Results 51 to 60 of about 27,960 (233)

Bacteriological and molecular identification of Bartonella species in cats from different regions of China. [PDF]

PLoS Neglected Tropical Diseases, 2011
With the improvements in diagnostic techniques, Bartonella henselae (B. henselae) infection has recently been recognized to cause a widening spectrum of diseases. Cats are the natural reservoir hosts of B. henselae.
Congli Yuan, Caixia Zhu, Yanbing Wu, Xueying Pan, Xiuguo Hua   +4 more
doaj   +1 more source

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

FEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman, Katarzyna Stapor, Leszek Konieczny, Krzysztof Gądek, Piotr Nowakowski   +4 more
wiley   +1 more source

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

FEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel, Carlos DeOcesano Pereira, Aline Ramos Maia Lobba, Melissa Regina Fessel, Ana Marisa Chudzinski‐Tavassi   +4 more
wiley   +1 more source

Antimicrobial resistance profiles of Escherichia coli based on molecular typing and public health prevention and control strategy

陆军军医大学学报
Objective The pathogenic characteristics of Escherichia coli (E.coli) in bacterial infections were analyzed using a combination of multiple molecular typing techniques in order to provide evidence for the management of clinical medication safety ...
ZONG Hua, ZONG Hua, LI Caiyun, LI Caiyun
doaj   +1 more source

Combined 5‐aminolevulinic acid and ferric ammonium citrate treatment promotes hair follicle growth by activating dermal papilla cells

FEBS Open Bio, EarlyView.
5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley   +1 more source

Comparison of Types of Etanol Solvents, Antibacterial Test Methods, and Bacterial Inoculation Techniques used to Determine The Antibacterial Activity of Turmeric Rhizome Ethanol Extract Against Escherichia coli

BERKALA SAINSTEK
Turmeric is a plant that has antibacterial properties due to the curcumin content in plant parts such as rhizomes. Antibacterial testing of plant extracts is influenced by several factors. This study aims to determine the effect of the type of ethanol solvents, antibacterial test methods, and inoculation techniques used on the antibacterial activity of
Endang Soesetyaningsih, null Azizah
openaire   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Transposon Insertion Sequencing Elucidates Novel Gene Involvement in Susceptibility and Resistance to Phages T4 and T7 in Escherichia coli O157

mBio, 2018
Experiments using bacteriophage (phage) to infect bacterial strains have helped define some basic genetic concepts in microbiology, but our understanding of the complexity of bacterium-phage interactions is still limited.
Lauren A. Cowley, Alison S. Low, Derek Pickard, Christine J. Boinett, Timothy J. Dallman, Martin Day, Neil Perry, David L. Gally, Julian Parkhill, Claire Jenkins, Amy K. Cain   +10 more
doaj   +1 more source

Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10

FEBS Open Bio, EarlyView.
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee, Ga Seul Lee, JinHan Kim, Kwang‐Hyun Park, Seong‐Ryung Go, Jeong Hee Moon, Eui‐Jeon Woo   +6 more
wiley   +1 more source

Omics, epidemiology and integrated approach for the coexistence with bacterial canker of kiwifruit, caused by Pseudomonas syringae pv. actinidiae

Italian Journal of Agronomy, 2014
Bacterial canker of kiwifruit, caused by Pseudomonas syringae pv. actinidiae, is a destructive disease found in all major areas of production of green-fleshed (Actinidia deliciosa) and yellow-fleshed (A.
Marco Scortichini, Patrizia Ferrante, Simone Marcelletti, Milena Petriccione   +3 more
doaj   +1 more source