Results 31 to 40 of about 7,205 (188)

Preparation, Characterization and Ex vivo Permeability Study of Transdermal Apixaban O/W Nanoemulsion Based Gel

Iraqi Journal of Pharmaceutical Sciences, 2020
This study designed to prepare ultrafine apixaban (APX) o/w nanoemulsion (NE) based gel with droplet size below 50 nm as a good method for transdermal APX delivery without using permeation enhancer, alternatively, the formulation components itself act as
Mustafa R. Abdulbaqi, Nawal A.Rajab
doaj   +1 more source

In vitro evaluation of transdermal nicotine delivery systems commercially available in Brazil

Brazilian Journal of Pharmaceutical Sciences, 2013
The aim of this study was to develop and validate a method for evaluating the release and skin permeation from transdermal nicotine patches using the vertical diffusion cell (VDC).
André Luís Morais Ruela, Eduardo Costa Figueiredo, Aline Gravinez Perissinato, Ana Carolina Zogbi Lima, Magali Benjamim Araújo, Gislaine Ribeiro Pereira   +5 more
doaj   +1 more source

Biointegrated Battery‐Based Electroceuticals

Advanced Materials, EarlyView.
Biointegrated batteries go beyond passive power to serve as active therapeutic platforms for delivering programmable electrical cues and bioactive agents. This review examines their mechanisms and applications and provides a framework to guide battery‐based therapeutic design and clinical translation.
Yan Zhou, Zhilian Yue, Zhiqi Chen, Danming Chao, Xiaoteng Jia, Gordon Wallace, Caiyun Wang   +6 more
wiley   +1 more source

Status of surfactants as penetration enhancers in transdermal drug delivery

Journal of Pharmacy and Bioallied Sciences, 2012
Surfactants are found in many existing therapeutic, cosmetic, and agro-chemical preparations. In recent years, surfactants have been employed to enhance the permeation rates of several drugs via transdermal route.
Iti Som, Kashish Bhatia, Mohd. Yasir
doaj   +1 more source

Patterned Screen‐Printing Process for Substrate‐Free and Scalable Hyaluronic Acid Microneedle Arrays

Advanced Materials Technologies, EarlyView.
A substrate‐free microneedle array comprising a hybrid hyaluronic acid ink was fabricated via a scalable screen‐printing process for flexible transdermal drug delivery. Defect‐free mold filling was achieved using a vacuum‐assisted jig and a delayed drying system, and the use of this versatile platform for multi‐drug patterning and ex vivo skin ...
Sanghyun Ahn, Jaeho Kim, SeungHyun Park, WonHyoung Ryu   +3 more
wiley   +1 more source

Effect of Piperine on Skin Permeation of Curcumin from a Bacterially Derived Cellulose-Composite Double-Layer Membrane for Transdermal Curcumin Delivery

Scientia Pharmaceutica, 2018
Curcumin is a naturally occurring substance with various pharmacological activities. It has not been developed as a drug because of its low bioavailability due to its low solubility and absorption. Piperine is a natural enhancer that is popularly used to
Chutima Jantarat, Pornpak Sirathanarun, Somruedee Boonmee, Wanida Meechoosin, Husna Wangpittaya   +4 more
doaj   +1 more source

Design, synthesis of novel lipids as chemical permeation enhancers and development of nanoparticle system for transdermal drug delivery. [PDF]

PLoS ONE, 2013
In the present study, we designed and developed novel lipids that include (Z)-1-(Octadec-9-en-1-yl)-pyrrolidine (Cy5T), 1, 1-Di-((Z)-octadec-9-en-1-yl)pyrrolidin-1-ium iodide (Cy5), (Z)-1-(Octadec-9-en-1-yl)-piperidine (Cy6T), and 1, 1-Di-((Z)-octadec-9 ...
Srujan Marepally, Cedar H A Boakye, Punit P Shah, Jagan Reddy Etukala, Adithi Vemuri, Mandip Singh   +5 more
doaj   +1 more source

Nanostructured lipid carriers mediated transdermal delivery of trandolapril as an impeccable therapeutic approach against hypertension: Development, characterization and in vivo evaluation

OpenNano, 2023
The study aimed to design trandolapril-embedded nanostructured lipid carriers (NLCs) transdermal patch and evaluate its in vitro drug permeation, bioavailability and pharmacokinetics.
Ramankit Jaiswal, Rita Wadetwar
doaj   +1 more source

Effect of different enhancers on the transdermal permeation of insulin analog [PDF]

International Journal of Pharmaceutics, 2010
Using chemical penetration enhancers (CPEs), transdermal drug delivery (TDD) offers an alternative route for insulin administration, wherein the CPEs reversibly reduce the barrier resistance of the skin. However, there is a lack of sufficient information concerning the effect of CPE chemical structure on insulin permeation.
K M, Yerramsetty, V K, Rachakonda, B J, Neely, S V, Madihally, K A M, Gasem   +4 more
openaire   +2 more sources

Making Sweat Measurable: Induction, Sampling, and Refreshment in Wearable Biofluid Sensing

Advanced Science, EarlyView.
Wearable sweat sensing relies not only on chemical detection but also on controlled biofluid management. This Review integrates sweat physiology, induction strategies, and microfluidic sampling architectures, demonstrating how flux, transport, and refreshment shape measurement reliability.
Soyoung Shin, Wei Gao
wiley   +1 more source