Results 31 to 40 of about 88,006 (229)

The Development of Transdermal Piroxicam Using HPMC Matrices With PVP K-30 as a Penetration Enhancer [PDF]

, 2006
The physicochemical properties such as solubility, partition coefficient, and membrane permeability of a drug are required for formulating and estimating drugs absorption that pass through biological membranes.
Aryani, Ni Luh Dewi
core   +2 more sources

Temperature influencing permeation pattern of alfuzosin: An investigation using DoE

Medicina, 2015
Background and objective: There has been relatively little investigation of the effect of temperature on skin permeation compared to other methods of penetration enhancement.
Satyanarayan Pattnaik, Kalpana Swain, Jupally Venkateshwar Rao, Talla Varun, Subrata Mallick   +4 more
doaj   +1 more source

Strategies To Enhance Transdermal Drug delivery [PDF]

المجلة العراقية للصيدلة, 2021
Background: Transdermal drug delivery system (TDDS) is a promising delivery system that provides controlled drug release at a predetermined time. It has many advantages such as bypassing first-pass effect, increase patient convenience by providing single
Mais Saadallah, Omar Hamid
doaj   +1 more source

Transdermal Drug Delivery of Tazarotene: Determining Tazarotene’s Potential in Local Transdermal Therapy

Pharmaceutics, 2023
Retinoid-based drugs, while effective, are associated with systemic toxicity. Topical alternatives offer a safer option, and tazarotene, a third-generation synthetic retinoid, holds promise.
Helena Hamzehpour, Ástrós Óskarsdóttir, Helgi Jónsson, Fjóla Jónsdóttir, Ólafur E. Sigurjónsson, Bergthora S. Snorradottir   +5 more
doaj   +1 more source

Effect of continuous phase drug concentration, evaporation and partitioning on transdermal drug permeation kinetics with lipophilic vehicles [PDF]

, 2008
In this work the dependence of transdermal drug permeation kinetics on continuous phase drug concentration, partitioning between formulation phases, partitioning between stratum corneum and continuous oil phase and evaporation of volatile formulation ...
Reiser, Miriam Regina Luise
core   +1 more source

Non-invasive Transdermal Delivery of Human Insulin Using Ionic Liquids: In vitro Studies

Frontiers in Pharmacology, 2020
In this research project, synthesis and characterization of ionic liquids and their subsequent utilization as facilitators of transdermal delivery of human insulin was pursued.
Ludmilla R. Jorge, Liliam K. Harada, Erica C. Silva, Welida F. Campos, Fernanda C. Moreli, Gustavo Shimamoto, Jorge F. B. Pereira, José M. Oliveira, Matthieu Tubino, Marta M. D. C. Vila, Victor M. Balcão, Victor M. Balcão   +11 more
doaj   +1 more source

Electret Enhances Transdermal Drug Permeation

Biological and Pharmaceutical Bulletin, 2008
Electrets are polymeric discs that carry semi permanent electrostatic charge. These provide electrostatic potentials in the range of 500 to 3,000 V. In the current work, the effect of electret exposure on the skin permeability was investigated. Transdermal transport studies were carried out across porcine epidermis in Franz diffusion cells.
Narasimha Sathyanarayana Murthy, Narasimha Sathyanarayana, Boguda, Vishwanath Anantharamaiah, Payasada, Kotrappa   +2 more
openaire   +2 more sources

Effect of microneedles on transdermal permeation enhancement of amlodipine [PDF]

Drug Delivery and Translational Research, 2017
The present study aimed to investigate the effect of microneedle (MN) geometry parameters like length, density, shape and type on transdermal permeation enhancement of amlodipine (AMLO). Two types of MN devices viz. AdminPatch® arrays (ADM) (0.6, 1.2 and 1.5 mm lengths) and laboratory-fabricated polymeric MNs (PM) of 0.6 mm length were employed. In the
Buchi N, Nalluri, Chandrateja, Uppuluri, Jyothirmayee, Devineni, Atul, Nayak, Karthik J, Nair, Benjamin R, Whiteside, Diganta B, Das   +6 more
openaire   +2 more sources

Investigation of transdermal permeation of atorvastatinloaded microemulsions

Tropical Journal of Pharmaceutical Research, 2022
Purpose: To develop microemulsions containing atorvastatin for transdermal application, which will improve the bioavailability and reduce the side effects associated with the oral administration of atorvastatin.Methods: Atorvastatin-loaded microemulsions (MEs) were developed using tween 80 as a nonionic surfactant, isopropyl myristate, polyethylene ...
Alkrad, Jamal Alyoussef, Musa, Raad J., Al-Hijjawi, Rawan, Hussein- Al-Ali, Samer H.   +3 more
openaire   +2 more sources

Surfactant and temperature effects on paraben transport through silicone membranes [PDF]

, 2013
This study investigates the effects of two surfactants (one anionic and one non-ionic) and controlled modifications in temperature (298–323 K) on the permeation of two structurally similar compounds through a silicone membrane using a Franz diffusion ...
Bibi, Aisha, Mitchell, John C., Dennis, Laura, Waters, Laura J.   +3 more
core   +1 more source