Results 211 to 220 of about 64,640 (278)

The Forgotten History of Bacteriophages in Bulgaria: An Overview and Molecular Perspective on Their Role in Addressing Antibiotic Resistance and Therapy. [PDF]

Viruses
Kalvatchev N, Khanbabapour T, Sakkeer A, Tsekov I, Delchev Y, Strateva T.   +5 more
europepmc   +1 more source

Tailoring Vascular‐Immune Homeostasis via Manganese‐DNA Complex‐Armed Immunogenic Extracellular Vesicles for Pancreatic Cancer Immunotherapy

Advanced Science, EarlyView.
This study demonstrates that Mn2⁺–tumor DNA complexes encapsulated in dendritic cell (DC)– derived immunogenic extracellular vesicles (EVDC@Mn‐DNA) act as a DC‐specific cGAS– STING activator. EVDC@Mn‐DNA treatment enhances intratumoral DC activation, improves tumor vascular function, promotes CD8⁺ T cell activity, and suppresses pancreatic tumor growth,
Xue Jiang, Lihuan Shang, Xiaochun Chen, Xiangzhan Kong, Xiaojuan Wang, Linjia Jiang, Huiying Zhao, Yafeng Zhu, Cheng Huang, Shiyi Deng, Rui Zhang, Minghui Wang, Haoming Lin, Ping‐Pui Wong   +13 more
wiley   +1 more source

Genome-wide approaches to bacterial strain typing: a history and review of recent methodological advances. [PDF]

Curr Opin Infect Dis
Shropshire WC, Hanson BM, Shelburne SA.
europepmc   +1 more source

Engineered Living Systems With Self‐Organizing Neural Networks: From Anatomy to Behavior and Gene Expression

Advanced Science, EarlyView.
Ectodermal tissue excised from Xenopus embryos self‐organizes into a three‐dimensional mucociliary organoid. Here, we generate a neural variant, termed neurobot, by implanting neural precursor cells. Neurobots develop mature neurons, adopt distinct morphologies, exhibit more complex motility, and respond differentially to neuroactive compounds. Imaging
Haleh Fotowat, Laurie O'Neill, Léo Pio‐Lopez, Megan M. Sperry, Patrick Erickson, Tiffany Lin, Michael Levin   +6 more
wiley   +1 more source

Molecular techniques and microscopy in bacterial detection and typing

, 2007
openaire   +3 more sources

<i>Pa</i>REx: an open-source pipeline for the automated analysis of <i>Pseudomonas aeruginosa</i> resistomes from whole-genome sequences. [PDF]

Antimicrob Agents Chemother
López-Causapé C, Bonet M, Taltavull B, Medina-Retiga P, Sastre-Femenía MA, Cortés-Lara S, Gomis-Font MA, Gomez-Romano F, Oliver A.   +8 more
europepmc   +1 more source

A Bifunctional T3SS‐Effector Simultaneously Cleaves Host MAP Kinase and Inhibits PPM1A Phosphatase

Advanced Science, EarlyView.
Pathogenic bacteria exploit the metalloprotease effector NleD to subvert host defenses. Structural, biochemical, and infection analyses reveal a bifunctional mechanism by which NleD binds and inhibits the host phosphatase PPM1A while preserving its proteolytic activity against MAPKs.
Yaakov Socol, Lihi Gur‐Arie, Netanel Tzarum, Tamara Wellins, Naama Katsowich, Miriam Ravins, Michal Bejerano‐Sagie, Klil Cohen, Oded Livnah, Joshua N. Adkins, Ernesto Nakayasu, Alexei Savchenko, Yeu Khai Choong, Nikhil Kumar Tulsian, Saturo Machida, Sigal Ben‐Yehuda, Yael Litvak, J. Sivaraman, Ilan Rosenshine   +18 more
wiley   +1 more source

Application of next-generation sequencing to investigate a Serratia marcescens outbreak in a neonatal intensive care unit. [PDF]

Antimicrob Resist Infect Control
Bulfoni M, Gualandi N, Krpan B, Vesca G, Lombardo C, Marzinotto S, Marcon B, Faruzzo A, Cargnelutti C, Virgili G, Cocconi R, Pipan C, Curcio F.   +12 more
europepmc   +1 more source

Detection of Protein–Protein Interactions in Escherichia coli With Single Molecule Sensitivity

Advanced Science, EarlyView.
This article describes a regulatory circuit in Escherichia coli able to detect protein–protein interactions with exquisite sensitivity. The interaction between two hybrid proteins fused to Bordetella pertussis adenylate cyclase and its activator calmodulin triggers a potent cyclic AMP signaling cascade.
Marilyne Davi, Daniel Ladant
wiley   +1 more source

Novel, rapid, and reliable typing of vancomycin-resistant <i>Enterococcus faecium</i> CC17/ST80 strains using MALDI-TOF MS. [PDF]

Microbiol Spectr
Huber S, Brühwasser C, Eisele D, Lass-Flörl C, Fuchs S, Govrins M.   +5 more
europepmc   +1 more source