Results 41 to 50 of about 7,190,308 (348)
FEMS Microbiology Letters, 2018 Virulence-associated type III secretion systems (T3SS) serve the injection of bacterial effector proteins into eukaryotic host cells. They are able to secrete a great diversity of substrate proteins in order to modulate host cell function, and have ...
Samuel Wagner +5 more
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Intracellular proteins moonlighting as bacterial adhesion factors
AIMS Microbiology, 2018 Pathogenic and commensal, or probiotic, bacteria employ adhesins on the cell surface to attach to and interact with the host. Dozens of the adhesins that play key roles in binding to host cells or extracellular matrix were originally identified as ...
Constance Jeffery
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Arginine glycosylation enhances methylglyoxal detoxification
Scientific Reports, 2021 Type III secretion system effector proteins have primarily been characterized for their interactions with host cell proteins and their ability to disrupt host signaling pathways.
Samir El Qaidi +2 more
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Subversion of the Endocytic and Secretory Pathways by Bacterial Effector Proteins
Front. Cell Dev. Biol., 2018 Intracellular bacteria have developed numerous strategies to hijack host vesicular trafficking pathways to form their unique replicative niches. To promote intracellular replication, the bacteria must interact with host organelles and modulate host ...
Mary M. Weber, R. Faris
semanticscholar +1 more source
Evolutionary behaviour of bacterial prion-like proteins.
PLoS ONE, 2019 Prions in eukaryotes have been linked to diseases, evolutionary capacitance, large-scale genetic control and long-term memory formation. In bacteria, constructed prion-forming proteins have been described, such as the prion-forming protein recently ...
Paul M Harrison
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STAS Domain Only Proteins in Bacterial Gene Regulation
Frontiers in Cellular and Infection Microbiology, 2021 Sulfate Transport Anti-Sigma antagonist domains (Pfam01740) are found in all branches of life, from eubacteria to mammals, as a conserved fold encoded by highly divergent amino acid sequences.
Brian E. Moy, J. Seshu
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SEDS proteins are a widespread family of bacterial cell wall polymerases
Nature, 2016 Elongation of rod-shaped bacteria is mediated by a dynamic peptidoglycan-synthetizing machinery called the Rod complex. Here we report that, in Bacillus subtilis, this complex is functional in the absence of all known peptidoglycan polymerases.
A. Meeske +9 more
semanticscholar +1 more source
MicroorganismsMycobacterium tuberculosis (Mtb) is the causative agent of tuberculosis, the world’s deadliest infectious disease. Mtb uses a variety of mechanisms to evade the human host’s defenses and survive intracellularly.
Bonnie J. Cuthbert +6 more
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Bacterial Signal Peptides- Navigating the Journey of Proteins
Frontiers in Physiology, 2022 In 1971, Blobel proposed the first statement of the Signal Hypothesis which suggested that proteins have amino-terminal sequences that dictate their export and localization in the cell.
Sharbani Kaushik +2 more
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Translocation of bacterial proteins?an overview
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 2004 Recent progress in the understanding of the nature of the extraordinary variety of protein translocation systems, mainly in Gram negative bacteria, is reviewed. This takes us from the insertion of proteins into the inner membrane via the sophisticated Sec apparatus, the lethal injection of Type III proteins into host cells and on to the beautiful ...
openaire +3 more sources