Transdermal permeation of curcumin promoted by choline geranate ionic liquid: Potential for the treatment of skin diseases [PDF]
Saudi Pharmaceutical Journal, 2022 The transdermal permeation of curcumin aided by choline and geranic acid ionic liquid (CAGE-IL) was addressed as a potential treatment for skin diseases.
JOSÉ Martins de Oliveira Junior +2 more
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Performance of Choline Geranate Deep Eutectic Solvent as Transdermal Permeation Enhancer: An In Vitro Skin Histological Study [PDF]
Pharmaceutics, 2021 In the present research work, we addressed the changes in skin by which deep eutectic solvents (DES) enhanced transdermal permeation of bioactive compounds and propose a rationale for this mechanism. Several studies showed that these unusual liquids were
Thaïs J Oliveira +2 more
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Transdermal Permeation of Drugs in Various Animal Species [PDF]
Pharmaceutics, 2017 Excised human skin is utilized for in vitro permeation experiments to evaluate the safety and effect of topically-applied drugs by measuring its skin permeation and concentration. However, ethical considerations are the major problem for using human skin to evaluate percutaneous absorption.
Hiroaki Tōdō, Tōdō Hiroaki
exaly +7 more sources
Pharmaceuticals, 2022 The mechanisms and applications of chitosan and its derivatives in transdermal drug delivery to promote drug permeation were reviewed in this paper.
Jinqian Ma, Yuchen Wang, Rong Lu
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Mechanism investigation of ethosomes transdermal permeation. [PDF]
Int J Pharm X, 2019 Ethosomes are widely used to promote transdermal permeation of both lipophilic and hydrophilic drugs, but the mechanism of interaction between the ethosomes and the skin remains unclear. In this work, it was exploded with several technologies and facilities.
Niu XQ +10 more
europepmc +4 more sources
Enhancement of transdermal permeation of cannabinoids and their pharmacodynamic evaluation in rats. [PDF]
Int J Pharm, 2022 The objective of the present study was to enhance the transdermal permeation of cannabinoids: cannabidiol (CBD), cannabigerol (CBG) and tetrahydrocannabivarin (THCV) using chemical permeation enhancer approach and evaluate them for their anti-inflammatory effect in vivo in a paw edema model in rats.
Salau O, Bagde A, Kalvala A, Singh M.
europepmc +3 more sources
Novel chemical permeation enhancers for transdermal drug delivery
Asian Journal of Pharmaceutical Sciences, 2014 Transdermal drug delivery has been accepted as a potential non-invasive route of drug administration, with advantages of prolonged therapeutic action, decreased side effect, easy use and better patient compliance.
Peng Quan, Xiaochang Liu
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Transdermal Permeation and Anti-Inflammation Activities of Novel Sinomenine Derivatives
Molecules, 2016 Sinomenine is extracted from Sinomenii caulis (a traditional Chinese medicine), and it is used as the active ingredient in rheumatic arthritis treatments. It has been used in clinical applications for decades.
Chang Zhao +2 more
exaly +3 more sources
The self-assembly mechanisms of glycyrrhizic acid: Permeation enhancement and transdermal applications [PDF]
International Journal of Pharmaceutics: XGlycyrrhizic acid (GA) is an amphiphilic triterpenoid saponin compound derived from licorice. This review first summarizes the behaviors and evolution mechanisms of GA forming different nanostructures (dimers, micelles, nanoparticles, nanofibers, and ...
Lin Zhou +3 more
doaj +2 more sources
Ionic-liquid-facilitated transdermal absorption of lidocaine hydrochloride. [PDF]
PLoS ONEThe increasing worldwide need for analgesics, along with patients' aversion to injectable anesthetics and limited compliance, highlights the necessity for noninvasive local anesthesia.
Xiaoting Ma +3 more
doaj +2 more sources