Results 71 to 80 of about 3,151,988 (194)

Exploitation of host polyubiquitination machinery through molecular mimicry by eukaryotic-like bacterial F-box effectors

open access: yesFrontiers in Cellular and Infection Microbiology, 2010
Microbial pathogens have evolved exquisite mechanisms to interfere and intercept host biological processes, often through molecular mimicry of specific host proteins.
Yousef eAbu Kwaik, Christopher T. Price
doaj   +1 more source

Comparison of bacterial intracellular and secreted proteins produced in milk versus medium for Escherichia coli by proteomic analysis

open access: yesJournal of Dairy Science
: The growth and reproduction of microorganisms are dependent on nutrient supply. Here, milk and Luria-Bertani (LB) media were used as nutrition sources for Escherichia coli, and the changes in bacterial and secretory proteins at 3 time points (3, 9, and
Qiyue Sun   +7 more
doaj   +1 more source

Bacterial flagellar capping proteins adopt diverse oligomeric states

open access: yeseLife, 2016
Flagella are crucial for bacterial motility and pathogenesis. The flagellar capping protein (FliD) regulates filament assembly by chaperoning and sorting flagellin (FliC) proteins after they traverse the hollow filament and exit the growing flagellum tip.
Sandra Postel   +12 more
doaj   +1 more source

Bacterial TIR domain-containing proteins as drug targets

open access: yes
As an alternative to traditional antibiotics that kill bacteria, we can interfere with bacterial virulence. Bacteria have many proteins that contain the so-called TIR (Toll/interleukin-1 receptor) domains, which are also found widely in animals and ...
Singh, M   +5 more
core   +1 more source

Bacterial Drug Efflux Proteins.

open access: yesNippon Saikingaku Zasshi, 1995
近年,数多くの薬剤排出系が様々な菌種に見いだされ,有力な化学療法剤耐性機構として認識されつつある。特に,臨床上問題視されているMRSAや緑膿菌などの多剤耐性菌に薬剤排出蛋白が多く存在することは注目すべきである。遺伝子解析により多くの排出蛋白のアミノ酸配列が明らかにされた。薬剤排出蛋白はいずれも細胞質膜に存在するが,薬剤排出のエネルギー源として,H+の電気化学的勾配を用いるものと,ATPを用いるものと2種類ある。また,構造上関連性のない多種の薬剤を認識し排出する多剤排出蛋白の存在が排出による薬剤耐性のひとつの特徴であるが,特異性の高い排出蛋白との間で一次配列の相同性が高く,多剤排出蛋白がどのように基質を認識しているのか興味が持たれる ...
SOMEYA, Yuichi, YAMAGUCHI, Akihito
openaire   +3 more sources

Bacterial AsmA Proteins Transfer Glycerophospholipids Between Membranes

open access: yesContact
Gram-negative bacteria are surrounded by inner and outer membranes whose glycerophospholipid building blocks are synthesized in the inner membrane and redistributed to the outer membrane by poorly understood mechanisms.
Matthew A. Schilling, Karin M. Reinisch
doaj   +1 more source

Domain organization of long autotransporter signal sequences [PDF]

open access: yes, 2010
Bacterial autotransporters represent a diverse family of proteins that autonomously translocate across the inner membrane of Gram-negative bacteria via the Sec complex and across the outer bacterial membrane.
Hiß, Jan Alexander   +1 more
core  

Hijacking Complement Regulatory Proteins for Bacterial Immune Evasion

open access: yesFrontiers in Microbiology, 2016
The human complement system plays an important role in the defense against invading pathogens, inflammation and homeostasis. Invading microbes, such as bacteria, directly activate the complement system resulting in the formation of chemoattractants and ...
Elise Sofie Hovingh   +4 more
doaj   +1 more source

Automatic selection of representative proteins for bacterial phylogeny

open access: yesBMC Evolutionary Biology, 2005
Background Although there are now about 200 complete bacterial genomes in GenBank, deep bacterial phylogeny remains a difficult problem, due to confounding horizontal gene transfers and other phylogenetic "noise".
Goldberg David, Bern Marshall
doaj   +1 more source

Synthesis of empty bacterial microcompartments, directed organelle protein incorporation, and evidence of filament-associated organelle movement [PDF]

open access: yes, 2010
Compartmentalization is an important process, since it allows the segregation of metabolic activities and, in the era of synthetic biology, represents an important tool by which defined microenvironments can be created for specific metabolic functions ...
Prentice, M.B.   +13 more
core   +1 more source

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