Results 41 to 50 of about 1,338,778 (300)

Adaptive response and enlargement of dynamic range [PDF]

, 2011
Many membrane channels and receptors exhibit adaptive, or desensitized, response to a strong sustained input stimulus, often supported by protein activity-dependent inactivation.
A. Csik\'asz-Nagy, A. Lupas, B. A. Mello, B. N. Kholodenko, B. Wark, C. H. Hansen, E. N. Pugh Jr., G. L. Hazelbauer, J. E. Keymer, J. J. Tyson, K. Ogata, M. Behar, M. J. Tindall, M. N. Levit, N. Barkai, P. Dunten, P. Francois, R. A. Normann, R. B. Bourret, S. A. Simms, S. Asakura, S. Marom, T. C. Terwilliger, T. M. Yi, T.Friedlander, V. Sourjik, W. Ma, Y. Tu   +27 more
core   +1 more source

Detection of the babA2 adhesin gene in Helicobacter pylori clinical isolates and correlation with upper gastrointestinal diseases [PDF]

Anais da Academia Brasileira de Ciências
Helicobacter pylori is an oncobacteria that infects more than half of the world’s population. Adhesins are virulence factors that are essential for the microorganism to bind to the gastric mucosa, such as the BabA adhesion protein, which is associated ...
DIOGO NERY MACIEL, SILVANA B. SANTIAGO, VIVIANE L. ROCHA, GABRIELA L. DOS SANTOS, LUCAS T. RASMUSSEN, MÔNICA S. BARBOSA   +5 more
doaj   +1 more source

Socializing, networking and development: a report from the second ‘Young Microbiologists Symposium on Microbe Signalling, Organization and Pathogenesis’ [PDF]

, 2012
In mid-June, the second Young Microbiologists Symposium took place under the broad title of ‘Microbe signalling, organization and pathogenesis’ on the picturesque campus of University College Cork, Ireland.
Barret, Brackman, Brown, Bush, Cascales, Corrigan, Costerton, Coulthurst, D'Autreaux, Davey, Delalez, Fazli, Gerlach, Hagan, Holland, Hood, Housden, Kleanthous, Kuchma, Kuchma, Kuchma, Lawley, Lebeer, Malone, McCarthy, Merritt, Murdoch, O'Connell Motherway, O'Connell Motherway, O'Toole, Porter, Ramsay, Ramsay, Rigel, Roberts, Ryan, Ryan, Ryan, Ryan, Ryan, Schwarz, Sharma, Shioya, Smith, Thompson, Twomey, Waters, Yang, Youle   +48 more
core   +1 more source

Bacterial protein interaction networks: connectivity is ruled by gene conservation, essentiality and function [PDF]

, 2020
Protein-protein interaction (PPI) networks are the backbone of all processes in living cells. In this work we relate conservation, essentiality and functional repertoire of a gene to the connectivity $k$ of the corresponding protein in the PPI networks ...
Cimini, Giulio, Dilucca, Maddalena, Giansanti, Andrea   +2 more
core   +2 more sources

A saposin-lipoprotein nanoparticle system for membrane proteins. [PDF]

, 2016
A limiting factor in membrane protein research is the ability to solubilize and stabilize such proteins. Detergents are used most often for solubilizing membrane proteins, but they are associated with protein instability and poor compatibility with ...
Armache, Jean-Paul, Briggs, John AG, Cheng, Yifan, Flayhan, Ali, Frauenfeld, Jens, Garoff, Henrik, Guettou, Fatma, Jegerschöld, Caroline, Löving, Robin, Löw, Christian, Moberg, Per, Nordlund, Pär, Sonnen, Andreas F-P, Zhu, Lin   +13 more
core   +2 more sources

Structural Characterization of Mycobacterium tuberculosis Encapsulin in Complex with Dye-Decolorizing Peroxide

Microorganisms
Mycobacterium tuberculosis (Mtb) is the causative agent of tuberculosis, the world’s deadliest infectious disease. Mtb uses a variety of mechanisms to evade the human host’s defenses and survive intracellularly.
Bonnie J. Cuthbert, Xiaorui Chen, Kalistyn Burley, Gaëlle Batot, Heidi Contreras, Shandee Dixon, Celia W. Goulding   +6 more
doaj   +1 more source

Evolutionary behaviour of bacterial prion-like proteins.

PLoS ONE, 2019
Prions in eukaryotes have been linked to diseases, evolutionary capacitance, large-scale genetic control and long-term memory formation. In bacteria, constructed prion-forming proteins have been described, such as the prion-forming protein recently ...
Paul M Harrison
doaj   +1 more source

Proteomic Approach for Extracting Cytoplasmic Proteins from Streptococcus sanguinis using Mass Spectrometry [PDF]

, 2017
Streptococcus sanguinis is a commensal and early colonizer of oral cavity as well as an opportunistic pathogen of infectious endocarditis. Extracting the soluble proteome of this bacterium provides deep insights about the physiological dynamic changes ...
Elrami, Fadi, Nelson, Kristina, Xu, Ping
core   +3 more sources

Quantitative Proteomic Analysis Reveals Changes in the Benchmark Corynebacterium pseudotuberculosis Biovar Equi Exoproteome after Passage in a Murine Host [PDF]

, 2017
Corynebacterium pseudotuberculosis biovar equi is the etiologic agent of ulcerative lymphangitis. To investigate proteins that could be related to the virulence of this pathogen, we combined an experimental passage process using a murine model and high ...
Adriano M. C. Pimenta, Artur Silva, Edson L. Folador, Fernanda A. Dorella, Gustavo H. M. F. Souza, Henrique C. P. Figueiredo, Rodrigo D. De Oliveira Carvalho, Vasco Azevedo, Wanderson M. Silva, Wanderson M. Silva, Wanderson M. Silva, Yves Le Loir, Yves Le Loir   +12 more
core   +4 more sources

Bacterial Signal Peptides- Navigating the Journey of Proteins

Frontiers in Physiology, 2022
In 1971, Blobel proposed the first statement of the Signal Hypothesis which suggested that proteins have amino-terminal sequences that dictate their export and localization in the cell.
Sharbani Kaushik, Haoze He, Ross E. Dalbey   +2 more
doaj   +1 more source