Synergistic Antibacterial Effect of Ethyl Acetate Fraction of Vernonia amygdalina Delile Leaves with Tetracycline against Clinical Isolate Methicillin-Resistant Staphylococcus aureus (MRSA) and Pseudomonas aeruginosa [PDF]
Advances in Pharmacological and Pharmaceutical Sciences, 2023 Multidrug-resistant bacteria have raised global concern about the inability to fight deadly infectious diseases. Methicillin-resistant Staphylococcus aureus (MRSA) and Pseudomonas aeruginosa are the most common resistant bacteria that are causing ...
Denny Satria +5 more
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Borrelia valaisiana resist complement-mediated killing independently of the recruitment of immune regulators and inactivation of complement components. [PDF]
PLoS ONE, 2013 Spirochetes belonging to the Borrelia (B.) burgdorferi sensu lato complex differ in their resistance to complement-mediated killing, particularly in regard to human serum.
Jasmin Schwab +7 more
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Structural insights into Cir-mediated killing by the antimicrobial protein Microcin V [PDF]
Communications BiologyDrug-resistant bacteria are a global concern. Novel treatments are needed, but are difficult to develop for Gram-negative species due to the need to traverse the outer membrane to reach targets beneath.
Stavros A. Maurakis +5 more
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Bacteriolysis is inhibited by hydrogen peroxide and by proteases [PDF]
Agents and Actions, 1989 Treatment of Staphylococcus aureus in vitro with cationic agents results in the activation of their autolytic wall enzymes and in the degradation of their cell walls. Exposure of staphylococci either to hydrogen peroxide or the proteinases abolished the autolytic process.
Ginsburg, Isaac
openaire +4 more sources
In Silico Design and Characterization of the Essential Outer-Membrane Lipoprotein LolB-Derived Multi-Epitope Vaccine Candidate Against Pseudomonas aeruginosa [PDF]
Methods and ProtocolsPseudomonas aeruginosa causes severe healthcare-associated infections, yet no vaccine has been licenced. To circumvent the antigenic variability of classical surface antigens, we evaluated LolB—an essential outer-membrane lipoprotein whose periplasmic ...
Sinethemba H. Yakobi +1 more
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The non-nutritive sweetener rebaudioside a enhances phage infectivity [PDF]
Scientific ReportsNon-nutritive sweeteners (NNS) are widely employed in foodstuffs. However, it has become increasingly evident that their consumption is associated with bacterial dysbiosis, which, in turn, is linked to several health conditions, including a higher risk ...
Luigi Marongiu +6 more
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Discovery of a family of menaquinone-targeting cyclic lipodepsipeptides for multidrug-resistant Gram-positive pathogens [PDF]
Communications BiologyMenaquinone (MK) in bacterial membrane is an attractive target for the development of novel therapeutic agents. Mining the untapped chemical diversity encoded by Gram-negative bacteria presents an opportunity to identify additional MK-binding antibiotics
Runze Sun +6 more
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Identification and Characterization of a Novel Prophage Lysin against Streptococcus dysgalactiae [PDF]
MoleculesStreptococcus dysgalactiae infection can cause bovine mastitis and lead to huge economic losses for the dairy industry. The abuse of antibiotics has resulted in growing drug resistance of S.
Linan Xu +7 more
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Phage cocktail amikacin combination as a potential therapy for bacteremia associated with carbapenemase producing colistin resistant Klebsiella pneumoniae [PDF]
Scientific ReportsThe increasing occurrence of hospital-associated infections, particularly bacteremia, caused by extensively drug-resistant (XDR) carbapenemase-producing colistin-resistant Klebsiella pneumoniae highlights a critical requirement to discover new ...
Aye Mya Sithu Shein +38 more
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SNAKE VENOM IN RELATION TO HÆMOLYSIS, BACTERIOLYSIS, AND TOXICITY [PDF]
Journal of Experimental Medicine, 1902 S Flexner, Noguchi Hideyo
exaly +3 more sources