Results 31 to 40 of about 39,260 (206)

Development of Class IIa Bacteriocins as Therapeutic Agents

open access: yesInternational Journal of Microbiology, 2012
Class IIa bacteriocins have been primarily explored as natural food preservatives, but there is much interest in exploring the application of these peptides as therapeutic antimicrobial agents.
Christopher T. Lohans, John C. Vederas
doaj   +1 more source

Efficient Exploitation of Multiple Novel Bacteriocins by Combination of Complete Genome and Peptidome

open access: yesFrontiers in Microbiology, 2018
Backgroud: The growing emergence of antibiotic-resistant pathogens including the most dangerous superbugs requires quick discovery of novel antibiotics/biopreservatives for human health and food safety. Bacteriocins, a subgroup of antimicrobial peptides,
Lanhua Yi, Lingli Luo, Xin Lü
doaj   +1 more source

Exploring the Therapeutic Potenital of the Leaderless Enterocins K1 and EJ97 in the Treatment of Vancomycin-Resistant Enterococcal Infection

open access: yesFrontiers in Microbiology, 2021
The membrane-bound protease Eep is an important virulence factor in pathogenic enterococci. The protein is involved in stress response via the RIP pathway which is crucial for pathogenic enterococci to evade host immune attacks during infection.
Ingvild Reinseth   +3 more
doaj   +1 more source

Impact of Environmental Factors on Bacteriocin Promoter Activity in Gut-Derived Lactobacillus salivarius [PDF]

open access: yes, 2015
peer-reviewedBacteriocin production is regarded as a desirable probiotic trait that aids in colonization and persistence in the gastrointestinal tract (GIT).
Cotter, Paul D.   +6 more
core   +1 more source

New insights into enterocin CRL35: mechanism of action and immunity revealed by heterologous expression in Escherichia coli [PDF]

open access: yes, 2017
The role of the class IIa bacteriocin membrane receptor protein remains unclear, and the following two different mechanisms have been proposed: the bacteriocin could interact with the receptor changing it to an open conformation or the receptor might act
Acuña, Leonardo   +6 more
core   +1 more source

Bacteriocin Production by Beta-Hemolytic Streptococci

open access: yesPathogens, 2021
Beta-hemolytic streptococci cause a variety of infectious diseases associated with high morbidity and mortality. A key factor for successful infection is host colonization, which can be difficult in a multispecies environment.
Verena Vogel, Barbara Spellerberg
doaj   +1 more source

Genome comparison and physiological characterization of eight Streptococcus thermophilus strains isolated from Italian dairy products [PDF]

open access: yes, 2017
Eight Streptococcus thermophilus strains of dairy origin isolated in Italy were chosen to investigate autochthonous bacterial diversity in this important technological species. In the present study a comparative analysis of all the 17 S.
Campanaro, Stefano   +5 more
core   +1 more source

Bacteriocins: An Overview of Antimicrobial, Toxicity, and Biosafety Assessment by in vivo Models

open access: yesFrontiers in Microbiology, 2021
The world is facing a significant increase in infections caused by drug-resistant infectious agents. In response, various strategies have been recently explored to treat them, including the development of bacteriocins.
Diego Francisco Benítez-Chao   +7 more
doaj   +1 more source

A large scale prediction of bacteriocin gene blocks suggests a wide functional spectrum for bacteriocins

open access: yes, 2015
Bacteriocins are peptide-derived molecules produced by bacteria, whose recently-discovered functions include virulence factors and signalling molecules as well as their better known roles as antibiotics.
Freed, Stefan D   +3 more
core   +1 more source

Current review of genetically modified lactic acid bacteria for the prevention and treatment of colitis using murine models [PDF]

open access: yes, 2015
Inflammatory Bowel Diseases (IBD) are disorders of the gastrointestinal tract characterized by recurrent inflammation that requires lifelong treatments.
Azevedo, Vasco   +7 more
core   +1 more source

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