Results 31 to 40 of about 213,855 (329)

The History, Present and Future of Allergen Standardization in the United States and Europe

open access: yesFrontiers in Immunology, 2021
The topic of standardization in relation to allergen products has been discussed by allergists, regulators, and manufacturers for a long time. In contrast to synthetic medicinal products, the natural origin of allergen products makes the necessary ...
Julia Zimmer   +5 more
doaj   +1 more source

Public health approach to prevent cervical cancer in HIV-infected women in Kenya : issues to consider in the design of prevention programs [PDF]

open access: yes, 2017
Women living with HIV in Africa are at increased risk to be co-infected with Human Papilloma Virus (HPV), persistent high risk (HR) HPV infection and bacterial vaginosis (BV), which compounds HPV persistence, thereby increasing the risk for cervical ...
Callens, Steven   +4 more
core   +3 more sources

A human Lyme disease vaccine: two steps forward on the path to prevention

open access: yesExpert Review of Vaccines
Introduction Lyme disease is caused by the tick-borne spirochete pathogen Borrelia burgdorferi sensu lato (s.l.). Outer surface protein A (OspA) is expressed by B. burgdorferi s.l.
Raphael Simon   +3 more
doaj   +1 more source

Toward an Improved Meningococcal Serogroup B Assay

open access: yesmBio, 2018
Because of diverse sequences and differential expression of surface structures on individual invasive Neisseria meningitidis serogroup B (MenB) strains, predicting the efficacy of MenB vaccines using traditional human serum bactericidal assays (hSBA) is ...
Jan Poolman
doaj   +1 more source

PECULIARITIES OF CULTIVATION OF HAEMOPHILUS INFLUENZAE TYPE B STRAINS - PRODUCERS OF POLYRIBOSYLRIBITOL PHOSPHATE - THE MAIN COMPONENT OF POLYSACCHARIDE VACCINES

open access: yesФармация и фармакология (Пятигорск), 2017
One of the up-to-date challenges of modern immunobiotechnology is the development and introduction of an effective vaccine against the infection caused by the bacterium Haemophilus influenza, type b (Hib). The main active substance of the vaccine against
E. L. Salimova   +4 more
doaj   +1 more source

Clinical burden of invasive Escherichia coli disease among older adult patients treated in hospitals in the United States

open access: yesBMC Infectious Diseases, 2023
Background Invasive extraintestinal pathogenic Escherichia coli disease (IED) can lead to severe outcomes, particularly among older adults. However, the clinical burden of IED in the U.S. has not been well characterized.
Luis Hernandez-Pastor   +9 more
doaj   +1 more source

Bordetella parapertussis Survives inside Human Macrophages in Lipid Raft-Enriched Phagosomes [PDF]

open access: yes, 2014
Bordetella parapertussis is a human pathogen that causes whooping cough. The increasing incidence of B. parapertussis has been attributed to the lack of cross protection induced by pertussis vaccines. It was previously shown that B. parapertussis is able
Gorgojo, Juan Pablo   +2 more
core   +3 more sources

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

open access: yesFEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo   +2 more
wiley   +1 more source

A SpA+LukAB vaccine targeting Staphylococcus aureus evasion factors restricts infection in two minipig infection models

open access: yesnpj Vaccines
Staphylococcus aureus is a major cause of bacterial infection-related deaths. Increasing antimicrobial resistance highlights the urgent need for effective preventative strategies.
Jan T. Poolman   +18 more
doaj   +1 more source

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