Results 41 to 50 of about 17,041 (213)

Development of a bacteriophage cocktail with high specificity against high-risk avian pathogenic Escherichia coli

Poultry Science
Avian pathogenic Escherichia coli (APEC) is a widespread pathogen that poses a significant threat to the poultry industry globally. A recent typing scheme has proposed several APEC pathotypes, including non-APEC, High Risk non-APEC (HR non-APEC), APEC ...
Rodrigo Norambuena, Victoria Rojas-Martínez, Eduardo Tobar-Calfucoy, Matías Aguilera, Andrea Sabag, María Sofía Zamudio, Pabla Lara, Daniel San Martín, Marcela Zabner, Daniel Tichy, Pamela Camejo, Felipe Rojas, Luis León, Michael Pino, Paola Mora, Soledad Ulloa, Pablo Cifuentes, Hans Pieringer, Nicolás Cifuentes Muñoz   +18 more
doaj   +1 more source

O-Antigen Gene Clusters of Plesiomonas shigelloides Serogroups and Its Application in Development of a Molecular Serotyping Scheme

Frontiers in Microbiology, 2019
Plesiomonas shigelloides is a Gram-negative, flagellated, rod-shaped, ubiquitous, and facultative anaerobic bacterium. It has been isolated from various sources, such as freshwater, surface water, and many wild and domestic animals. P.
Daoyi Xi, Daoyi Xi, Daoyi Xi, Daoyi Xi, Xiaochen Wang, Xiaochen Wang, Xiaochen Wang, Xiaochen Wang, Kexin Ning, Kexin Ning, Kexin Ning, Kexin Ning, Qian Liu, Qian Liu, Qian Liu, Qian Liu, Fuyi Jing, Fuyi Jing, Fuyi Jing, Fuyi Jing, Xi Guo, Xi Guo, Xi Guo, Xi Guo, Boyang Cao, Boyang Cao, Boyang Cao, Boyang Cao   +27 more
doaj   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

New Brucella variant isolated from Croatian cattle

BMC Veterinary Research, 2021
Background A novel Brucella strain closely related to Brucella (B.) melitensis biovar (bv) 3 was found in Croatian cattle during testing within a brucellosis eradication programme.
Silvio Spicic, Maja Zdelar-Tuk, Claire Ponsart, Rene S. Hendriksen, Irena Reil, Guillaume Girault, Pimlapas Leekitcharoenphon, Vesna Rukavina, Martina Rubin, Luca Freddi, Sanja Duvnjak   +10 more
doaj   +1 more source

Salmonella enterica serovar typhi limits the potency of typhoid toxin and ADP‐ribosylating toxin AB to establish a persistent infection

FEBS Open Bio, EarlyView.
The two catalytic subunits of typhoid toxin dissociate from the holotoxin in the ER of an intoxicated cell, but only CdtB exits the ER to generate immunosuppressive effects. PltA is retained in the ER and sequestered from its cytosolic target, thus allowing the anti‐inflammatory effects of CdtB to promote intestinal colonization.
Maria C. Zabala‐Rodriguez, Juliette K. Tinker, Teresa Frisan, Taj Azarian, Ken Teter   +4 more
wiley   +1 more source

Phage Typing of Cholera Vibrio Strains of Serogroup O1, Isolated in the Territory of the Russian Federation in 2024

Проблемы особо опасных инфекций
Currently, cholera remains a relevant infectious disease that requires special vigilance from healthcare professionals and sanitary-epidemiological services.
N. E. Gaevskaya, Yu. V. Sizova, A. V. Tyurina, M. P. Pogozhova, V. D. Kruglikov, O. A. Bogdan   +5 more
doaj   +1 more source

Conformational Switching of Proteins on Material Surfaces Enabled by Peptide‐Oriented Adsorption

Advanced Functional Materials, EarlyView.
Responsive biointerfaces could be achieved using conformationally responsive proteins; however, their interconversion can be lost upon surface adsorption. Herein, we demonstrate that the incorporation a Au binding peptide into calmodulin allows for binding control on Au wherein the protein retains conformational switching. This capability was confirmed
Sakthirupini Ramamurthy, Kyle B. Meerbott, Lorenzo Travaglini, Garima S. Dobhal, Artur Sawicki, Marc R. Knecht, Tiffany R. Walsh, Dominic J. Glover   +7 more
wiley   +1 more source

Beyond Primary Nucleation: Molecular Basis of Peptide Crystal Secondary Nucleation at Soft Interface

Advanced Functional Materials, EarlyView.
High spatiotemporal‐resolution atomic force microscopy directly resolved peptide secondary nucleation (SN) and growth characteristics and mechanisms on HOPG. The landscape of peptide nucleation sites, growth dynamics, molecular‐scale structures, phase transitions, and cross‐seeding processes were realized.
Linhao Sun, Abilesh Kumar, Ayhan Yurtsever   +2 more
wiley   +1 more source

Characterization of Bacteriophage Specific to Bacillus pumilus from Ciapus River in Bogor, West Java, Indonesia

Hayati Journal of Biosciences, 2015
Bacillus pumilus is a spore-forming bacteria that is rod-shaped, gram positive, and aerobic. B. pumilus produced pumilacidins, known to have toxic effects on epithelial cells.
ANIK KUSMIATUN, IMAN RUSMANA, SRI BUDIARTI   +2 more
doaj   +1 more source