Results 221 to 230 of about 48,920 (278)

Overcoming <i>Pseudomonas aeruginosa</i> in Chronic Suppurative Lung Disease: Prevalence, Treatment Challenges, and the Promise of Bacteriophage Therapy. [PDF]

Antibiotics (Basel)
Singh J, Solomon M, Iredell J, Selvadurai H.   +3 more
europepmc   +1 more source

Chemical‐Assembled Macrophage‐Engaging Glypican‐3 × Signal Regulatory Protein‐α (SIRP‐α) Bispecific Antibody for Immunotherapy Against Liver Cancer

MedComm, Volume 7, Issue 7, July 2026.
We developed a novel chemical strategy to generate a glypican‐3 × SIRP‐α bispecific antibody that simultaneously blocks the CD47 “don't eat me” signal, engages macrophages to target liver cancer cells for enhanced phagocytosis, and antigen presentation. This novel combination of targets demonstrates remarkable efficacy in vitro and in vivo.
Bo Tang, Wing Hei Leung, Chihao Shao, Dongfang Li, Kwai Man Lau, Macro K. H. Lui, Jingyi Liu, Jacky C. H. Chu, Clare S. W. Yan, Chi‐Ming Che, Xuechen Li, Wing‐Tak Wong, Larry Ming Cheung Chow, Terence K. W. Lee, Clarence T. T. Wong   +14 more
wiley   +1 more source

Model-informed development of bacteriophage therapy: bridging <i>in vitro</i> and <i>in vivo</i> efficacy against multidrug-resistant <i>Pseudomonas aeruginosa</i>. [PDF]

mSystems
Cha JS, Kim K, You HJ, Kim D, Park HH, Heo S, Kim CO, Jin BH, Yong D, Chae D.   +9 more
europepmc   +1 more source

Intratumoral Microbiota in Tumor: Current Understandings and Future Perspectives

MedComm, Volume 7, Issue 7, July 2026.
Intratumoral bacteria are emerging as active regulators of cancer evolution rather than bystanders. This review outlines how tumor‐resident microbes drive tumor initiation and growth by inducing genomic instability, epigenetic reprogramming, oncogenic signaling, and chronic inflammation, while promoting metastatic spread via invasion, angiogenesis ...
Jiawei Chen, Yupan Bai, Lu Shen, Jiacheng Ying, Jie Xu, Jiayin Tang, Yujie Bao   +6 more
wiley   +1 more source

Bacteriophage therapy created the necessary conditions for successful antibiotic suppression in a periprosthetic hip joint infection: a Case Report. [PDF]

Front Med (Lausanne)
Wahl P, Schläppi M, Loganathan A, Uçkay I, Hodel S, Fritz B, Scheidegger J, Djebara S, Leitner L, McCallin S.   +9 more
europepmc   +1 more source

Contradicting Kuhn's Popular Notion of Scientific Revolution: Conservative Revolutionaries in the History of Biology

Natural Sciences, Volume 6, Issue 3, July 2026.
ABSTRACT Proposing the concept of a conservative revolutionary generally and using the examples of Gregor Mendel, Max Delbrück, and Eric Davidson, I fundamentally call into question Thomas Kuhn's ideas of scientific revolutions. I also highlight some problematic consequences of the increasing appreciation of Kuhn's work among scientists and show that ...
Ute Deichmann
wiley   +1 more source

Bacteriophage therapy: a possible alternative therapy against antibiotic-resistant strains of <i>Klebsiella pneumoniae</i>. [PDF]

Front Microbiol
Abbas S, Kanwar R, Ullah K, Kanwal R, Tajamal M, Aslam MA, Ahmad A, Qadeer A, Huang HY, Chen CC.   +9 more
europepmc   +1 more source

PolyProline Predictor: A web server for empirical sequence‐based prediction of polyproline II helices

Protein Science, Volume 35, Issue 7, July 2026.
Abstract Polyproline II (PPII) helices are extended left‐handed secondary structures increasingly recognized for their roles in molecular recognition, signaling and within intrinsically disordered regions of proteins. Despite their functional importance, predicting regions with propensity to form PPII helices from sequence alone remains challenging due
Rubén López‐Sánchez, David Pantoja‐Uceda, Miguel Mompeán, Douglas V. Laurents   +3 more
wiley   +1 more source

From Norovirus to Andes Hantavirus: Indirect Viral Transmission and Emerging Prevention Strategies for Cruise Ship and Confined Environments

Reviews in Medical Virology, Volume 36, Issue 4, July 2026.
ABSTRACT Cruise ships and other confined travel settings remain highly vulnerable to infectious disease outbreaks. During 2025–2026, multiple norovirus outbreaks and the rare Andes hantavirus outbreak associated with the MV Hondius cruise highlighted the continuing public health challenges posed by both highly transmissible enteric viruses and emerging
Umme Laila Urmi, Mark D. P. Willcox
wiley   +1 more source

Exploration of bacteriophage therapy as a viable alternative to combat antibiotic-resistant bacterial infections: A comprehensive <i>in vitro</i> and <i>in vivo</i> evaluation. [PDF]

Bioinformation
Mehta T, Verma S, Khangura AK, Mahapatra N, Shrivastava K, Gupta S.   +5 more
europepmc   +1 more source