Results 31 to 40 of about 112,154 (311)

Bacterial surface proteins and vaccines [PDF]

open access: yesF1000 Biology Reports, 2010
Surface-associated proteins play a key role in bacterial physiology and pathogenesis and are the major targets for vaccine development. Recent advances in defining the proteins associated with, and protruding out of, bacterial cells to a high level of accuracy are substantially contributing to accelerating the process of vaccine target identification ...
openaire   +3 more sources

Do smaller chicken farms use more antibiotics? Evidence of antibiotic diffusion from Nigeria

open access: yesAgribusiness, Volume 39, Issue 1, Page 242-262, Winter 2023., 2023
Abstract Farmers across the world have been using antibiotics in poultry production for both therapeutic and nontherapeutic purposes since the mid 1900s. The literature on antibiotic diffusion and intensification is largely focused on developed countries in North America and Western Europe.
Charuta M. Parkhi   +2 more
wiley   +1 more source

PECULIARITIES OF CULTIVATION OF HAEMOPHILUS INFLUENZAE TYPE B STRAINS - PRODUCERS OF POLYRIBOSYLRIBITOL PHOSPHATE - THE MAIN COMPONENT OF POLYSACCHARIDE VACCINES

open access: yesФармация и фармакология (Пятигорск), 2017
One of the up-to-date challenges of modern immunobiotechnology is the development and introduction of an effective vaccine against the infection caused by the bacterium Haemophilus influenza, type b (Hib). The main active substance of the vaccine against
E. L. Salimova   +4 more
doaj   +1 more source

Clinical burden of invasive Escherichia coli disease among older adult patients treated in hospitals in the United States

open access: yesBMC Infectious Diseases, 2023
Background Invasive extraintestinal pathogenic Escherichia coli disease (IED) can lead to severe outcomes, particularly among older adults. However, the clinical burden of IED in the U.S. has not been well characterized.
Luis Hernandez-Pastor   +9 more
doaj   +1 more source

Fluorine‐Directed Automated Mannoside Assembly

open access: yesAngewandte Chemie International Edition, Volume 62, Issue 3, January 16, 2023., 2023
Motivated by the importance of fluorination in drug discovery, fluorine‐directed automated glycan assembly (AFGA) is disclosed. This strategy leverages the C(sp3)−F bond at C2 to enable α‐stereocontrolled glycosylation that eliminates the reliance on O‐based directing groups.
Charlotte S. Teschers, Ryan Gilmour
wiley   +1 more source

IMMUNOGENICITY OUTCOMES OF A RANDOMIZED, MULTICENTER, INTERVENTIONAL, FIRST-IN-HUMAN, PHASE 1/2A STUDY OF VAC52416 (EXPEC10V), A VACCINE CANDIDATE FOR THE PREVENTION OF INVASIVE ESCHERICHIA COLI DISEASE

open access: yesInternational Journal of Infectious Diseases, 2023
Intro: The safety, reactogenicity, and immunogenicity of VAC52416 (ExPEC10V), a vaccine candidate to prevent invasive Escherichia coli disease, was assessed in a phase 1/2a study (NCT03819049). Results from Cohort 1 have been presented. Here, we describe
C. Fierro   +9 more
doaj  

Toward an Improved Meningococcal Serogroup B Assay

open access: yesmBio, 2018
Because of diverse sequences and differential expression of surface structures on individual invasive Neisseria meningitidis serogroup B (MenB) strains, predicting the efficacy of MenB vaccines using traditional human serum bactericidal assays (hSBA) is ...
Jan Poolman
doaj   +1 more source

DNA vaccines for bacterial infections

open access: yesImmunology & Cell Biology, 1997
DNA vaccines are an exciting development in vaccine technology which may have a special role in preventing viral infections and as ‘theracines’ for cancer. Their use in preventing bacterial infections has, by comparison, been less well documented.
Strugnell, RA   +7 more
openaire   +5 more sources

TECHNOLOGY OF OBTAINING POLYRIBOSYLRIBITOL PHOSPHATE AS AN ACTIVE PHARMACEUTICAL INGREDIENT FOR THE PRODUCTION OF POLYSACCHARIDE VACCINES

open access: yesФармация и фармакология (Пятигорск), 2018
Despite the world practice, in the Russian Federation immunization against hemophilic infection is carried out only for the children from risk groups, which may be due to the lack of production of this vaccine in the Russian Federation.
E. L. Salimova   +3 more
doaj   +1 more source

Tularemia live vaccine as a modifier of genotoxic and carcinogenic action of environmental factors [PDF]

open access: yesArchive of Oncology, 2002
In this review we presented the data concerning the influence of tularemia live vaccine (TLV, produced in the USSR and Russia) on mutagenesis and carcinogenesis.
Nersesyan Armen K.   +2 more
doaj   +1 more source

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