Rapid bacteriolysis of Staphylococcus aureus by lysin exebacase [PDF]
Microbiology Spectrum, 2023 Lysins (peptidoglycan hydrolases) are promising new protein-based antimicrobial candidates under development to address rising antibiotic resistance encountered among pathogenic bacteria.
Steven M Swift, Raymond Schuch
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Intracellular bacteriolysis contributes to pathogenicity of Staphylococcus aureus by exacerbating AIM2-mediated inflammation and necroptosis [PDF]
Virulence, 2022 Staphylococcus aureus can survive within phagocytes. Indeed, we confirm in this study that approximately 10% of population persists in macrophages during S.
Yong-Jun Yang, Jinfeng Miao
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Bacteriolysis – a mere laboratory curiosity?
Critical Reviews in Microbiology, 2018 The role of bacteriolysis in the pathophysiology of microbial infections dates back to 1893 when Buchner and Pfeiffer reported for the first time the lysis of bacteria by immune serum and related this phenomenon to the immune response. Later on, basic anti-microbial peptides and certain beta-lactam antibiotics have been shown not only to kill ...
Isaac Ginsburg, Erez Koren
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Enhancement of bacteriolysis of Shuffled phage PhiX174 gene E [PDF]
Virology Journal, 2011 Bacterial ghosts that are generated using the regulated PhiX174 lysis gene E offer a new avenue for the study of inactivated vaccines. Here, we constructed a library of mutant gene E using a gene-shuffling technique.
Wang Chun-lai +9 more
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Engineering a T7 bacteriophage to attenuate LPS-driven inflammatory responses during bacteriolysis [PDF]
Applied and Environmental MicrobiologyBacterial lysis during treatment of Gram-negative infections can release lipopolysaccharide (LPS) and aggravate inflammation. Here, we engineered two complementary T7 bacteriophages: T7-nluc, a NanoLuc reporter bacteriophage for real-time monitoring of ...
Tong Yu +8 more
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A switch in surface polymer biogenesis triggers growth-phase-dependent and antibiotic-induced bacteriolysis [PDF]
eLife, 2019 Penicillin and related antibiotics disrupt cell wall synthesis to induce bacteriolysis. Lysis in response to these drugs requires the activity of cell wall hydrolases called autolysins, but how penicillins misactivate these deadly enzymes has long ...
Josué Flores-Kim +4 more
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THE RELATION OF BACTERIOLYSIS TO PROTEOLYSIS [PDF]
Journal of Experimental Medicine, 1914 1. There is no demonstrable increase in non-coagulable nitrogen during bacteriolysis. 2. Bacteria treated with immune serum and complement are so altered that they are more readily digested by trypsin. 3. Bacteria treated with complement alone become more resistant to proteolysis. 4. Bacteria treated with an
James W Jobling +2 more
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Perforin enhances the granulysin-induced lysis of Listeria innocua in human dendritic cells [PDF]
BMC Immunology, 2007 Background Cytotoxic T lymphocytes (CTL) and natural killer (NK) cells play an essential role in the host defence against intracellular pathogens such as Listeria, and Mycobacteria.
Wagner Carsten A +7 more
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Note on the bacteriolysis of gelatin [PDF]
The Analyst, 1897 n ...
Rideal, S., Orchard, R.
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A Novel Antimicrobial Metabolite Produced by Paenibacillus apiarius Isolated from Brackish Water of Lake Balkhash in Kazakhstan [PDF]
Microorganisms, 2022 Four aerobic bacteria with bacteriolytic capabilities were isolated from the brackish water site Strait Uzynaral of Lake Balkhash in Kazakhstan. The morphology and physiology of the bacterial isolates have subsequently been analyzed.
Alexander Meene +8 more
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