Results 31 to 40 of about 14,022 (256)

Disrupting Helicobacter pylori Iron Homeostasis With Bismuth Nanodrug‐Mediated Nutritional Trap for Targeted Gastric Infection Therapy

Advanced Science, EarlyView.
A “nutritional trap” strategy centered on disrupting bacterial iron homeostasis is proposed. The synthesized Bi‐TP@FU (TBF) can target Helicobacter pylori, interfere with the bacterial iron uptake and utilization processes to disrupt its iron homeostasis, induce bacterial death, and meanwhile preserve the balance of the intestinal flora.
Tianye Fang, Jinzhe Tong, Feng Feng, Cong Liu, Chang Shu, Jiaying Zhu, Shibo Zhang, Shuyue Deng, Wanchao Zuo, Yuhan Song, Jun Yang, Yanmin Ju, Yingying Xing, Jianjun Dai   +13 more
wiley   +1 more source

Quality Assessment of Some Springs in the Awing Community, Northwest Cameroon, and Their Health Implications

Journal of Chemistry, 2017
Some springs in Awing, North West Cameroon, were assessed in order to ascertain their quality for human consumption. Achialum, Meupi, and Ala’amiti quarters in Awing depend on springs as the major source of drinking water and inhabitants consume it in ...
Nelson Alakeh Mofor, Estella Buleng Tamungang Njoyim, Antoine David Mvondo-Zé   +2 more
doaj   +1 more source

QRICH1 Disrupts Endoplasmic Reticulum Homeostasis and Amplifies NF‐κB Signaling in Periodontal Ligament Stem Cells to Exacerbate Diabetic Periodontitis

Advanced Science, EarlyView.
QRICH1 has been established as a key factor contributing to impaired osteogenic potential and accelerated apoptosis of PDLSCs in diabetic periodontitis. QRICH1 not only significantly enhances UPR‐associated apoptotic signaling but also amplifies NF‐κB‐mediated inflammatory responses. Its inhibition restores osteogenic capacity and reduces alveolar bone
Han Li, Xiaoyu Yang, He Wang, Yunchun Kuang, Yiyao Hu, Houxuan Li, Shuhong Li, Deping Zeng, Jie Li, Jinlin Song   +9 more
wiley   +1 more source

Bacteriological Quality of Bottled Drinking Water and Municipal Tap Water in Northeastern Ethiopia

Frontiers in Environmental Science, 2022
Objective: Water-borne diseases cause high morbidity and mortality in developing countries, like Ethiopia. Diarrheal disease and typhoid are one of the top five diseases that cause significant public health burden and economic cost in Dessie city.
Awoke Keleb, Ayechew Ademas, Tadesse Sisay, Mistir Lingerew, Metadel Adane   +4 more
doaj   +1 more source

Harmonizing Rigidity and Flexibility: Embedding COF Quantum Dots Into Extracellular Matrix Gel as Carbon Monoxide Depot for Acoustically Triggered Time‐Programmable Anti‐Infective Therapy

Advanced Science, EarlyView.
A rigid‑flexible integrated CO depot is engineered by embedding rigid COFQDs into a flexible ECM gel network. The rigid framework enables high‑capacity CO storage and sonodynamic bacterial killing, while the flexible ECM gel controls sustained CO release, collectively eradicating multidrug‑resistant infection and promoting scarless healing.
Baohong Sun, Fang Han, Chunxiao Zhu, Zhiyuan Yang, Haoru Wang, Jinpei Mei, Jie Chen, Jingwen Zhu, Zihan Bo, Taju Wu, Xiaogang Zhou, Tao Ma, Yutian Su, Youhui Lin   +13 more
wiley   +1 more source

Analysing the interlinkage between diarrhoea and drinking water faecal contamination in India

Journal of Water and Health
Diarrhoea is one of the major waterborne diseases spread through the faecal–oral route causing over 10 million cases and over 1,000 deaths per year in India.
Gaurav Kapse, Satish Agnihotri, Pankaj Sekhsaria, Murali Sastry   +3 more
doaj   +1 more source

Crenotherapy using Spring Thermal Water in Western Algeria and its Effectiveness Against Kidney Stones

Scientific Journal of King Faisal University: Basic and Applied Sciences, 2023
Water is a natural resource with multiple uses. It is precious and important; therefore, it must meet the standard criteria. The goal of this project is to verify and estimate the physicochemical and bacteriological quality of water from the Dar Bentata ...
Afaf Amara-Rekkab
doaj   +1 more source

Genetic Ablation and Multi‐Omics Profiling Reveal CEP55 as a Key Driver of Tumorigenesis in Diverse Cancer Models

Advanced Science, EarlyView.
Genetic ablation of Cep55 in Pten‐deficient mouse models delays tumorigenesis. Integrated multi‐omics analyses (proteomics, phosphoproteomics, and spatial transcriptomics) reveal that CEP55 regulates oncogenic signaling (RAS/ERK, PI3K/AKT), integrin/FAK‐mediated adhesion, extracellular matrix (ECM) remodeling, and endocytosis.
Behnam Rashidieh, Yuanhao Yang, Amanda Louise Bain, Phillip Theron, Catharina Vosloo, Sahar Keshvari, Parinaz Ahangar, Brydie Bowden, Simon M. Tria, Ben B. Wang, Sandra Isenmann, Nicholas J. Westra van Holthe, Zherui Xiong, Hani Vu, Sowmya Sharma, Asmerom Sengal, J. Alejandro Lopez, John Finnie, Antonella Papa, Pascal H.G. Duijf, Quan Nguyen, Pirjo M. Apaja, Kum Kum Khanna   +22 more
wiley   +1 more source

The potency of native postbiotics and paraprobiotics in modulating inflammation by affecting the gut–kidney axis

Animal Models and Experimental Medicine, EarlyView.
Native postbiotics and paraprobiotics derived from Lactobacillus and Bifidobacterium strains were administered to dextran sulfate sodium–treated C57BL/6 mice to evaluate their impact on kidney inflammation via the gut–kidney axis. Histological analysis and quantitative polymerase chain reaction of autophagy‐related genes (atg5, atg7, atg12, atg13 ...
Fatemeh Haririzadeh Jouriani, Mahnaz Torfeh, Fatemeh Ashrafian, Niloofar Rezaie, Mohsen Mohammadi, Shadi Aghamohammad, Mahdi Rohani   +6 more
wiley   +1 more source

Water Quality Assessment of Selected Boreholes in Federal University Dutse Campus North-West, Nigeria

UMYU Journal of Microbiology Research, 2018
The present study was conducted to assess the physicochemical and bacteriological quality of water sampled from different boreholes on the campus of Federal University Dutse. Water samples were collected from six (6) different boreholes. Physicochemical
Amoo, A. O., Adeleye, A. O., Bate, G. B., Okunlola, I. A., Hambali, I. B.   +4 more
doaj   +1 more source