Results 21 to 30 of about 757,127 (284)
Identification of direct residue contacts in protein-protein interaction by message passing [PDF]
Proc. Natl. Acad. Sci. 106(1), 67-72 (2009), 2009 Understanding the molecular determinants of specificity in protein-protein interaction is an outstanding challenge of postgenome biology. The availability of large protein databases generated from sequences of hundreds of bacterial genomes enables various statistical approaches to this problem. In this context covariance-based methods have been used to
arxiv +1 more source
ENGINEERED FLUORESCENT PROTEINS ILLUMINATE THE BACTERIAL PERIPLASM
Computational and Structural Biotechnology Journal, 2012 The bacterial periplasm is of special interest whenever cell factories are designed and engineered. Recombinantely produced proteins are targeted to the periplasmic space of Gram negative bacteria to take advantage of the authentic N-termini, disulfide ...
Thorben Dammeyer, Philip Tinnefeld
doaj +3 more sources
Alterations of the mitochondrial proteome caused by the absence of mitochondrial DNA: A proteomic view [PDF]
Electrophoresis 27 (04/2006) 1574-83, 2006 The proper functioning of mitochondria requires that both the mitochondrial and the nuclear genome are functional. To investigate the importance of the mitochondrial genome, which encodes only 13 subunits of the respiratory complexes, the mitochondrial rRNAs and a few tRNAs, we performed a comparative study on the 143B cell line and on its Rho-0 ...
arxiv +1 more source
Mobility of bacterial protein Hfq on dsDNA; Role of C-terminus mediated transient binding [PDF]
arXiv, 2021 The mobility of protein is fundamental in the machinery of life. Here, we have investigated the effect of DNA binding in conjunction with DNA internal motion of the bacterial Hfq master regulator devoid of its amyloid C-terminus domain. Hfq is one of the most abundant nucleoid associated proteins that shape the bacterial chromosome and is involved in ...
arxiv
Dynamic compartmentalization of bacteria: accurate division in E. coli [PDF]
Physical Review Letters, v87, p278102 (2001)., 2001 Positioning of the midcell division plane within the bacterium E. coli is controlled by the min system of proteins: MinC, MinD and MinE. These proteins coherently oscillate from end to end of the bacterium. We present a reaction--diffusion model describing the diffusion of min proteins along the bacterium and their transfer between the cytoplasmic ...
arxiv +1 more source
Bacterial Ice Crystal Controlling Proteins
Scientifica, 2014 Across the world, many ice active bacteria utilize ice crystal controlling proteins for aid in freezing tolerance at subzero temperatures. Ice crystal controlling proteins include both antifreeze and ice nucleation proteins.
Janet S. H. Lorv +2 more
doaj +1 more source
Bacterial protein interaction networks: connectivity is ruled by gene conservation, essentiality and function [PDF]
Current Genomics 22: 1 (2021), 2017 Protein-protein interaction (PPI) networks are the backbone of all processes in living cells. In this work we relate conservation, essentiality and functional repertoire of a gene to the connectivity $k$ (i.e., the number of interaction links) of the corresponding protein in the PPI network. On a set of 42 bacterial genomes of different sizes, and with
arxiv +1 more source
Entropic elasticity and dynamics of the bacterial chromosome: a simulation study [PDF]
, 2017 We study the compression and extension dynamics of a DNA-like polymer interacting with non-DNA binding and DNA-binding proteins, by means of computer simulations. The geometry we consider is inspired by recent experiments probing the compressional elasticity of the bacterial nucleoid (DNA plus associated proteins), where DNA is confined into a ...
arxiv +1 more source
Evolutionary behaviour of bacterial prion-like proteins.
PLoS ONE, 2019 Prions in eukaryotes have been linked to diseases, evolutionary capacitance, large-scale genetic control and long-term memory formation. In bacteria, constructed prion-forming proteins have been described, such as the prion-forming protein recently ...
Paul M Harrison
doaj +1 more source
PLoS Biology, 2023 Animals use a variety of cell-autonomous innate immune proteins to detect viral infections and prevent replication. Recent studies have discovered that a subset of mammalian antiviral proteins have homology to antiphage defense proteins in bacteria ...
Edward M Culbertson, Tera C Levin
doaj +1 more source