Results 11 to 20 of about 7,915,148 (365)
Bacterial copper storage proteins [PDF]
Journal of Biological Chemistry, 2018 Copper is essential for most organisms as a cofactor for key enzymes involved in fundamental processes such as respiration and photosynthesis. However, copper also has toxic effects in cells, which is why eukaryotes and prokaryotes have evolved mechanisms for safe copper handling.
Christopher, Dennison +2 more
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Deep mutational scanning of essential bacterial proteins can guide antibiotic development. [PDF]
Nat Commun, 2023 Deep mutational scanning can be used to investigate protein function and stability. Here, Dewachter et al. use deep mutational scanning on three essential bacterial proteins to study the mutations’ effects in their original genomic context, providing ...
Dewachter L +10 more
europepmc +2 more sources
Arming the troops: Post-translational modification of extracellular bacterial proteins. [PDF]
Sci Prog, 2020 Protein secretion is almost universally employed by bacteria. Some proteins are retained on the cell surface, whereas others are released into the extracellular milieu, often playing a key role in virulence.
Forrest S, Welch M.
europepmc +2 more sources
Enzymatic Labeling of Bacterial Proteins for Super-resolution Imaging in Live Cells. [PDF]
ACS Cent Sci, 2019 Methods that enable the super-resolution imaging of intracellular proteins in live bacterial cells provide powerful tools for the study of prokaryotic cell biology.
Ho SH, Tirrell DA.
europepmc +2 more sources
Kinetics of trifurcated electron flow in the decaheme bacterial proteins MtrC and MtrF. [PDF]
Proc Natl Acad Sci U S A, 2019 Significance Certain bacteria survive in anoxic environments by switching from aerobic to anaerobic respiration: in place of O2, they reduce diverse substrates outside the cell.
Jiang X +6 more
europepmc +2 more sources
Functional and structural characteristics of bacterial proteins that bind host cytokines. [PDF]
Virulence, 2017 Several human pathogens bind and respond to host cytokines, which can be considered a virulence mechanism that communicates defensive actions of the host to the pathogen. This review summarizes the current knowledge of bacterial cytokine-binding proteins,
Högbom M, Ihalin R.
europepmc +2 more sources
Animals, 2022 (1) Human milk (HM) is a source of many microorganisms, whose structure contains microbial protein (MP). In addition to the known health-promoting properties of HM, many activities, including immunoreactivity, may result from the presence of MP.
Anna Maria Ogrodowczyk +2 more
doaj +1 more source
The EXIT Strategy: an Approach for Identifying Bacterial Proteins Exported during Host Infection. [PDF]
mBio, 2017 Exported proteins of bacterial pathogens function both in essential physiological processes and in virulence. Past efforts to identify exported proteins were limited by the use of bacteria growing under laboratory (in vitro) conditions.
Perkowski EF +8 more
europepmc +2 more sources
The Role of Outer Membrane Proteins in UPEC Antimicrobial Resistance: A Systematic Review
Membranes, 2022 Uropathogenic Escherichia coli (UPEC) are one of the most common agents of urinary tract infection. In the last decade, several UPEC strains have acquired antibiotic resistance mechanisms and some have become resistant to all classes of antibiotics. UPEC
Inês C. Rodrigues +4 more
doaj +1 more source