Resistance to mucosal lysozyme compensates for the fitness deficit of peptidoglycan modifications by Streptococcus pneumoniae. [PDF]
PLoS Pathogens, 2008 The abundance of lysozyme on mucosal surfaces suggests that successful colonizers must be able to evade its antimicrobial effects. Lysozyme has a muramidase activity that hydrolyzes bacterial peptidoglycan and a non-muramidase activity attributable to ...
Kimberly M Davis +3 more
doaj +1 more source
Retraction: Interaction of fibrinogen and muramidase-released protein promotes the development of <i>Streptococcus suis</i> meningitis. [PDF]
Front MicrobiolFrontiers Editorial Office.
europepmc +2 more sources
EFSA Journal, 2021 Following a request from the European Commission, the Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) was asked to deliver a scientific opinion on the safety and efficacy of muramidase produced by Trichoderma reesei DSM 32338 ...
EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) +27 more
doaj +1 more source
Poultry Science, 2023 : The objective of these studies was to evaluate the impact of dietary muramidase (MUR) on endogenous amino acids (AA) losses and digestibility of nutrients in wheat and corn-based broiler diets.
E. Pérez-Calvo +3 more
doaj +1 more source
Dietary eubiotics of microbial muramidase and glycan improve intestinal villi, ileum microbiota composition and production trait of broiler. [PDF]
J Anim Sci BiotechnolBackground Optimal gut health is important to maximize growth performance and feed efficiency in broiler chickens. A total of 1,365 one-day-old male Ross 308 broiler chickens were randomly divided into 5 treatments groups with 21 replicates, 13 birds per
Cho S +4 more
europepmc +2 more sources
Mechanisms of substrate recognition by a typhoid toxin secretion-associated muramidase
eLife, 2020 Typhoid toxin is a virulence factor for the bacterial pathogen Salmonella Typhi, which causes typhoid fever in humans. After its synthesis by intracellular bacteria, typhoid toxin is secreted into the lumen of the Salmonella-containing vacuole by a ...
Tobias Geiger +3 more
doaj +1 more source
A microbial muramidase improves growth performance and reduces inflammatory cell infiltration in the intestine of broilers chickens under Eimeria and Clostridium perfringens challenge. [PDF]
Poult Sci: The objective of the present studies was to evaluate muramidase (MUR) supplementation in broilers under Eimeria and/or Clostridium perfringens challenge. For this, 2 experiments were conducted. Experiment 1.
Bortoluzzi C +7 more
europepmc +2 more sources
Rearing system, utility type and hens’ age as a factor modifying lysozyme's hydrolytic activity [PDF]
Roczniki Naukowe Polskiego Towarzystwa Zootechnicznego, 2021 The aim of study was to analyze the impact of the utility type, age and rearing system of hens on egg quality traits and the enzymatic activity of egg albumen lysozyme (LA). The material consisted of 120 eggs from two genotypes of hens: Hy-Line Brown and
Karolina Wengerska +4 more
doaj +1 more source
Scientific Reports, 2022 A novel dietary muramidase has been shown to have positive effects on broiler chickens. However, very little is known about its mechanisms of action. The present multi-omics investigation sought to address this knowledge gap.
Giorgio Brugaletta +9 more
doaj +1 more source
Molecular basis of resistance to muramidase and cationic antimicrobial peptide activity of lysozyme in staphylococci. [PDF]
PLoS Pathogens, 2007 It has been shown recently that modification of peptidoglycan by O-acetylation renders pathogenic staphylococci resistant to the muramidase activity of lysozyme. Here, we show that a Staphylococcus aureus double mutant defective in O-acetyltransferase A (
Silvia Herbert +8 more
doaj +1 more source