Visualizing the invisible: novel approaches to visualizing bacterial proteins and host-pathogen interactions [PDF]
Frontiers in Bioengineering and BiotechnologyHost-pathogen interactions play a critical role in infectious diseases, and understanding the underlying mechanisms is vital for developing effective therapeutic strategies.
Moirangthem Kiran Singh +2 more
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Detection of Antimicrobial Proteins/Peptides and Bacterial Proteins Involved in Antimicrobial Resistance in Raw Cow’s Milk from Different Breeds [PDF]
AntibioticsProteins involved in antibiotic resistance (resistome) and with antimicrobial activity are present in biological specimens. This study aims to explore the presence and abundance of antimicrobial peptides (AMPs) and resistome proteins in bovine milk from ...
Cristian Piras +8 more
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Anticancer Activity of Bacterial Proteins and Peptides [PDF]
Pharmaceutics, 2018 Despite much progress in the diagnosis and treatment of cancer, tumour diseases constitute one of the main reasons of deaths worldwide. The side effects of chemotherapy and drug resistance of some cancer types belong to the significant current ...
Tomasz M. Karpiński, Artur Adamczak
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Acetylated bacterial proteins as potent antigens inducing an anti-modified protein antibody response [PDF]
RMD OpenObjective Gut-residing bacteria, such as Escherichia coli, can acetylate their proteome under conditions of amine starvation. It is postulated that the (gut) microbiome is involved in the breach of immune tolerance to modified self-proteins leading to ...
Tom W J Huizinga +9 more
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Synthesized Geopolymers Adsorb Bacterial Proteins, Toxins, and Cells [PDF]
Frontiers in Bioengineering and Biotechnology, 2020 Pore-forming and hemolytic toxins are bacterial cytotoxic proteins required for virulence in many pathogens, including staphylococci and streptococci, and are notably associated with clinical manifestations of disease.
John Popovich +10 more
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Exo-Tox: Identifying Exotoxins from secreted bacterial proteins [PDF]
BioData MiningBackground Bacterial exotoxins are secreted proteins able to affect target cells, and associated with diseases. Their accurate identification can enhance drug discovery and ensure the safety of bacteria-based medical applications.
Tanja Krueger +2 more
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Mapping functional regions of essential bacterial proteins with dominant-negative protein fragments. [PDF]
Proc Natl Acad Sci U S A, 2022 Savinov A, Fernandez A, Fields S.
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Chemistry Proceedings, 2022 The search for new antibacterial drugs has continued to be an urgent matter. One of the approaches is the development of covalent inhibitors using biochemoinformatics at the initial stages.
Polina Yakovets +3 more
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Animals, 2022 (1) Human milk (HM) is a source of many microorganisms, whose structure contains microbial protein (MP). In addition to the known health-promoting properties of HM, many activities, including immunoreactivity, may result from the presence of MP.
Anna Maria Ogrodowczyk +2 more
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The Role of Outer Membrane Proteins in UPEC Antimicrobial Resistance: A Systematic Review
Membranes, 2022 Uropathogenic Escherichia coli (UPEC) are one of the most common agents of urinary tract infection. In the last decade, several UPEC strains have acquired antibiotic resistance mechanisms and some have become resistant to all classes of antibiotics. UPEC
Inês C. Rodrigues +4 more
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