Nanobodies as potential tools for microbiological testing of live biotherapeutic products
Nanobodies are highly specific binding domains derived from naturally occurring single chain camelid antibodies. Live biotherapeutic products (LBPs) are biological products containing preparations of live organisms, such as Lactobacillus, that are ...
Robert J. Dorosky+9 more
doaj +1 more source
A lucky career in bacterial vaccines [PDF]
(2012). A lucky career in bacterial vaccines. Human Vaccines & Immunotherapeutics: Vol. 8, No. 4, pp. 420-422.
openaire +3 more sources
Spirochetal Lipoproteins and Immune Evasion. [PDF]
Spirochetes are a major threat to public health. However, the exact pathogenesis of spirochetal diseases remains unclear. Spirochetes express lipoproteins that often determine the cross talk between the host and spirochetes.
Boyadjian, Ani+2 more
core +1 more source
Adjusting Cell‐Surface Interactions Through a Covalent Immobilization of Biomolecules
This review presents an overview of current and emerging immobilization techniques coupled with an in‐depth investigation of the underlying mechanisms governing the activity and stability of covalently immobilized biomolecules. The aim of this study is to serve as a guide for the development of long‐lasting biomedical coatings with versatile biological
Sara Shakibania+2 more
wiley +1 more source
The Unexpected Impact of Vaccines on Secondary Bacterial Infections Following Influenza.
Influenza virus infections remain a significant health burden worldwide, despite available vaccines. Factors that contribute to this include a lack of broad coverage by current vaccines and continual emergence of novel virus strains. Further complicating
A. Smith, Victor C. Huber
semanticscholar +1 more source
Setting priorities for development of emerging interventions against childhood pneumonia, meningitis and influenza [PDF]
WAcute lower respiratory infections, which broadly include pneumonia and bronchiolitis, are still the leading cause of childhood mortality. ALRI contributed to 18% of all deaths in children younger than five years of age in 2008, and the main pathogens ...
Black+21 more
core +2 more sources
This review focuses on the application of synthetic biodegradable microarray patches (MAPs) in sustained drug delivery. Compared to conventional MAPs which release drugs into the skin in an immediate manner, these implantable MAPs release drugs into skin microcirculation gradually as the biodegradable polymers degrade, thus offering sustained release ...
Li Zhao+6 more
wiley +1 more source
Identification of specific antigens responsible for the ability of complex immunogens to induce protection is a major goal in development of bacterial vaccines.
S. M. Albarrak+8 more
semanticscholar +1 more source
Novel particulate vaccine candidates recombinantly produced by pathogenic and nonpathogenic bacterial hosts : a thesis presented in partial fulfillment of the requirements for the degree of Doctor of Philosophy in Microbiology at Massey University, Manawatu, New Zealand. [PDF]
Polyhydroxyalkanoates (PHAs) are biopolyesters synthesized as small spherical cytoplasmic inclusion bodies by a range of bacteria. Recently, PHA beads have been investigated for use as a vaccine delivery platform by using engineered heterologous ...
Lee, Jason Wong
core
Public health approach to prevent cervical cancer in HIV-infected women in Kenya : issues to consider in the design of prevention programs [PDF]
Women living with HIV in Africa are at increased risk to be co-infected with Human Papilloma Virus (HPV), persistent high risk (HR) HPV infection and bacterial vaginosis (BV), which compounds HPV persistence, thereby increasing the risk for cervical ...
Callens, Steven+4 more
core +3 more sources