Results 31 to 40 of about 94,986 (281)

In vivo testing of novel vaccine prototypes against Actinobacillus pleuropneumoniae [PDF]

open access: yes, 2018
Actinobacillus pleuropneumoniae (A. pleuropneumoniae) is a Gram-negative bacterium that represents the main cause of porcine pleuropneumonia in pigs, causing significant economic losses to the livestock industry worldwide. A.
A Hensel   +55 more
core   +3 more sources

Toward an Improved Meningococcal Serogroup B Assay

open access: yesmBio, 2018
Because of diverse sequences and differential expression of surface structures on individual invasive Neisseria meningitidis serogroup B (MenB) strains, predicting the efficacy of MenB vaccines using traditional human serum bactericidal assays (hSBA) is ...
Jan Poolman
doaj   +1 more source

Clinical burden of invasive Escherichia coli disease among older adult patients treated in hospitals in the United States

open access: yesBMC Infectious Diseases, 2023
Background Invasive extraintestinal pathogenic Escherichia coli disease (IED) can lead to severe outcomes, particularly among older adults. However, the clinical burden of IED in the U.S. has not been well characterized.
Luis Hernandez-Pastor   +9 more
doaj   +1 more source

Rethinking the role of alpha toxin in Clostridium perfringens-associated enteric diseases : a review on bovine necro-haemorrhagic enteritis [PDF]

open access: yes, 2017
Bovine necro-haemorrhagic enteritis is an economically important disease caused by Clostridium perfringens type A strains. The disease mainly affects calves under intensive rearing conditions and is characterized by sudden death associated with small ...
Deprez, Piet   +6 more
core   +3 more sources

DNA vaccines for bacterial infections

open access: yesImmunology & Cell Biology, 1997
DNA vaccines are an exciting development in vaccine technology which may have a special role in preventing viral infections and as ‘theracines’ for cancer. Their use in preventing bacterial infections has, by comparison, been less well documented.
Strugnell, RA   +7 more
openaire   +5 more sources

IMMUNOGENICITY OUTCOMES OF A RANDOMIZED, MULTICENTER, INTERVENTIONAL, FIRST-IN-HUMAN, PHASE 1/2A STUDY OF VAC52416 (EXPEC10V), A VACCINE CANDIDATE FOR THE PREVENTION OF INVASIVE ESCHERICHIA COLI DISEASE

open access: yesInternational Journal of Infectious Diseases, 2023
Intro: The safety, reactogenicity, and immunogenicity of VAC52416 (ExPEC10V), a vaccine candidate to prevent invasive Escherichia coli disease, was assessed in a phase 1/2a study (NCT03819049). Results from Cohort 1 have been presented. Here, we describe
C. Fierro   +9 more
doaj  

TECHNOLOGY OF OBTAINING POLYRIBOSYLRIBITOL PHOSPHATE AS AN ACTIVE PHARMACEUTICAL INGREDIENT FOR THE PRODUCTION OF POLYSACCHARIDE VACCINES

open access: yesФармация и фармакология (Пятигорск), 2018
Despite the world practice, in the Russian Federation immunization against hemophilic infection is carried out only for the children from risk groups, which may be due to the lack of production of this vaccine in the Russian Federation.
E. L. Salimova   +3 more
doaj   +1 more source

Spirochetal Lipoproteins and Immune Evasion. [PDF]

open access: yes, 2017
Spirochetes are a major threat to public health. However, the exact pathogenesis of spirochetal diseases remains unclear. Spirochetes express lipoproteins that often determine the cross talk between the host and spirochetes.
Boyadjian, Ani   +2 more
core   +1 more source

A METHOD FOR STANDARDIZING BACTERIAL VACCINES [PDF]

open access: yesJAMA: The Journal of the American Medical Association, 1913
The following method is presented as a convenient means for determining approximately the amount of bacterial substance in suspensions used as vaccines. It consists in measuring the volume of the moist bacteria after centrifugalization in a tube with a graduated capillary tip.
openaire   +2 more sources

PECULIARITIES OF CULTIVATION OF HAEMOPHILUS INFLUENZAE TYPE B STRAINS - PRODUCERS OF POLYRIBOSYLRIBITOL PHOSPHATE - THE MAIN COMPONENT OF POLYSACCHARIDE VACCINES

open access: yesФармация и фармакология (Пятигорск), 2017
One of the up-to-date challenges of modern immunobiotechnology is the development and introduction of an effective vaccine against the infection caused by the bacterium Haemophilus influenza, type b (Hib). The main active substance of the vaccine against
E. L. Salimova   +4 more
doaj   +1 more source

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