Host physiology-dependent lysis timing shapes bacteriophage competition under nutrient fluctuations [PDF]
mSystemsWhen bacteriophages infect starved host bacteria, the restrictive host physiology may lead to prolonged latent periods and/or reduced burst sizes, compared to infection of a fast-growing bacterium.
Anja K. Ehrmann, Namiko Mitarai
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Isolation of GAL Tularemia Bacteriophage and its Characteristics
Проблемы особо опасных инфекций, 2008 Temperate tularemia bacteriophage was for the first time isolated from the organs of guinea-pig infected with live tularemia vaccine strain N 15 of RIEH line.
A. A. Grigor’ev +9 more
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Overexpression of AmpC Promotes Bacteriophage Lysis of Ampicillin-Resistant Escherichia coli [PDF]
Frontiers in Microbiology, 2020 Infections caused by antibiotic-resistant Escherichia coli are a threat to human and animal health globally. Phage therapy has made great progress for the treatment of drug-resistant infections, but it is still unclear whether E.
Shuang Wang +16 more
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Engineering a T7 bacteriophage to attenuate LPS-driven inflammatory responses during bacteriolysis [PDF]
Applied and Environmental MicrobiologyBacterial lysis during treatment of Gram-negative infections can release lipopolysaccharide (LPS) and aggravate inflammation. Here, we engineered two complementary T7 bacteriophages: T7-nluc, a NanoLuc reporter bacteriophage for real-time monitoring of ...
Tong Yu +8 more
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A common, non-optimal phenotypic endpoint in experimental adaptations of bacteriophage lysis time [PDF]
BMC Evolutionary Biology, 2012 Background Optimality models of evolution, which ignore genetic details and focus on natural selection, are widely used but sometimes criticized as oversimplifications.
Chantranupong Lynne, Heineman Richard H
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Live and let die: Lysis time variability and resource limitation shape lytic bacteriophage fitness. [PDF]
PLoS Computational BiologyBacteriophages (phages) play a critical role in controlling bacterial populations, both in nature and as potential therapeutic agents. Their ability to replicate, compete against each other, and eradicate target cell populations is usually understood ...
Aaron Smith +3 more
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F‐Type Pyocin Versus Phage λ Tail: Conserved Hub, Divergent Fibers [PDF]
Advanced Science, Volume 13, Issue 61, 3 November 2026.Near‐atomic cryo‐EM structures of a Gram‐negative F‐type pyocin reveal a conserved tail tip architecture shared with bacteriophage λ together with a previously unrecognized side‐fiber attachment mode. These findings provide new insight into tailocin assembly and host recognition and establish a structural framework for engineering precision ...
Zhiwei Gu +5 more
wiley +2 more sources
Structural Receptors and Host Adaptations Affecting the Bacteriophage Targeting of Vibrio Pathogens [PDF]
MicroorganismsThe widespread exposure of multidrug-resistant bacterial strains due to excessive use of antibiotics has accelerated the bacteriophage applications as highly specific antibacterial agents competent to target resistant pathogenic Vibrio through receptor ...
Muqadas Altaf +7 more
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Restoration of O-antigen production in E. coli K-12 DFB1655 confers resistance to T2 bacteriophage-mediated lysis [PDF]
, 2022 Bacteriophage infection of Escherichia coli has long been studied to understand possible applications to bacterial disease, due to the specificity and efficiency of lysis. Commonly used strains such as E.
Shen, Jessica +3 more
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Characterizing RecA-Independent Induction of Shiga toxin2-encoding Phages by EDTA Treatment [PDF]
, 2012 The bacteriophage life cycle has an important role in Shiga toxin (Stx) expression. The induction of Shiga toxin-encoding phages (Stx phages) increases toxin production as a result of replication of the phage genome, and phage lysis of the host cell also
Muniesa Maite +8 more
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