Results 41 to 50 of about 235,361 (338)
A widespread family of polymorphic toxins encoded by temperate phages
BMC Biology, 2017 Background Polymorphic toxins (PTs) are multi-domain bacterial exotoxins belonging to distinct families that share common features in terms of domain organization.
Anne Jamet +7 more
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Gut-Derived Metabolites and Their Role in Immune Dysfunction in Chronic Kidney Disease
Toxins, 2020 Several of the uremic toxins, which are difficult to remove by dialysis, originate from the gut bacterial metabolism. This opens opportunities for novel targets trying to decrease circulating levels of these toxins and their pathophysiological effects ...
Griet Glorieux +2 more
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The Biological Properties of Bacterial Toxins
Вестник войск РХБ защитыKnowledge of the biological properties of bacterial toxins is constantly being updated. Over the past two decades, the research interest has shifted from natural toxins to their genetically modified derivatives.
M. V. Supotnitskiy
doaj +1 more source
Autoproteolytic Activation of Bacterial Toxins
Toxins, 2010 Protease domains within toxins typically act as the primary effector domain within target cells. By contrast, the primary function of the cysteine protease domain (CPD) in Multifunctional Autoprocessing RTX-like (MARTX) and Clostridium sp.
Aimee Shen
doaj +1 more source
Synergism between fungal enzymes and bacterial antibiotics may enhance biocontrol [PDF]
, 2002 The interactions between biocontrol fungi and bacteria may play a key role in the natural process of biocontrol, although the molecular mechanisms involved are still largely unknown.
FOGLIANO, VINCENZO +3 more
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Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Toxins, 2020 This 26th edition of the annual Meeting on Toxinology (RT26) of the SFET (http://sfet.asso.fr/international) was held at the Institut Pasteur of Paris on 4−5 December 2019 [...]
Pascale Marchot +3 more
doaj +1 more source
, 2015 Bacteriocins are peptide-derived molecules produced by bacteria, whose recently-discovered functions include virulence factors and signalling molecules as well as their better known roles as antibiotics.
Freed, Stefan D +3 more
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Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
Shiga Toxin Detection Methods : A Short Review [PDF]
, 2013 The Shiga toxins comprise a family of related protein toxins secreted by certain types of bacteria. Shigella dysenteriae, some strain of Escherichia coli and other bacterias can express toxins which caused serious complication during the infection. Shiga
González-Aguilar, G. +1 more
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