In Silico Design and Characterization of the Essential Outer-Membrane Lipoprotein LolB-Derived Multi-Epitope Vaccine Candidate Against Pseudomonas aeruginosa [PDF]
Pseudomonas aeruginosa causes severe healthcare-associated infections, yet no vaccine has been licenced. To circumvent the antigenic variability of classical surface antigens, we evaluated LolB—an essential outer-membrane lipoprotein whose periplasmic ...
Sinethemba H. Yakobi +1 more
doaj +2 more sources
The non-nutritive sweetener rebaudioside a enhances phage infectivity [PDF]
Non-nutritive sweeteners (NNS) are widely employed in foodstuffs. However, it has become increasingly evident that their consumption is associated with bacterial dysbiosis, which, in turn, is linked to several health conditions, including a higher risk ...
Luigi Marongiu +6 more
doaj +2 more sources
Discovery of a family of menaquinone-targeting cyclic lipodepsipeptides for multidrug-resistant Gram-positive pathogens [PDF]
Menaquinone (MK) in bacterial membrane is an attractive target for the development of novel therapeutic agents. Mining the untapped chemical diversity encoded by Gram-negative bacteria presents an opportunity to identify additional MK-binding antibiotics
Runze Sun +6 more
doaj +2 more sources
Identification and Characterization of a Novel Prophage Lysin against Streptococcus dysgalactiae [PDF]
Streptococcus dysgalactiae infection can cause bovine mastitis and lead to huge economic losses for the dairy industry. The abuse of antibiotics has resulted in growing drug resistance of S.
Linan Xu +7 more
doaj +2 more sources
Phage cocktail amikacin combination as a potential therapy for bacteremia associated with carbapenemase producing colistin resistant Klebsiella pneumoniae [PDF]
The increasing occurrence of hospital-associated infections, particularly bacteremia, caused by extensively drug-resistant (XDR) carbapenemase-producing colistin-resistant Klebsiella pneumoniae highlights a critical requirement to discover new ...
Aye Mya Sithu Shein +38 more
doaj +2 more sources
SNAKE VENOM IN RELATION TO HÆMOLYSIS, BACTERIOLYSIS, AND TOXICITY [PDF]
S Flexner, Noguchi Hideyo
exaly +3 more sources
SURGICAL AND NON-SURGICAL LASER PREPROSTHETIC PERIODONTAL PREPARATION. LOW-LEVEL LASER THERAPY AND PHOTOACTIVATED DISINFECTION [PDF]
Background: Clinical success and functional durability of indirect restorations depend on optimal dental health before the prosthetic treatment and the manipulation of the gingival tissues.
Rada Kazakova
doaj +1 more source
Bacteriolysis by a Species of Streptomyces [PDF]
SUMMARY: The lysis of dead Bacterium coli by concentrates prepared from filtrates of a Streptomyces sp. is probably due to proteolysis. In any event the lysis can be accounted for by proteolysis, even if the action of other bacteriolytic enzymes cannot be excluded.
T Y, TAI, W E, van HEYNINGEN
openaire +2 more sources
Dual Inhibitory Activity of Petroselinic Acid Enriched in Fennel Against Porphyromonas gingivalis
Increasing evidence has shown that a major periodontal pathobiont, Porphyromonas gingivalis, triggers oral dysbiosis leading to deterioration not only of periodontal health, but also of several systemic conditions.
Nanami Yoshino +3 more
doaj +1 more source
Antibiotic tolerance characterized by slow killing of bacteria in response to a drug can lead to treatment failure and promote the emergence of resistance.
Taiyeb Zahir +15 more
doaj +1 more source

