Results 1 to 10 of about 17,365 (234)
Transdermal Permeation of Drugs in Various Animal Species. [PDF]
Pharmaceutics, 2017 Excised human skin is utilized for in vitro permeation experiments to evaluate the safety and effect of topically-applied drugs by measuring its skin permeation and concentration. However, ethical considerations are the major problem for using human skin to evaluate percutaneous absorption.
Todo H.
europepmc +8 more sources
Pharmaceuticals, 2022 The mechanisms and applications of chitosan and its derivatives in transdermal drug delivery to promote drug permeation were reviewed in this paper.
Jinqian Ma, Yuchen Wang, Rong Lu
doaj +3 more sources
Transdermal permeation of curcumin promoted by choline geranate ionic liquid: Potential for the treatment of skin diseases [PDF]
Saudi Pharmaceutical Journal, 2022 The transdermal permeation of curcumin aided by choline and geranic acid ionic liquid (CAGE-IL) was addressed as a potential treatment for skin diseases.
Rodrigo Boscariol +4 more
doaj +2 more sources
Mechanism investigation of ethosomes transdermal permeation. [PDF]
Int J Pharm X, 2019 Ethosomes are widely used to promote transdermal permeation of both lipophilic and hydrophilic drugs, but the mechanism of interaction between the ethosomes and the skin remains unclear. In this work, it was exploded with several technologies and facilities.
Niu XQ +10 more
europepmc +4 more sources
Performance of Choline Geranate Deep Eutectic Solvent as Transdermal Permeation Enhancer: An In Vitro Skin Histological Study [PDF]
Pharmaceutics, 2021 In the present research work, we addressed the changes in skin by which deep eutectic solvents (DES) enhanced transdermal permeation of bioactive compounds and propose a rationale for this mechanism. Several studies showed that these unusual liquids were
Rodrigo Boscariol +6 more
doaj +2 more sources
Transdermal Permeation and Anti-Inflammation Activities of Novel Sinomenine Derivatives [PDF]
Molecules, 2016 Sinomenine is extracted from Sinomenii caulis (a traditional Chinese medicine), and it is used as the active ingredient in rheumatic arthritis treatments. It has been used in clinical applications for decades.
Zi-Jian Zhao +3 more
doaj +2 more sources
Ionic-liquid-facilitated transdermal absorption of lidocaine hydrochloride. [PDF]
PLoS ONEThe increasing worldwide need for analgesics, along with patients' aversion to injectable anesthetics and limited compliance, highlights the necessity for noninvasive local anesthesia.
Xiaoting Ma +3 more
doaj +2 more sources
Recent developments in skin mimic systems to predict transdermal permeation [PDF]
Current Pharmaceutical Design, 2015 In recent years there has been a drive to create experimental techniques that can facilitate the accurate and precise prediction of transdermal permeation without the use of in vivo studies.
Waters, Laura J.
core +4 more sources
Asian Journal of Pharmaceutical Sciences, 2023 Overlook of chiral consideration in transdermal drug delivery increases administrated dose and risk of side effects, decreasing therapeutical effects. To improve the transdermal delivery efficiency of eutomer, this work focused on investigating the law ...
Yang Zhang +9 more
doaj +1 more source
Pharmaceutics, 2021 Bisoprolol hemifumarate (BH) is an antihypertensive drug that is used as first-line treatment for chronic hypertension and angina pectoris. Our study was performed to enhance the transdermal delivery of BH, a hydrophilic drug active with high molecular ...
Mahmoud H. Teaima +5 more
doaj +1 more source