Results 31 to 40 of about 1,461,971 (329)
Reversible cross-tolerance to platelet-activating factor signaling by bacterial toxins
Platelets, 2021 Bacterial toxins signaling through Toll-like receptors (TLRs) are implicated in the pathogenesis of many inflammatory diseases. Among the toxins, lipopolysaccharide (LPS) exerts its action via TLR-4 while lipoteichoic acid (LTA) and bacterial ...
Kandahalli Venkataranganayaka Abhilasha +5 more
doaj +1 more source
Bacteria-derived chimeric toxins as potential anticancer agents
Frontiers in Oncology, 2022 Cancer is one of the major causes of death globally, requiring everlasting efforts to develop novel, specific, effective, and safe treatment strategies.
Saeed Khoshnood +7 more
doaj +1 more source
Bacterial toxins: Offensive, defensive, or something else altogether? [PDF]
PLoS Pathog, 2017 The secretion of proteins that damage host tissue is well established as integral to the infectious processes of many bacterial pathogens. However, recent advances in our understanding of the activity of toxins suggest that the attributes we have ...
Rudkin JK +3 more
europepmc +2 more sources
Investigation of the adsorption capacity of the enterosorbent Enterosgel for a range of bacterial toxins, bile acids and pharmaceutical drugs. [PDF]
Sci Rep, 2019 Oral intestinal adsorbents (enterosorbents) are orally administered materials which pass through the gut where they bind (adsorb) various substances. The enterosorbent Enterosgel (Polymethylsiloxane polyhdrate) is recommended as a symptomatic treatment ...
Howell CA +3 more
europepmc +2 more sources
mBio, 2021 Toxin-antitoxin modules are widespread in prokaryotes, and the capacity of toxin accumulation to increase the tolerances of bacteria to antibiotics has been well documented.
Annabel S. Lemma, Mark P. Brynildsen
doaj +1 more source
In Situ Capture of Bacterial Toxins for Antivirulence Vaccination. [PDF]
Adv Mater, 2017 Wei X +10 more
europepmc +2 more sources
Why Are Botulinum Neurotoxin-Producing Bacteria So Diverse and Botulinum Neurotoxins So Toxic?
Toxins, 2019 Botulinum neurotoxins (BoNTs) are the most lethal toxins among all bacterial, animal, plant and chemical poisonous compounds. Although a great effort has been made to understand their mode of action, some questions are still open.
Bernard Poulain, Michel R. Popoff
doaj +1 more source
Toxins, 2018 One of the numerous toxins produced by Clostridium perfringens is Clostridium perfringens enterotoxin (CPE), a polypeptide with a molecular mass of 35.5 kDa exhibiting three different domains. Domain one is responsible for receptor binding, domain two is
Roland Benz, Michel R. Popoff
doaj +1 more source
Therapeutic Uses of Bacterial Subunit Toxins
Toxins, 2021 The B subunit pentamer verotoxin (VT aka Shiga toxin-Stx) binding to its cellular glycosphingolipid (GSL) receptor, globotriaosyl ceramide (Gb3) mediates internalization and the subsequent receptor mediated retrograde intracellular traffic of the AB5 ...
Clifford Lingwood
doaj +1 more source
Targeting and inactivation of bacterial toxins by human defensins. [PDF]
Biol Chem, 2017 Kudryashova E, Seveau SM, Kudryashov DS.
europepmc +2 more sources