Results 51 to 60 of about 1,338,778 (300)

Deficiency of RgpG causes major defects in cell division and biofilm formation, and deficiency of LytR-CpsAPsr family proteins leads to accumulation of cell wall antigens in culture medium by Streptococcus mutans [PDF]

, 2017
Streptococcus mutans is known to possess rhamnose-glucose polysaccharide (RGP), a major cell wall antigen. S. mutans strains deficient in rgpG , encoding the first enzyme of the RGP biosynthesis
Beatty, Wandy L, Bitoun, Jacob P, De, Arpan, Liao, Sumei, Roth, Randy, Wen, Zezhang T, Wu, Hui   +6 more
core   +2 more sources

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Advancements in Immunology and Microbiology Research: A Comprehensive Exploration of Key Areas

Microorganisms
Immunology and microbiology research has witnessed remarkable growth and innovation globally, playing a pivotal role in advancing our understanding of immune mechanisms, disease pathogenesis, and therapeutic interventions.
Angel Justiz-Vaillant, Darren Gopaul, Sachin Soodeen, Chandrashekhar Unakal, Reinand Thompson, Shalini Pooransingh, Rodolfo Arozarena-Fundora, Odalis Asin-Milan, Patrick Eberechi Akpaka   +8 more
doaj   +1 more source

STAS Domain Only Proteins in Bacterial Gene Regulation

Frontiers in Cellular and Infection Microbiology, 2021
Sulfate Transport Anti-Sigma antagonist domains (Pfam01740) are found in all branches of life, from eubacteria to mammals, as a conserved fold encoded by highly divergent amino acid sequences.
Brian E. Moy, J. Seshu
doaj   +1 more source

The Multifaceted Activity of the VirF Regulatory Protein in the Shigella Lifestyle [PDF]

, 2016
Shigella is a highly adapted human pathogen, mainly found in the developing world and causing a severe enteric syndrome. The highly sophisticated infectious strategy of Shigella banks on the capacity to invade the intestinal epithelial barrier and cause ...
Colonna, Bianca, DI MARTINO, MARIA LETIZIA, Falconi, Maurizio, Micheli, Gioacchino, Prosseda, Gianni   +4 more
core   +3 more sources

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Surface Inactivation of Bacterial Viruses and of Proteins

Substantia, 2023
The extraordinary paper of Mark H. Adams:  Surface Inactivation of Bacterial Viruses and of Proteins appeared in a mainstream Journal of Physiology, in 1948. It was neglected and has been ever since.
Mark H. Adams, Barry W. Ninham
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Antimicrobial Activity and Mechanisms of Punicalagin against Vibrio parahaemolyticus

Foods
This study sought to explore the antimicrobial activity of punicalagin against V. parahaemolyticus and its potential modes of action. V. parahaemolyticus ATCC 17802 and RIMD 2210633Sm were exposed to punicalagin, and the energy production, membrane ...
Hongli Liu, Wenxiu Zhu, Yue Zou, Xiaodong Xia   +3 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source