Dietary muramidase leads to the downregulation of peptidoglycan biosynthesis and to caecal microbial modulation in laying hens [PDF]
Background In-feed muramidase enzyme has been linked to numerous advantages in several animal species. In the past years, muramidase has been shown to be effective in hydrolyzing peptidoglycan fragments, especially at small-intestine level in broilers ...
Salvatore Galgano, F Khattak
exaly +3 more sources
Dietary muramidase improved growth performance, feed efficiency, breast meat yield, and welfare of turkeys from hatch to market [PDF]
: Muramidase is an enzyme that hydrolyzes peptidoglycans of bacterial cell walls and improves performance of broilers in a dose-dependent manner. An experiment was conducted to evaluate muramidase supplementation, at a high or step-down dose, in turkeys ...
C L Walk
exaly +4 more sources
Optimizing Broiler Performance and Intestinal Morphology and Increasing Nutritional Availability via Microbial Muramidase Supplementation. [PDF]
An experiment was conducted in a commercial broiler farm to evaluate birds’ growth performance, intestinal morphology (IM), and total blood carotenoid levels when adding different inclusion rates of microbial muramidase (MUR) to broilers’ feed formula. A
Kadi AE +6 more
europepmc +2 more sources
Comparative effects of dietary muramidase and phytogenics on the growth performance and gastrointestinal functionality of broiler chickens. [PDF]
: The objective of the present study was to compare the effectiveness of dietary supplementation of muramidase (MUR) and 2 phytogenic additives on the growth performance, intestinal morphology, bacteria load, and production of short-chain fatty acids ...
Ceylan N +3 more
europepmc +2 more sources
Crystal Structure of Human Lysozyme Complexed with N-Acetyl-α-d-glucosamine
Human lysozyme is a natural non-specific immune protein that participates in the immune response of infants against bacterial and viral infections. Lysozyme is a well-known hydrolase that cleaves peptidoglycan in bacterial cell walls.
Ki Hyun Nam
doaj +1 more source
Orally administered β-glucan improves the hemolytic activity of the complement system in horses [PDF]
Background and Aim: Immune-modulating molecules mainly act on innate immune cells, which are central to early defense against invading pathogens and contribute to developing adaptive immunity. Yeast-extracted β-glucan, a model immune-modulating molecule,
Taline Scalco Picetti +7 more
doaj +1 more source
: The objective of the present study was to determine the effects of muramidase (MUR) supplemented to diets formulated with different fiber sources (inert or fermentable) on the growth performance and intestinal parameters of broiler chickens raised ...
Cristiano Bortoluzzi +8 more
doaj +1 more source
Safety and efficacy of a feed additive consisting of muramidase produced with Trichoderma reesei DSM 32338 (Balancius™) for laying hens (DSM nutritional products). [PDF]
Following a request from the European Commission, EFSA was asked to deliver a scientific opinion on the safety and efficacy of muramidase produced with Trichoderma reesei DSM 32338 (Balancius™) as a feed additive for laying hens.
EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) +23 more
europepmc +2 more sources
Fungal lysozyme leverages the gut microbiota to curb DSS-induced colitis
Colitis is characterized by colonic inflammation and impaired gut health. Both features aggravate obesity and insulin resistance. Host defense peptides (HDPs) are key regulators of gut homeostasis and generally malfunctioning in above-mentioned ...
Ida Søgaard Larsen +13 more
doaj +1 more source
Applications of Lysozyme, an Innate Immune Defense Factor, as an Alternative Antibiotic
Lysozyme is a ~14 kDa protein present in many mucosal secretions (tears, saliva, and mucus) and tissues of animals and plants, and plays an important role in the innate immunity, providing protection against bacteria, viruses, and fungi.
Patrizia Ferraboschi +2 more
doaj +1 more source

