Results 51 to 60 of about 1,243,937 (259)

Klebsiella pneumoniae, a human-dog shuttle organism for the genes of CTX-M ESBL

Scientific Reports
Antimicrobials reserved for human medicines are permitted for companion animals and it is important to understand multidrug-resistant pathogens recovered from companion animals in terms of epidemiological correlation with human pathogens and possibility ...
Eun-Jeong Yoon, You Jeong Choi, Dongju Won, Jong Rak Choi, Seok Hoon Jeong   +4 more
doaj   +1 more source

Antibiotics promote intestinal growth of carbapenem-resistant Enterobacteriaceae by enriching nutrients and depleting microbial metabolites

Nature Communications, 2023
The intestine is the primary colonisation site for carbapenem-resistant Enterobacteriaceae (CRE) and serves as a reservoir of CRE that cause invasive infections (e.g. bloodstream infections).
Alexander Y. G. Yip, Olivia G. King, Oleksii Omelchenko, Sanjana Kurkimat, Victoria Horrocks, Phoebe Mostyn, Nathan Danckert, Rohma Ghani, Giovanni Satta, Elita Jauneikaite, Frances J. Davies, Thomas B. Clarke, Benjamin H. Mullish, Julian R. Marchesi, Julie A. K. McDonald   +14 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Host-induced cell wall remodeling impairs opsonophagocytosis of Staphylococcus aureus by neutrophils

mBio
The bacterial pathogen Staphylococcus aureus responds to the host environment by increasing the thickness of its cell wall. However, the impact of cell wall thickening on susceptibility to host defenses is unclear. Using bacteria incubated in human serum,
Elizabeth V. K. Ledger, Andrew M. Edwards   +1 more
doaj   +1 more source

Microbial Communities of the Providence River [PDF]

, 2015
The Providence River has been industrialized for over one-hundred years. Industries such as oil storage and metal recycling facilities have left high levels of pollutant metals, including lead (Pb), in the soil and water.
Kratch, Jacqueline
core   +1 more source

Identification of markers associated with bacterial blight resistance loci in cowpea (Vigna unguiculata (L.) Walp.) [PDF]

, 2010
Cowpea bacterial blight (CoBB), caused by Xanthomonas axonopodis pv. vignicola (Xav), is a worldwide major disease of cowpea [Vigna unguiculata (L.) Walp.].
Agbicodo, A.C.M.E., Bandyopadhyay, R., Close, T.J., Diop, N.N., Ehlers, J.D., Fatokun, C.A., Linden, C.G., van der, Muchero, W., Roberts, P.A., Visser, R.G.F., Wydra, K.   +10 more
core   +2 more sources

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

FEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf, Nicholas F. Downing, Kaitlyn M. Mills, Samuel C. Metcalfe, Alexander E. Kritzer, Lindsey D. Mayo, Peter C. Hollenhorst   +6 more
wiley   +1 more source

Prevalence of Plasmid-Mediated Determinants With Decreased Susceptibility to Azithromycin Among Shigella Isolates in Anhui, China

Frontiers in Microbiology, 2020
ObjectiveThe aims of this study were to describe azithromycin (AZM) susceptibility patterns among Shigella isolates in Anhui, China and identify predictors of resistance with mobile element-mediated genes.MethodsA total of 517 non-duplicate Shigella ...
Yanyan Liu, Yanyan Liu, Yanyan Liu, Hongru Li, Na Lv, Yalong Zhang, Xihai Xu, Ying Ye, Ying Ye, Ying Ye, Yufeng Gao, Yufeng Gao, Yufeng Gao, Jiabin Li, Jiabin Li, Jiabin Li, Jiabin Li   +16 more
doaj   +1 more source

Resistance to Ralstonia Solanacearum of sexual hybrids between Solanum commersonii and S. tuberosum [PDF]

, 2009
This research was carried out to study the levels of bacterial wilt resistance and genetic diversity of (near) pentaploid sexual hybrids between S. commersonii (2n = 2x = 24, 1EBN) and cultivated S. tuberosum.
AVERSANO, RICCARDO, BARONE, AMALIA, CARPUTO, DOMENICO, DI MATTEO, ANTONIO, FRUSCIANTE, LUIGI, Iorizzo M., Sigillo L, ZOINA, ASTOLFO   +7 more
core   +2 more sources

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

FEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman, Anna E. Lester, Brian D. Zoltowski   +2 more
wiley   +1 more source