Results 71 to 80 of about 3,299,929 (298)
, 2023 FASTA file of bacterial proteins present in the refined Global database. Used to analyze the results of the Global database searches.
Elliot Lee (12908801)
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Structural analysis of the protein shell of the propanediol utilisation metabolosome [PDF]
, 2012 PhDPropanediol metabolism occurs within a proteinaceous organelle in several bacterial species including Citrobacter freundii and Lactobacillus reuteri.
Pang, Allan
core +2 more sources
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Translocation of DNA across bacterial membranes [PDF]
, 1994 Dreiseikelmann B. Translocation of DNA across bacterial membranes. Microbiological Reviews.
Dreiseikelmann, Brigitte
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Modulation of host microtubule dynamics by pathogenic bacteria
Biomolecular Concepts, 2012 The eukaryotic cytoskeleton is a vulnerable target of many microbial pathogens during the course of infection. Rearrangements of host cytoskeleton benefit microbes in various stages of their infection cycle such as invasion, motility, and persistence ...
Radhakrishnan Girish K. +1 more
doaj +1 more source
Arginine glycosylation enhances methylglyoxal detoxification
Scientific Reports, 2021 Type III secretion system effector proteins have primarily been characterized for their interactions with host cell proteins and their ability to disrupt host signaling pathways.
Samir El Qaidi +2 more
doaj +1 more source
The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
Amplifying the innate immune response : cell-cell propagation of proinflammatory signals during bacterial infection [PDF]
, 2012 The enteroinvasive bacterium Shigella flexneri uses multiple secreted effector proteins to downregulate interleukin-8 (IL-8) expression in infected epithelial cells. Nevertheless, massive IL-8 secretion is observed in shigellosis. In this thesis, a novel
Kasper, Christoph Alexander
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