Results 201 to 210 of about 94,986 (281)

Harnessing nanomaterials to precisely regulate the immunosuppressive tumor microenvironment for enhanced immunotherapy

open access: yesBMEMat, EarlyView.
The immunosuppressive tumor microenvironment, characterized by hypoxia, redox imbalance, elevated interstitial fluid pressure, and acidity, was comprehensively elucidated. This review discussed the etiology and consequences of the characteristics of the immunosuppressive tumor microenvironment, and analyzed the recent advancements in nanomaterials for ...
Wen Zhang   +7 more
wiley   +1 more source

Transcriptomic functional characterization of recombinant adeno‐associated virus producing cell line adapted to suspension‐growth

open access: yesBiotechnology Progress, EarlyView.
Abstract Recombinant adeno‐associated virus (rAAV) is a widely used delivery vehicle in gene therapy. A scalable production technology is essential for its wide clinical applications. We have taken a synthetic biology approach to generate HEK293‐based cell lines which harbor integrated genetic elements encoding essential AAV and adenoviral helper ...
Han‐Jung Kuo   +6 more
wiley   +1 more source

Malaria Vaccine Development: Are Bacterial Flagellin Fusion Proteins the Bridge between Mouse and Humans? [PDF]

open access: gold, 2011
Daniel Y. Bargieri   +5 more
openalex   +1 more source

Hands‐free from inoculation to harvest: Microbial fermentation with multivariate model to automate induction of recombinant protein expression

open access: yesBiotechnology Progress, EarlyView.
Abstract Industrial fermentation continually improves biological process control for a wide range of microorganisms used in multi‐billion‐dollar industries including industrial enzymes, pharmaceuticals, foods, beverages, commodity chemicals, and bioenergy.
Jennifer Reid   +6 more
wiley   +1 more source

Promising Prodiginins Biological Activities

open access: yesChemistry &Biodiversity, EarlyView.
ABSTRACT Prodiginins are a large family of at least 34 pyrrolic compounds, including the well‐studied red pigment prodigiosin. Prodiginins are produced by several microorganisms displaying broad biological activities, including antimicrobial, antiviral, antiparasitic, antiproliferative, and immunosuppressive activities.
María F. Ladetto   +6 more
wiley   +1 more source

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