Results 91 to 100 of about 187,845 (400)
Comparative genomics of Shiga toxin encoding bacteriophages [PDF]
, 2012 Background Stx bacteriophages are responsible for driving the dissemination of Stx toxin genes (stx) across their bacterial host range. Lysogens carrying Stx phages can cause severe, lifethreatening disease and Stx toxin is an integral virulence factor.
Allison, Heather +6 more
core +2 more sources
The Potential of Phage Therapy in Sepsis
Frontiers in Immunology, 2017 Sepsis remains a difficult clinical challenge, since our understanding of its immunopathology is incomplete and no efficacious treatment currently exists. Its earlier stage results from an uncontrolled inflammatory response to bacteria while in the later
Andrzej Górski +7 more
doaj +1 more source
Framing the Future with Bacteriophages in Agriculture
Viruses, 2018 The ability of agriculture to continually provide food to a growing world population is of crucial importance. Bacterial diseases of plants and animals have continually reduced production since the advent of crop cultivation and animal husbandry ...
A. Svircev, Dwayne R. Roach, A. Castle
semanticscholar +1 more source
Targeted protein degradation in oncology: novel therapeutic opportunity for solid tumours?
Molecular Oncology, EarlyView.Current anticancer therapies are limited by the occurrence of resistance and undruggability of most proteins. Targeted protein degraders are novel, promising agents that trigger the selective degradation of previously undruggable proteins through the recruitment of the ubiquitin–proteasome machinery. Their mechanism of action raises exciting challenges,
Noé Herbel, Sophie Postel‐Vinay
wiley +1 more source
Innovating on Well Biofouling Remediation: A Bacteriophage Cocktail Approach [PDF]
, 2014 Waller Creek Working ...
Bae, Sungwoo +3 more
core +1 more source
Possible role of human ribonuclease dicer in the regulation of R loops
FEBS Open Bio, EarlyView.R loops play an important role in regulating key cellular processes such as replication, transcription, centromere stabilization, or control of telomere length. However, the unscheduled accumulation of R loops can cause many diseases, including cancer, and neurodegenerative or inflammatory disorders. Interestingly, accumulating data indicate a possible
Klaudia Wojcik +2 more
wiley +1 more source
Klebsiella pneumoniae Phage M198 and Its Therapeutic Potential
VirusesThe rapid worldwide spread of antibiotic resistance is quickly becoming an increasingly concerning problem for human healthcare. Non-antibiotic antibacterial agents are in high demand for many Gram-negative bacterial pathogens, including Klebsiella ...
Lika Leshkasheli +6 more
doaj +1 more source
Frontiers in Microbiology, 2016 The objective of this study is to determine the in vitro susceptibility of Georgian bacteriophage cocktails on multi-drug resistant extended-spectrum β-lactamase producing Escherichia coli (ESBL-EC) isolated from patients' blood and urine cultures. 615 E.
Aycan Gundogdu +2 more
doaj +1 more source
Bacteriophages and Biofilms [PDF]
Antibiotics, 2014 Biofilms are an extremely common adaptation, allowing bacteria to colonize hostile environments. They present unique problems for antibiotics and biocides, both due to the nature of the extracellular matrix and to the presence within the biofilm of metabolically inactive persister cells.
Helena M. R. T. Parracho +7 more
openaire +3 more sources
Bacteriophages and Bacterial Plant Diseases
Frontiers in Microbiology, 2017 Losses in crop yields due to disease need to be reduced in order to meet increasing global food demands associated with growth in the human population. There is a well-recognized need to develop new environmentally friendly control strategies to combat ...
S. Abedon +12 more
semanticscholar +1 more source