Bacterial Approaches for Assembling Iron-Sulfur Proteins
mBio, 2021 Building iron-sulfur (Fe-S) clusters and assembling Fe-S proteins are essential actions for life on Earth. The three processes that sustain life, photosynthesis, nitrogen fixation, and respiration, require Fe-S proteins.
Karla Esquilin-Lebron +3 more
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Membraneless organelles formed by liquid-liquid phase separation increase bacterial fitness [PDF]
Sci Adv. 2021 Oct 22;7(43):eabh2929, 2021 Liquid-liquid phase separation is emerging as a crucial phenomenon in several fundamental cell processes. A range of eukaryotic systems exhibit liquid condensates. However, their function in bacteria, which in general lack membrane-bound compartments, remains less clear.
arxiv +1 more source
Journal of Functional Biomaterials, 2022 Bacterial polymeric silk is produced by Bacillus sp. strain NE and is composed of two proteins, called fibroin and sericin, with several biomedical and biotechnological applications.
Esmail M. El-Fakharany +6 more
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Friends in need: how chaperonins recognize and remodel proteins that require folding assistance [PDF]
Front. Mol. Biosci. (2022) 9:1071168, 2022 Chaperonins are biological nanomachines that help newly translated proteins to fold by rescuing them from kinetically trapped misfolded states. Protein folding assistance by the chaperonin machinery is obligatory in vivo for a subset of proteins in the bacterial proteome.
arxiv +1 more source
Impact of self-association on the architectural properties of bacterial nucleoid proteins [PDF]
Biophysical Journal, 120 (2021) 370-378, 2021 The chromosomal DNA of bacteria is folded into a compact body called the nucleoid, which is composed essentially of DNA (80%), RNA (10%), and a number of different proteins (10%). These nucleoid proteins act as regulators of gene expression and influence the organization of the nucleoid by bridging, bending, or wrapping the DNA.
arxiv +1 more source
Bacterial Enhancer Binding Proteins—AAA+ Proteins in Transcription Activation
Biomolecules, 2020 Bacterial enhancer-binding proteins (bEBPs) are specialised transcriptional activators. bEBPs are hexameric AAA+ ATPases and use ATPase activities to remodel RNA polymerase (RNAP) complexes that contain the major variant sigma factor, σ54 to convert
Forson Gao +5 more
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Exploring the mechanisms by which camel lactoferrin can kill Salmonella enterica serovar typhimurium and Shigella sonnei [PDF]
PeerJ, 2023 There is a continuously increasing pressure associated with the appearance of Salmonella enterica Serovar typhimurium (S. typhimurium) and Shigella sonnei (S.
Hussein A. Almehdar +7 more
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Frontiers in Microbiology, 2022 FtsZ is the cytoskeletal protein that organizes the formation of the septal ring and orchestrates bacterial cell division. Its association to the membrane is essential for its function.
Marisela Vélez
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Dissecting the Specificity of Protein-Protein Interaction in Bacterial Two-Component Signaling: Orphans and Crosstalks [PDF]
PLoS ONE 6(5): e19729 (2011), 2011 Predictive understanding of the myriads of signal transduction pathways in a cell is an outstanding challenge of systems biology. Such pathways are primarily mediated by specific but transient protein-protein interactions, which are difficult to study experimentally.
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HELICOBACTER PYLORI OIPA VIRULENCE GENE AS A MOLECULAR MARKER OF SEVERE GASTROPATHIES [PDF]
Arquivos de GastroenterologiaBackground: Helicobacter pylori is an etiologic agent of gastroduodenal diseases. The microorganism, considered a type I carcinogen, affects about 50% of the global population. H.
Diogo Nery MACIEL +4 more
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