Results 41 to 50 of about 3,299,929 (298)

Translocation of bacterial proteins?an overview

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 2004
Recent progress in the understanding of the nature of the extraordinary variety of protein translocation systems, mainly in Gram negative bacteria, is reviewed. This takes us from the insertion of proteins into the inner membrane via the sophisticated Sec apparatus, the lethal injection of Type III proteins into host cells and on to the beautiful ...
openaire   +2 more sources

The protein network of bacterial motility

Molecular Systems Biology, 2007
Motility is achieved in most bacterial species by the flagellar apparatus. It consists of dozens of different proteins with thousands of individual subunits. The published literature about bacterial chemotaxis and flagella documented 51 protein-protein interactions (PPIs) so far. We have screened whole genome two-hybrid arrays of Treponema pallidum and
Rajagopala, Seesandra V, Titz, Bjorn, Goll, Johannes, Parrish, Jodi R, Wohlbold, Katrin, McKevitt, Matthew T, Palzkill, Timothy, Mori, Hirotada, Finley, Russell L, Uetz, Peter   +9 more
openaire   +4 more sources

Abatacept for Prophylaxis of Acute and Chronic Graft‐Versus‐Host‐Disease in Children Undergoing Allogeneic Hematopoietic Stem Cell Transplantation—A Systematic Review and Meta‐Analysis of Cohort Studies

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Graft‐versus‐host disease (GvHD) remains one of the most significant complications of hematopoietic stem cell transplantation (HSCT). Abatacept, a selective T‐cell costimulation modulator, is a relatively novel prophylactic agent, though pediatric data remain limited.
Matthijs D. Kruizinga, Anne B. Verbeek, Caroline A. Lindemans, Emilie P. Buddingh   +3 more
wiley   +1 more source

Structural Characterization of Mycobacterium tuberculosis Encapsulin in Complex with Dye-Decolorizing Peroxide

Microorganisms
Mycobacterium tuberculosis (Mtb) is the causative agent of tuberculosis, the world’s deadliest infectious disease. Mtb uses a variety of mechanisms to evade the human host’s defenses and survive intracellularly.
Bonnie J. Cuthbert, Xiaorui Chen, Kalistyn Burley, Gaëlle Batot, Heidi Contreras, Shandee Dixon, Celia W. Goulding   +6 more
doaj   +1 more source

ANAPHYLAXIS INDUCED BY BACTERIAL PROTEINS. [PDF]

Journal of the American Medical Association, 1908
The discovery of the production of hypersensibility, in animals to horse serum, egg white, etc., suggested the possibility of a similar hypersensitization to other proteid materials. It was thought possible that the protoplasm of bacterial cells might lead to similar effects, and in consequence there might be danger from the employment of bacterial ...
openaire   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Surface Inactivation of Bacterial Viruses and of Proteins

Substantia, 2023
The extraordinary paper of Mark H. Adams:  Surface Inactivation of Bacterial Viruses and of Proteins appeared in a mainstream Journal of Physiology, in 1948. It was neglected and has been ever since.
Mark H. Adams, Barry W. Ninham
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Synthesis of empty bacterial microcompartments, directed organelle protein incorporation, and evidence of filament-associated organelle movement [PDF]

, 2010
Compartmentalization is an important process, since it allows the segregation of metabolic activities and, in the era of synthetic biology, represents an important tool by which defined microenvironments can be created for specific metabolic functions ...
Prentice, M.B., Mulvihill, D.P., Frank, S., Bhella, D., Frank, Stefanie, Parsons, J.B., Bhella, David, Prentice, Michael B., Liang, M., Mulvihill, Daniel P., Warren, Martin J., Parsons, Joshua B., Warren, M.J., Liang, Mingzhi   +13 more
core   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source