Results 241 to 250 of about 44,922 (302)

Personalized bacteriophage therapy outcomes for 100 consecutive cases: a multicentre, multinational, retrospective observational study. [PDF]

open access: yesNat Microbiol
Pirnay JP   +27 more
europepmc   +1 more source

KP bacteriophage therapy studies in mouse infection models.

open access: gold
Julie Le Bris (17301532)   +4 more
openalex   +1 more source

Bacterial Expression of Gene‐Encoding DNA Origami Structures

open access: yesSmall Structures, Volume 7, Issue 2, February 2026.
Bacterial targeting via programmable DNA origami, varying in rigidity and compactness is unexplored. In transformation assays, origami reduces transformation efficiency compared to single‐stranded scaffolds. Structural features and surface modifications, however, improve transformation outcomes.
Verena Dobretzberger   +7 more
wiley   +1 more source

Crystal structure of Schistosoma mansoni cathepsin D1 in complex with a nanobody reveals the conformation of the propeptide‐bound state

open access: yesActa Crystallographica Section D, Volume 82, Issue 2, Page 140-150, February 2026.
Structural characterization of S. mansoni cathepsin D1 in complex with a nanobody reveals the conformation of the propeptide‐bound state and identifies a schistosome‐specific epitope.Schistosoma mansoni cathepsin D1 (SmCD1) has been shown to be an essential enzyme for helminth metabolism due to its role in haemoglobin degradation: a key amino‐acid ...
Kelly L. Parker   +7 more
wiley   +1 more source

The Role of the Gut Microbiome in the Complex Network of Frailty Syndrome and Associated Comorbidities in Aging

open access: yesAging Cell, Volume 25, Issue 2, February 2026.
This study analyzed gut microbiota in older adults with and without Frailty Syndrome by 16S rRNA gene sequencing and metagenomics. Frailty was associated with altered microbial composition, metabolic functions, and increased antimicrobial resistance, whereas non‐frail individuals showed healthier profiles.
Ana Barberá   +5 more
wiley   +1 more source

Model-Informed Development of Bacteriophage Therapy: Bridging In Vitro and In Vivo Efficacy Against Multidrug-resistant Pseudomonas aeruginosa. Jun Seok Cha et al.

open access: green
Cha, Jun Seok   +9 more
openalex   +1 more source

B‐Cell Repertoire of Children With Atopic Dermatitis Exhibits Altered IgE Maturation Associated With Allergic Food Sensitization

open access: yesAllergy, Volume 81, Issue 2, Page 513-523, February 2026.
IgH repertoire sequencing of a large atopic dermatitis cohort reveal reduced IgE somatic hypermutation and increased IgE diversity associated with food allergen sensitization. Presence of a dog during the first year of life is associated with increased IgE somatic hypermutation, possibly countering the effect of food sensitization.
Kirandeep K. Gill   +18 more
wiley   +1 more source

Parental Consent to a Neonatal Clinical Study: The Roles of Uncertainty, Burden of Sample Collection and Societal Expectations

open access: yesActa Paediatrica, Volume 115, Issue 2, Page 353-359, February 2026.
ABSTRACT Aim Recruiting participants for neonatal clinical studies may be challenging because parental consent is required shortly after birth. This study aimed to explore reasons for parental decline of participation in a neonatal study. Method This qualitative sub‐study was conducted in the Capital Region of Denmark between June 2022 and April 2023 ...
Susanne Soendergaard Kappel   +5 more
wiley   +1 more source

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