Results 41 to 50 of about 1,432,377 (335)
Why Are Botulinum Neurotoxin-Producing Bacteria So Diverse and Botulinum Neurotoxins So Toxic?
Toxins, 2019 Botulinum neurotoxins (BoNTs) are the most lethal toxins among all bacterial, animal, plant and chemical poisonous compounds. Although a great effort has been made to understand their mode of action, some questions are still open.
Bernard Poulain, Michel R. Popoff
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Toxins, 2018 One of the numerous toxins produced by Clostridium perfringens is Clostridium perfringens enterotoxin (CPE), a polypeptide with a molecular mass of 35.5 kDa exhibiting three different domains. Domain one is responsible for receptor binding, domain two is
Roland Benz, Michel R. Popoff
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Toxin-mediated competition in weakly motile bacteria [PDF]
2019, J. Theor. Biol. 480 , 205-217, 2019 Many bacterial species produce toxins that inhibit their competitors. We model this phenomenon by extending classic two-species Lotka-Volterra competition in one spatial dimension to incorporate toxin production by one species. Considering solutions comprising two adjacent single-species colonies, we show how the toxin inhibits the susceptible species ...
arxiv +1 more source
Two Clostridium perfringens Type E Isolates in France
Toxins, 2019 Clostridium perfringens type E is a less frequently isolated C. perfringens type and has not previously been reported in France. We have characterized two recent type E isolates, C.
Laure Diancourt +3 more
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Therapeutic Uses of Bacterial Subunit Toxins
Toxins, 2021 The B subunit pentamer verotoxin (VT aka Shiga toxin-Stx) binding to its cellular glycosphingolipid (GSL) receptor, globotriaosyl ceramide (Gb3) mediates internalization and the subsequent receptor mediated retrograde intracellular traffic of the AB5 ...
Clifford Lingwood
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CsrA and its regulators control the time-point of ColicinE2 release in Escherichia coli [PDF]
Scientific Reports 8, 6537 (2018), 2018 The bacterial SOS response is a cellular reaction to DNA damage, that, among other actions, triggers the expression of colicin - toxic bacteriocins in Escherichia coli that are released to kill close relatives competing for resources. However, it is largely unknown, how the complex network regulating toxin expression controls the time-point of toxin ...
arxiv +1 more source
Chemical warfare and survival strategies in bacterial range expansions [PDF]
J. R. Soc. Interface 11, 20140172 (2014), 2014 Dispersal of species is a fundamental ecological process in the evolution and maintenance of biodiversity. Limited control over ecological parameters has hindered progress in understanding of what enables species to colonise new area, as well as the importance of inter-species interactions.
arxiv +1 more source
Molecular Insights into the Assembly and Functional Diversification of Typhoid Toxin
mBio, 2022 Typhoid toxin is an A2B5 protein toxin and an important virulence factor for the human-adapted bacterial pathogen Salmonella enterica serovar Typhi, the causative agent of typhoid fever. Typhoid toxin contains two enzymatic subunits, PltA and CdtB, which
Xiaoyu Liu +9 more
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Evolution and stability of altruist strategies in microbial games [PDF]
Physical Review E 85 (2012) 011914, 2010 When microbes compete for limited resources, they often engage in chemical warfare using bacterial toxins. This competition can be understood in terms of evolutionary game theory (EGT). We study the predictions of EGT for the bacterial "suicide bomber" game in terms of the phase portraits of population dynamics, for parameter combinations that cover ...
arxiv +1 more source
mBio, 2021 Many bacterial species interact via direct cell-to-cell contact using CDI systems, which provide a mechanism to inject toxins that inhibit bacterial growth into one another.
Allison M. Jones +7 more
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