Results 61 to 70 of about 3,572 (201)

From Membrane Composition to Antimicrobial Strategies: Experimental and Computational Approaches to AMP Design and Selectivity

Small, Volume 22, Issue 16, 17 March 2026.
Antimicrobial peptides (AMPs) are promising candidates for next‐generation antibiotics, acting through mechanisms such as membrane disruption and intracellular targeting. This review examines how variations in bacterial membrane composition critically influence AMP activity.
Paolo Rossetti, Marius F.W. Trollmann, Christina Wichmann, Thomas Gutsmann, Christian Eggeling, Rainer A. Böckmann   +5 more
wiley   +1 more source

Pro-inflammatory agents released by pathogens, dying host cells, and neutrophils act synergistically to destroy host tissues: a working hypothesis

Journal of Inflammation Research, 2019
Isaac Ginsburg,1 Maya Korem,2 Erez Koren,3 James Varani4 1Institute of Dental Sciences, Faculty of Dental Medicine, The Hebrew University, Jerusalem, Israel; 2Department of Clinical Microbiology and Infectious Diseases, Hadassah-Hebrew University Medical
Ginsburg I, Korem M, Koren E, Varani J
doaj  

Functional Activity of Anti-Neisserial Surface Protein A Monoclonal Antibodies against Strains of Neisseria meningitidis Serogroup B

, 2001
Neisserial surface protein A (NspA) is currently being investigated with humans as a candidate vaccine for the prevention of meningococcal disease. Although NspA is highly conserved, the ability of anti-NspA antibodies to bind to or elicit complement ...
A. H. Lucas, G. R. Moe, P. Zuno-Mitchell, S. S. Lee, D. M. Granoff   +4 more
core   +1 more source

Beyond bacterial defences: the role of lysozyme in cancer

Clinical and Translational Medicine, Volume 16, Issue 2, February 2026.
Lysozyme (LYZ) is a multi‐functional secreted factor that encompasses both antibacterial and immunomodulatory functions. Emerging evidence highlights its complex role in tumour progression by directly influencing tumour cells and modulating the immune microenvironment.
Lei Wang, Qian Dong, Fuchu He, Zhiwen Gu, Aihua Sun   +4 more
wiley   +1 more source

The Kinetics of Bacteriolysis in the Gut of the Deposit Feeder Arenicola marina [PDF]

Applied and Environmental Microbiology, 1996
A turbidimetric technique was used to measure the bacteriolytic activities of digestive fluids collected seasonally from the deposit-feeding polychaete Arenicola marina. Lysis of cultured sedimentary bacteria was monitored spectrophotometrically.
C J, Plante, L M, Mayer, G M, King
openaire   +2 more sources

Human GBP1 binds LPS to initiate assembly of a caspase-4 activating platform on cytosolic bacteria [PDF]

, 2020
The human non-canonical inflammasome controls caspase-4 activation and gasdermin-D-dependent pyroptosis in response to cytosolic bacterial lipopolysaccharide (LPS).
Dilucca, M., Lim, Roderick Y H, Shkarina, Kateryna, Chen, Kaiwen W, José Carlos Santos, Kateryna Shkarina, Schneider, Larisa Kapinos, Lim, Roderick Y. H., Kaiwen W. Chen, Chen, K.W., Shkarina, K., Dave Boucher, Larisa Kapinos Schneider, Benjamin Demarco, Chen, Kaiwen W., Santos, J.C., Broz, Petr, Broz, P., Boucher, Dave, Dilucca, Marisa, Santos, José Carlos, Demarco, Benjamin, Schneider, L.K., Heilig, Rosalie, Rosalie Heilig, Demarco, B., Roderick Y. H. Lim, Boucher, D., Marisa Dilucca, Heilig, R., Lim, RYH, Petr Broz   +31 more
core   +1 more source

Dual‐function, Reusable, and Flexible Thermal Interface for Kinetic Monitoring of In Vitro Bioassays

Small Methods, Volume 10, Issue 3, 9 February 2026.
This work presents a reusable, dual‐function thermal interface for non‐contact, label‐free sensing and microwell‐independent temperature control in microplates within a single element. Real‐time monitoring of E. coli growth and the response to antibiotic treatment demonstrates the sensor's enhanced sensitivity in interface‐dominated processes compared ...
Daniel Nieder, Isli Cela, Željko Janićijević, Xinne Zhao, Larysa Baraban   +4 more
wiley   +1 more source

Therapeutic Potential of an Endolysin Derived from Kayvirus S25-3 for Staphylococcal Impetigo

Viruses, 2019
Impetigo is a contagious skin infection predominantly caused by Staphylococcus aureus. Decontamination of S. aureus from the skin is becoming more difficult because of the emergence of antibiotic-resistant strains.
Ichiro Imanishi, Jumpei Uchiyama, Toshihiro Tsukui, Junzo Hisatsune, Kaori Ide, Shigenobu Matsuzaki, Motoyuki Sugai, Koji Nishifuji   +7 more
doaj   +1 more source

Transgenic Tobacco Plants Expressing Synthetic Peptides: A Functional and Structural Analysis for Pathogen Resistance

Plant Biotechnology Journal, Volume 24, Issue 2, Page 526-546, February 2026.
Peptide Power: VR18 & KG18 Shield Tobacco from Bacterial Attack. A schematic shows how antimicrobial peptides VR18 and KG18 fight Pseudomonas syringae—bursting bacterial membranes and boosting disease resistance in transgenic tobacco, without harming plant health.
Karishma Biswas, Sudipta Mitra, Dibakar Roy, Sanhita Roy, Dibakar Sarkar, DeokHyun Son, Rohit Das, Anuradha Roy, Dulal Senapati, Humaira Ilyas, A. Harikishore, Ranjit Biswas, Suman Chakrabarty, DongKuk Lee, Indranil Biswas, Sudipto Saha, Pallob Kundu, Anirban Bhunia   +17 more
wiley   +1 more source

Monoclonal antibodies to meningococcal factor H binding protein with overlapping epitopes and discordant functional activity. [PDF]

PLoS ONE, 2012
Meningococcal factor H binding protein (fHbp) is a promising vaccine candidate. Anti-fHbp antibodies can bind to meningococci and elicit complement-mediated bactericidal activity directly.
Serena Giuntini, Peter T Beernink, Donald C Reason, Dan M Granoff   +3 more
doaj   +1 more source