Results 31 to 40 of about 3,337 (166)

A Single-Domain Antibody Targeting Complement Component C5 Acts as a Selective Inhibitor of the Terminal Pathway of the Complement System and Thus Functionally Mimicks the C-Terminal Domain of the Staphylococcus aureus SSL7 Protein

open access: yesFrontiers in Immunology, 2018
The complement system is an efficient anti-microbial effector mechanism. On the other hand abnormal complement activation is involved in the pathogenesis of multiple inflammatory and hemolytic diseases.
Laure Yatime   +10 more
doaj   +1 more source

Human complement regulators C4b-binding protein and C1 esterase inhibitor interact with a novel outer surface protein of Borrelia recurrentis. [PDF]

open access: yesPLoS Neglected Tropical Diseases, 2010
The spirochete Borrelia recurrentis is the causal agent of louse-borne relapsing fever and is transmitted to humans by the infected body louse Pediculus humanus. We have recently demonstrated that the B.
Sonja Grosskinsky   +5 more
doaj   +1 more source

100th Anniversary of Jules Bordet's Nobel Prize: Tribute to a Founding Father of Immunology

open access: yesFrontiers in Immunology, 2019
The 100th Anniversary of the Nobel Prize in Physiology or Medicine 1919 awarded to Jules Bordet offers the opportunity to underline the contributions of this Belgian doctor to the blooming of immunology at the end of the nineteenth century at the ...
Jean-Marc Cavaillon   +3 more
doaj   +1 more source

Perforin enhances the granulysin-induced lysis of Listeria innocua in human dendritic cells

open access: yesBMC Immunology, 2007
Background Cytotoxic T lymphocytes (CTL) and natural killer (NK) cells play an essential role in the host defence against intracellular pathogens such as Listeria, and Mycobacteria.
Wagner Carsten A   +7 more
doaj   +1 more source

Antibacterial Indole Diketopiperazine Alkaloids from the Deep-Sea Cold Seep-Derived Fungus Aspergillus chevalieri

open access: yesMarine Drugs, 2023
A large body of fungal secondary metabolites has been discovered to exhibit potent antibacterial activities with distinctive mechanisms and has the potential to be an untapped resource for drug discovery.
Li-Hong Yan   +5 more
doaj   +1 more source

Comparative effect of different pathogens on the condition of dysbiosis in rat kidneys

open access: yesJournal of Education, Health and Sport, 2020
Aim. Compare the effect of different pathogens on the development of kidney dysbiosis.Methods. The pathogens used were hydrazine sulfate, prednisolone, cyclophosphamide, lincomycin, and lipopolysaccharide (LPS).
A. P. Levitsky   +5 more
doaj   +1 more source

Optimization of Oligosaccharide Preparation Process and Physiological Activity Analysis of Konjac Crude Powder

open access: yesShipin gongye ke-ji, 2023
In this paper, konjac powde were hydrolyzed by Bacillus licheniformis to prepare oligosaccharides. The effects of concentration of konjac powder, inoculum amount of strain, bacteriolysis temperature and hydrolysis time on hydrolysis rate of konjac powder
Wei ZHANG   +6 more
doaj   +1 more source

The Primary Mode of Action of Lippia graveolens Essential Oil on Salmonella enterica subsp. Enterica Serovar Typhimurium

open access: yesMicroorganisms, 2023
Essential oils are known to exhibit diverse antimicrobial properties, showing their value as a natural resource. Our work aimed to investigate the primary mode of action of Cuban Lippia graveolens (Kunth) essential oil (EO) against Salmonella enterica ...
Annie Rubio Ortega   +9 more
doaj   +1 more source

A switch in surface polymer biogenesis triggers growth-phase-dependent and antibiotic-induced bacteriolysis

open access: yeseLife, 2019
Penicillin and related antibiotics disrupt cell wall synthesis to induce bacteriolysis. Lysis in response to these drugs requires the activity of cell wall hydrolases called autolysins, but how penicillins misactivate these deadly enzymes has long ...
Josué Flores-Kim   +4 more
doaj   +1 more source

Protection Against Invasive Infections in Children Caused by Encapsulated Bacteria

open access: yesFrontiers in Immunology, 2018
The encapsulated bacteria Streptococcus pneumoniae, Neisseria meningitis, Haemophilus influenzae, and Streptococcus agalactiae (Group B Streptococcus) have been responsible for the majority of severe infections in children for decades, specifically ...
Manish Sadarangani, Manish Sadarangani
doaj   +1 more source

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