Results 81 to 90 of about 3,299,929 (298)

Understanding the Molecular Interactions Between Influenza A Virus and Streptococcus Proteins in Co-Infection: A Scoping Review

Pathogens
Influenza A virus infections are known to predispose infected individuals to bacterial infections of the respiratory tract that result in co-infection with severe disease outcomes.
Askar K. Alshammari, Meshach Maina, Adam M. Blanchard, Janet M. Daly, Stephen P. Dunham   +4 more
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Binding affinities of ligands and bacterial proteins.

, 2023
Binding affinities of ligands and bacterial proteins.
Aneela Javed (823897), Saiqa Andleeb (11442771), Sana Sabahat (16560975), Hafsah Mureed (16792748), Fahed Parvaiz (16792745), Sohaib Ahmad (9427314), Sadaf Azad Raja (6301382), Falak Naz (16792751)   +7 more
core   +1 more source

Potentially virulence-related extracellular proteins of Streptococcus equi [PDF]

, 2006
Equine strangles, a disease of the upper respiratory tract caused by the bacterium Streptococcus equi subspecies equi, is one of the most commonly diagnosed and serious diseases in horses. However, the molecular basis of S. equi subsp.
Lannergård, Jonas
core   +1 more source

Genetic Reporter System for Positioning of Proteins at the Bacterial Pole

mBio, 2012
Spatial organization within bacteria is fundamental to many cellular processes, although the basic mechanisms underlying localization of proteins to specific sites within bacteria are poorly understood.
Kathryn R. Fixen, Anuradha Janakiraman, Sean Garrity, Daniel J. Slade, Andrew N. Gray, Nilay Karahan, Ann Hochschild, Marcia B. Goldberg   +7 more
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

A combined approach for comparative exoproteome analysis of Corynebacterium pseudotuberculosis [PDF]

, 2011
Background: Bacterial exported proteins represent key components of the host-pathogen interplay. Hence, we sought to implement a combined approach for characterizing the entire exoproteome of the pathogenic bacterium Corynebacterium pseudotuberculosis,
Pimenta, Adriano M. C., Farias, Luiz M., Pacheco, Luis Gc, Sérgio C Oliveira, Castro, Thiago Lp, Scrivens, James, Agenor V Santos, Silva Wanderson M, Luiz M Farias, Maria AR Carvalho, Santos Anderson R, Slade Susan E, Anderson R Santos, Silva, Artur, Oliveira Sérgio C, Carvalho Maria AR, Wanderson M Silva, Silva, Wanderson M., Seyffert, Nbia, Azevedo, Vasco, Farias Luiz M, Thiago LP Castro, Dowson, Christopher G., Silva Artur, Slade, Susan E., Castro, Thiago L. P., Luis GC Pacheco, Pacheco, Luis G. C., Azevedo Vasco, James H Scrivens, Adriano MC Pimenta, Pimenta Adriano MC, Roberto Meyer, Seyffert, Núbia, Scrivens, James H., Carvalho, Maria A. R., Miyoshi Anderson, Núbia Seyffert, Santos Agenor V, Castro Thiago LP, Vasco Azevedo, Seyffert Núbia, Dowson Christopher G, Santos Simone G, Miyoshi, Anderson, Santos, Agenor V., Meyer, Roberto, Susan E Slade, Anderson Miyoshi, Simone G Santos, Santos, Simone G., Santos, Anderson R., Pacheco Luis GC, Carvalho, Maria Ar, Christopher G Dowson, Pimenta, Adriano Mc, Oliveira, Sérgio C., Meyer Roberto, Artur Silva, Scrivens James H   +59 more
core   +1 more source

Comparative NanoUPLC-MSE analysis between magainin I-susceptible and -resistant Escherichia coli strains

Scientific Reports, 2017
In recent years the antimicrobial peptides (AMPs) have been prospected and designed as new alternatives to conventional antibiotics. Indeed, AMPs have presented great potential toward pathogenic bacterial strains by means of complex mechanisms of action.
Marlon H. Cardoso, Keyla C. de Almeida, Elizabete de S. Cândido, André M. Murad, Simoni C. Dias, Octávio L. Franco   +5 more
doaj   +1 more source

Bacterial Drug Efflux Proteins.

Nippon Saikingaku Zasshi, 1995
近年,数多くの薬剤排出系が様々な菌種に見いだされ,有力な化学療法剤耐性機構として認識されつつある。特に,臨床上問題視されているMRSAや緑膿菌などの多剤耐性菌に薬剤排出蛋白が多く存在することは注目すべきである。遺伝子解析により多くの排出蛋白のアミノ酸配列が明らかにされた。薬剤排出蛋白はいずれも細胞質膜に存在するが,薬剤排出のエネルギー源として,H+の電気化学的勾配を用いるものと,ATPを用いるものと2種類ある。また,構造上関連性のない多種の薬剤を認識し排出する多剤排出蛋白の存在が排出による薬剤耐性のひとつの特徴であるが,特異性の高い排出蛋白との間で一次配列の相同性が高く,多剤排出蛋白がどのように基質を認識しているのか興味が持たれる ...
SOMEYA, Yuichi, YAMAGUCHI, Akihito
openaire   +3 more sources

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source