Results 41 to 50 of about 757,127 (284)

A histidine‐rich extension of the mitochondrial F0 subunit ATP6 from the ice worm Mesenchytraeus solifugus increases ATP synthase activity in bacteria

open access: yesFEBS Letters, EarlyView.
The glacier ice worm Mesenchytraeus solifugus survives year‐round at 0 °C. Its ATP6 subunit, which forms a regulatory component of the proton pore in mitochondrial ATP synthase, has a carboxy‐terminal extension not found in any other organism examined to date. Here, we show that fusion of this extension to the homologous AtpB protein in E. coli results
Truman Dunkley   +2 more
wiley   +1 more source

Arginine glycosylation enhances methylglyoxal detoxification

open access: yesScientific Reports, 2021
Type III secretion system effector proteins have primarily been characterized for their interactions with host cell proteins and their ability to disrupt host signaling pathways.
Samir El Qaidi   +2 more
doaj   +1 more source

STAS Domain Only Proteins in Bacterial Gene Regulation

open access: yesFrontiers in Cellular and Infection Microbiology, 2021
Sulfate Transport Anti-Sigma antagonist domains (Pfam01740) are found in all branches of life, from eubacteria to mammals, as a conserved fold encoded by highly divergent amino acid sequences.
Brian E. Moy, J. Seshu
doaj   +1 more source

Elucidation of interface interactions between a dehydratase domain and an acyl carrier protein in cremimycin polyketide synthase

open access: yesFEBS Letters, EarlyView.
In modular polyketide synthases, the dehydratase (DH) domain catalyzes the dehydration reaction of the β‐hydroxyacyl unit attached to the cognate acyl carrier protein (ACP) domain. However, it is unclear how DH interacts with ACP during the reaction. In this study, we identified DH–ACP interface residues, providing the first detailed insights into DH ...
Kaede Kotagiri   +8 more
wiley   +1 more source

Порівняльна характеристика біотехнологічних підходів до отримання рекомбінантних цитокінів людини у бактеріальних системах експресії

open access: yesInnovative Biosystems and Bioengineering, 2019
Проблематика. Цитокіни забезпечують зв’язок між клітинами і відіграють важливу роль у модуляції вродженої та адаптивної імунної відповіді. Будучи медіаторами, вони активні в дуже невеликих кількостях і впливають на безліч біологічних процесів ...
Tetiana Natochii, Valentina Motronenko
doaj   +1 more source

Bacterial Signal Peptides- Navigating the Journey of Proteins

open access: yesFrontiers in Physiology, 2022
In 1971, Blobel proposed the first statement of the Signal Hypothesis which suggested that proteins have amino-terminal sequences that dictate their export and localization in the cell.
Sharbani Kaushik   +2 more
doaj   +1 more source

Functional variation among LPMOs revealed by the inhibitory effects of cyanide and buffer ions

open access: yesFEBS Letters, EarlyView.
This study addresses the inhibition of lytic polysaccharide monooxygenases (LPMOs) by cyanide and explains how and why the magnitude of observed inhibitory effects depends on the way LPMO reactions are setup and on the type of LPMO. Enzymes known as lytic polysaccharide monooxygenases (LPMOs) are mono‐copper polysaccharide‐degrading peroxygenases that ...
Ole Golten   +10 more
wiley   +1 more source

Insertion of the FeB cofactor in cNORs lacking metal inserting chaperones

open access: yesFEBS Letters, EarlyView.
Nitric oxide reductase is an enzyme found in the bacterial denitrification pathway. The NOR active site contains a non‐heme iron, often, but not always inserted with the assistance of chaperones. Here, we study the insertion of FeB in the subfamily of cNORs lacking chaperones and found a putative channel, conserved in the family, perhaps enabling the ...
Sofia Appelgren, Pia Ädelroth
wiley   +1 more source

Dancing to Another Tune—Adhesive Moonlighting Proteins in Bacteria

open access: yesBiology, 2014
Biological moonlighting refers to proteins which express more than one function. Moonlighting proteins occur in pathogenic and commensal as well as in Gram-positive and Gram-negative bacteria.
Veera Kainulainen, Timo K. Korhonen
doaj   +1 more source

Topological defects at smectic interfaces as a potential tool for the biosensing of living microorganisms [PDF]

open access: yesarXiv, 2023
Characterizing the anchoring properties of smectic liquid crystals (LCs) in contact with bacterial solutions is crucial for developing biosensing platforms. In this study, we investigate the anchoring properties of a smectic LC when exposed to Bacillus Subtilis and Escherichia coli bacterial solutions using interfaces with known anchoring properties ...
arxiv  

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