Ankyrin-mediated self-protection during cell invasion by the bacterial predator Bdellovibrio bacteriovorus [PDF]
Predatory Bdellovibrio bacteriovorus are natural antimicrobial organisms, killing other bacteria by whole-cell invasion. Self-protection against prey-metabolizing enzymes is important for the evolution of predation.
AA Russo +36 more
core +4 more sources
Current status and future perspectives of multi‐modal bacteria‐based cancer therapies
Bacteria exhibit inherent tumour‐targeting capabilities, particularly thriving in hypoxic tumour microenvironments (TMEs) and activating potent anti‐tumour immune responses through pathogen‐associated molecular patterns (PAMPs) and immunomodulation.
Shuai Fan +9 more
wiley +1 more source
Monoclonal antibodies to meningococcal factor H binding protein with overlapping epitopes and discordant functional activity. [PDF]
Meningococcal factor H binding protein (fHbp) is a promising vaccine candidate. Anti-fHbp antibodies can bind to meningococci and elicit complement-mediated bactericidal activity directly.
Serena Giuntini +3 more
doaj +1 more source
Characterization and genome sequencing of a Citrobacter freundii phage CfP1 harboring a lysin active against multidrug-resistant isolates [PDF]
Citrobacter spp., although frequently ignored, is emerging as an important nosocomial bacterium able to cause various superficial and systemic life-threatening infections.
AE Darling +59 more
core +3 more sources
Tracing the evolutionary pathway: on the origin of mitochondria and eukaryogenesis
This study examines the stepwise transition from archaeal–bacterial associations to the emergence of eukaryotic cells. Metabolic cooperation and endosymbiosis fostered ecological and genetic integration, with extensive gene transfer reshaping host biology.
J. Ernesto Bravo‐Arévalo
wiley +1 more source
Excessive use of antimicrobials and inadequate infection control practices has turned antimicrobial resistance (AMR) into a global, public health peril. We studied the expression of qnrA, qnrB, and qnrS plasmid in ciprofloxacin (CIP)-resistant strains of
Alexandru O. Doma +10 more
doaj +1 more source
Antibody-Mediated Bacteriolysis: Enhanced Killing of Cyclacillin-Treated Bacteria
SummaryIncubation of Escherichia coli with sublethal concentrations of the semisynthetic penicillins cyclacillin and ampicil-lin substantially increased the susceptibility of the bacteria to subsequent lysis by serum antibody or specifically immunized murine spleen cells in the presence of guinea pig complement.
H, Friedman, G H, Warren
openaire +2 more sources
The Neglected Role of GSDMD C‐Terminal in Counteracting Type I Interferon Signaling
The C‐terminal domain of Gasdermin D (GSDMD‐CT) shows functions beyond pyroptosis. GSDMD‐CT negatively regulates IFN‐I signaling during viral infection by triggering autophagic degradation of RIG‐I and TBK1. GSDMD‐CT interacts with retinoic acid‐inducible gene‐I (RIG‐I) and tank‐binding kinase 1 (TBK1), leading to TRIM28‐mediated ubiquitination and ...
Weilv Xu +17 more
wiley +1 more source
Seasonal Depth-Related Gradients in Virioplankton: Lytic Activity and Comparison with Protistan Grazing Potential in Lake Pavin (France) [PDF]
International audienceThis study presents an original depth-related survey of virioplankton lytic activity in relation to prokaryotic production and potential protistan bacterivory in the deep (Zmax092 m) meromictic volcanic Lake Pavin (Massif Central ...
Colombet, Jonathan +1 more
core +1 more source
Immunology in clinic review series; focus on autoinflammatory diseases: role of inflammasomes in autoinflammatory syndromes [PDF]
Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/90366/1/j.1365-2249.2011.04535.x ...
Franchi, Luigi, Ozkurede, V. U.
core +1 more source

