life (bacteria, archaea and eukaryotes), and these molecules are involved in a wide variety of vital biological functions.
Sinéad, Heuston, Máire, Begley, Cormac G M, Gahan, Colin, Hill   +3 more
openaire   +2 more sources

Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model

FEBS Open Bio, EarlyView.
This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito, Haduki Asano, Ayano Ueki, Joe Sakamoto, Yasuhiro Kamei, Hayato Tokumoto, Ayaka Yazawa, Shigeki Kamitani   +7 more
wiley   +1 more source

Genomic investigations unmask Mycoplasma amphoriforme, a new respiratory pathogen [PDF]

, 2014
Funding: The Wellcome Trust [grants 098051 and 097831/Z/11/B (to J. M. B., S. R. H., H. M. B. S.-S., N. R. T.)], The Medical Research Council (grant number G1000413 [to J. M.
Oravcova, Katarina, McHugh, Timothy D., Bryant, Josephine M, Bébéar, Cecile, Ling, Clare L., Webster, David, Seth-Smith, Helena M B, Pinheiro, Miguel, Seth-Smith, Helena M., Wells, Louise, Gillespie, Stephen H., Harris, Simon R., Gillespie, Stephen H, Ling, Clare L, Thomson, Nicholas R, Thomson, Nicholas R., Bryant, Josephine M., Harris, Simon R, Seth-Smith, Helena M.B., McHugh, Timothy D   +19 more
core   +1 more source

Platelets interact with bacterial pathogens [PDF]

Thrombosis and Haemostasis, 2009
Thromb Haemost 2009; 102: 613–614 The predominant role of platelets is in haemostasis. Resting platelets patrol the vasculature and become activated in response to endothelial cell damage and exposure to subendothelial matrix components, such as collagen or von Willebrand factor. Adhesion and activation result in the release of the contents of platelet
openaire   +2 more sources

Identifying and characterising a plant GH1 β‐glucosidase that exhibits hydrolytic activity on N‐linked glucopyranoside

FEBS Open Bio, EarlyView.
We report the first β‐glucosidase with demonstrated hydrolytic activity on an N‐linked glycopyranoside. The enzyme, native to maize, was biochemically characterised for this novel reaction, and structural modelling of the enzyme–substrate complex revealed several clues to the underlying reduced catalytic rate relative to its native O‐glycopyranoside ...
Hani Gharabli, Carlotta Chiesa, Maher Abou Hachem, Ditte Hededam Welner   +3 more
wiley   +1 more source

CO(2) acts as a signalling molecule in populations of the fungal pathogen Candida albicans. [PDF]

, 2010
When colonising host-niches or non-animated medical devices, individual cells of the fungal pathogen Candida albicans expand into significant biomasses. Here we show that within such biomasses, fungal metabolically generated CO(2) acts as a communication
Topal Hüsnü, Maccallum, Donna M., Hall, Rebecca, Fritz A. Mühlschlegel, Gow, Neil A R, Hall, Rebecca A., Rebecca A Hall, Bloor, JW, Bloor James W., Neil A. R. Gow, Steegborn Clemens, James W, Bloor, James W., Muehlschlegel, Fritz A, Rebecca A. Hall, Buck, Jochen, Hall, RA, Wang Yue, Gow, Neil A. R., Hüsnü Topal, Hall Rebecca A., Buck Jochen, Fritz A Mühlschlegel, Eaton Rebecca, Wang, Yue, Donna M. Maccallum, Mühlschlegel Fritz A., MacCallum, Donna M, De Sordi, Luisa, Levin Lonny R., Gary K Robinson, Jochen Buck, Maccallum, DM, James W. Bloor, Steegborn, Clemens, Neil A R Gow, Topal, Husnu, Mühlschlegel, Fritz A, MacCallum Donna M., Eaton, R, De Sordi, L, Levin, LR, Gary K. Robinson, Steegborn, C, Rebecca Eaton, Luisa De Sordi, Mühlschlegel, FA, Clemens Steegborn, Robinson, GK, Lonny R Levin, Mühlschlegel, Fritz A., De Sordi Luisa, Wang, Y, Levin, Lonny R., Gow Neil A. R., Donna M Maccallum, Levin, Lonny R, Topal, Huesnue, Topal, H, Robinson, Gary K, Gow, NA, Lonny R. Levin, Eaton, Rebecca, James W Bloor, Hall, Rebecca; id_orcid, Bloor, James W, Robinson Gary K., Buck, J, Yue Wang, Robinson, Gary K.   +69 more
core   +1 more source

Three Xanthomonas Cell Wall Degrading Enzymes and Sorghum Brown midrib12 Contribute to Virulence and Resistance in the Bacterial Leaf Streak Pathosystem

Molecular Plant-Microbe Interactions
With an increasing demand for renewable fuels, bioenergy crops are being developed with high sugar content and altered cell walls to improve processing efficiency. These traits may have unintended consequences for plant disease resistance.
Qi Wang, Kira M. Veley, Joshua M. B. Johnson, Josh Sumner, Gijs van Erven, Mirjam A. Kabel, Singha Dhungana, Jeffrey Berry, Adam Boyher, David M. Braun, Wilfred Vermerris, Rebecca S. Bart   +11 more
doaj   +1 more source