Results 241 to 250 of about 64,640 (278)

Embedded CRISPRi Enhances Gene‐Silencing Efficiency in Drosophila

open access: yesAdvanced Science, EarlyView.
Current CRISPR interference (CRISPRi) technology in Drosophila has limited efficiency. This study introduces the emCRISPRi platform, which significantly enhances transcriptional silencing efficacy by embedding inhibitory domains within the dCas9 architecture.
Pengchong Fu   +7 more
wiley   +1 more source

Shaping the future of <i>Leptospira</i> serotyping. [PDF]

open access: yesJ Med Microbiol
Giraud-Gatineau A   +5 more
europepmc   +1 more source

Mechanostimulatory Cues Determine Intestinal Fibroblast Fate and Profibrotic Remodeling in a Physiodynamic Human Gut‐on‐a‐Chip

open access: yesAdvanced Science, EarlyView.
A healthy gut barrier shields underlying fibroblasts from luminal shear forces, illustrating that “good fences make good neighbors.” Barrier damage exposes fibroblasts to shear stress, inducing cell death and the emergence of stress‐adapted, profibrotic fibroblasts. Sustained shear exposure promotes the formation of stiff aggregates of mechanoadapative
Soyoun Min   +6 more
wiley   +1 more source

Detection of a <i>Serratia sarumanii</i> outbreak in neonatal intensive care units using SaTScan and whole genome sequencing, Philippines, 2022. [PDF]

open access: yesWestern Pac Surveill Response J
Godin GV   +20 more
europepmc   +1 more source

Home - About - Disclaimer - Privacy