International Wound Journal, Volume 22, Issue 11, November 2025.ABSTRACT The article describes the outcomes of a single‐centre investigation on the use of OZOILE to improve the healing process in patients with chronic diabetic ulcers. This is a non‐randomised interventional study which aims to assess the differences between two groups (total 200 patients) by evaluating healing time at 15, 30, 45, 60, 75 and 90 days.
Barbara De Angelis +12 more
wiley +1 more source
New proteoliposome vaccine formulation from N. meningitidis serogroup B, without aluminum hydroxide, retains its antimeningococcal protectogenic potential as well as Th-1 adjuvant capacity [PDF]
, 2013 Proteoliposomes purified from the Outer Membrane of Neisseria meningitidis B, have been successfully used as core for adjuvants and vaccine formulations.
Cedré, Bárbara +5 more
core +2 more sources
Current status and future perspectives of multi‐modal bacteria‐based cancer therapies
Clinical and Translational Medicine, Volume 15, Issue 10, October 2025.Bacteria exhibit inherent tumour‐targeting capabilities, particularly thriving in hypoxic tumour microenvironments (TMEs) and activating potent anti‐tumour immune responses through pathogen‐associated molecular patterns (PAMPs) and immunomodulation.
Shuai Fan +9 more
wiley +1 more source
Development of an automated, high-throughput bactericidal assay that measures cellular respiration as a survival readout for Neisseria meningitidis [PDF]
, 2011 Complement-mediated bactericidal activity has long been regarded as the serological correlate of protective immunity against Neisseria meningitidis. This was affirmed in 2005 at a WHO-sponsored meningococcal serology standardization workshop.
Mak, Puiying A. +10 more
core +1 more source
Antibody-Mediated Bacteriolysis: Enhanced Killing of Cyclacillin-Treated Bacteria
Experimental Biology and Medicine, 1976 SummaryIncubation of Escherichia coli with sublethal concentrations of the semisynthetic penicillins cyclacillin and ampicil-lin substantially increased the susceptibility of the bacteria to subsequent lysis by serum antibody or specifically immunized murine spleen cells in the presence of guinea pig complement.
H, Friedman, G H, Warren
openaire +2 more sources
Tracing the evolutionary pathway: on the origin of mitochondria and eukaryogenesis
The FEBS Journal, Volume 292, Issue 19, Page 5026-5041, October 2025.This study examines the stepwise transition from archaeal–bacterial associations to the emergence of eukaryotic cells. Metabolic cooperation and endosymbiosis fostered ecological and genetic integration, with extensive gene transfer reshaping host biology.
J. Ernesto Bravo‐Arévalo
wiley +1 more source
Requirement of endogenous tumor necrosis factor/cachectin for recovery from experimental peritonitis [PDF]
, 1990 By intrasplenic immunization we raised a rat mAb (mAb V1q; IgG2a, kappa) with a potent neutralizing activity against natural mouse TNF (1 microgram/ml mAb V1q/100 U/ml TNF). mAb V1q was used to study the role of endogenous TNF in experimental peritonitis
Echtenacher, B. +3 more
core
Component release and mechanical properties of endodontic sealers following incorporation of antimicrobial agents [PDF]
, 2017 Root canal sealers with antimicrobial activity are highly beneficial; therefore, their antimicrobial properties could be improved by incorporation of antimicrobial agents.
Booth, Samantha +5 more
core +2 more sources
The Neglected Role of GSDMD C‐Terminal in Counteracting Type I Interferon Signaling
Advanced Science, Volume 12, Issue 33, September 4, 2025.The C‐terminal domain of Gasdermin D (GSDMD‐CT) shows functions beyond pyroptosis. GSDMD‐CT negatively regulates IFN‐I signaling during viral infection by triggering autophagic degradation of RIG‐I and TBK1. GSDMD‐CT interacts with retinoic acid‐inducible gene‐I (RIG‐I) and tank‐binding kinase 1 (TBK1), leading to TRIM28‐mediated ubiquitination and ...
Weilv Xu +17 more
wiley +1 more source
Guanylate-binding Protein 1 (GBP1) contributes to the immunity of human mesenchymal stromal cells against toxoplasma gondii [PDF]
, 2017 Mesenchymal stromal cells (MSCs) have recently been shown to play important roles in mammalian host defenses against intracellular pathogens, but the molecular mechanism still needs to be clarified.
Aiping Qin +19 more
core +1 more source